Patents by Inventor Ana Maria Torres
Ana Maria Torres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9757349Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: GrantFiled: August 10, 2016Date of Patent: September 12, 2017Assignee: FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL GREGORIO MARANONInventors: Alberto Tejedor Jorge, Alberto Lazaro Fernandez, Sonia Camano Paez, Ana Maria Torres Redondo, Jose Antonio Lazaro Manero, Manuela Castilla Barba, Maria del Carmen De Lucas Collantes
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Publication number: 20170035718Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: ApplicationFiled: August 10, 2016Publication date: February 9, 2017Inventors: Alberto TEJEDOR JORGE, Alberto LAZARO FERNANDEZ, Sonia CAMANO PAEZ, Ana Maria TORRES REDONDO, Jose Antonio LAZARO MANERO, Manuela CASTILLA BARBA, Maria del Carmen DE LUCAS COLLANTES
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Patent number: 9522128Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: GrantFiled: November 13, 2015Date of Patent: December 20, 2016Assignee: Fundacion Para La Investigacion Biomedica Del Hospital Gregorio MaranonInventors: Alberto Tejedor Jorge, Alberto Lazaro Fernandez, Sonia Camano Paez, Ana Maria Torres Redondo, Jose Antonio Lazaro Manero, Manuela Castilla Barba, Maria del Carmen De Lucas Collantes
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Publication number: 20160136121Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Inventors: Alberto TEJEDOR JORGE, Alberto LAZARO FERNANDEZ, Sonia CAMANO PAEZ, Ana Maria TORRES REDONDO, Jose Antonio LAZARO MANERO, Manuela CASTILLA BARBA, Maria del Carmen DE LUCAS COLLANTES
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Patent number: 9216185Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: GrantFiled: July 11, 2008Date of Patent: December 22, 2015Assignee: Fundacion Para La Investigacion Biomedica Del Hospital Gregorio MaranonInventors: Alberto Tejedor Jorge, Alberto Lazaro Fernandez, Sonia Camaño Paez, Ana Maria Torres Redondo, José Antonio Lazaro Manero, Manuela Castilla Barba, María del Carmen De Lucas Collantes
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Publication number: 20110165264Abstract: Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects.Type: ApplicationFiled: July 11, 2008Publication date: July 7, 2011Inventors: Alberto Tejedor Jorge, Alberto Lazaro Fernandez, Sonia Camaño Paez, Ana Maria Torres Redondo, José Antonio Lazaro Manero, Manuela Castilla Barba, Maria del Carmen De Lucas Collantes
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Publication number: 20100155551Abstract: It is a principal object of the invention to provide a hanging device with sufficient support, functionality and simplicity to fulfill many designer closet and/or commercial functions. The hanging device of the invention is compact and has a reinforced structure, thereby taking into account both esthetic and practical aspects. Additionally the hanging device also provides designer uses. The hanging device invention comprises two connective fixtures, two vertical support members, and a hanging rod. The two connective fixtures are welded to the vertical support rod, which is mitered and welded to the hanging rod. The welding hanging device forms a solid device which is then suspended from a ceiling or other suitable overhead plane.Type: ApplicationFiled: December 24, 2008Publication date: June 24, 2010Inventor: Ana Maria Torres
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Publication number: 20100155351Abstract: It is a principal object of the invention to provide a hanging device with sufficient support, functionality and simplicity to fulfill many designer residential and/or commercial functions. The hanging device of the invention is compact and has a reinforced structure, thereby taking into account both esthetic and practical aspects. Additionally the hanging device also provides designer uses. According to one aspect of the invention, the hanging device comprises two vertical support members, a hanging rod, a horizontal support rod, and footings. The two footings contain rubber pads on the under side that has contact with the flooring. The footings are welded to the vertical support rod, which is mitered and welded to the hanging rod and horizontal support rod. According to another aspect of the invention, the above hanging device can include a secondary horizontal support rod for additional support and hanging space.Type: ApplicationFiled: December 24, 2008Publication date: June 24, 2010Inventor: Ana Maria Torres
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Patent number: 6431181Abstract: A hair coloring cap, for use in selectively changing the color of multiple strands of hair on a head of a user, includes a support frame for supporting a plurality of strut members in a spaced apart positions around the head of the user. Each of a plurality of wing members are attached to one of the plurality of strut members and extends therefrom to a length approximately that of the multiple strands of hair to be colored. The cap is positioned on the head and multiple strands of hair are pulled between the strut members so that the hair is positioned on an upper surface of each of the plurality of wing members. A coloring agent is applied to the upper surface of each of the plurality of wing members, such that the coloring agent functionally coats each of the multiple strands of hair to be colored. Each of the plurality of wing members is then folded, thereby trapping the hair and the coloring agent.Type: GrantFiled: April 4, 2000Date of Patent: August 13, 2002Inventor: Ana Maria Torres