Patents by Inventor Ana Maria Vázguez López

Ana Maria Vázguez López has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-idiotypic monoclonal antibodies, their use in the active immunotherapy of malignant tumors, and compositions including the anti-idiotypic monoclonal antibodies
    Patent number: 6491914
    Abstract: An anti-idiotypic monoclonal antibody that is specific against the N-glycolyl residues of gangliosides, particularly those expressed by cancer cells. The monoclonal antibody is useful as an immunomodulator for cancer treatment. Specifically, the anti-Id monoclonal antibody of the present invention is capable of inducing a predominant anti-idiotypic response in xenogeneic models. The anti-idiotypic monoclonal antibody also exerts a protective effect against malignant tumors in animals.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: December 10, 2002
    Assignee: Centro de Inmunologia Molecular
    Inventors: Ana Maria Vázguez López, Rolando Pérez Rodriguez, Eladio Iglesis Guerra, Alexis Pérez, Gumersinda Bombino Lopez, Irene Beausoleil Delgado
  • Anti-idiotypic monoclonal antibodies and compositions including the anti-idiotypic monoclonal antibodies
    Patent number: 6063379
    Abstract: An anti-idiotypic monoclonal antibody that is specific against the N-glycolyl residues of gangliosides, particularly those expressed by cancer cells. The monoclonal antibody is useful as an immunomodulator for cancer treatment. Specifically, the anti-idiotype monoclonal antibody of the present invention is capable of inducing a predominant anti-idiotypic response in xenogeneic models. The anti-idiotypic monoclonal antibody also exerts a protective effect against malignant tumors in animals.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: May 16, 2000
    Assignee: Centro de Inmunologia Molecular
    Inventors: Ana Maria Vazguez Lopez, Rolando Perez Rodriguez, Eladio Iglesis Guerra, Alexis Perez, Gumersinda Bombino Lopez, Irene Beausoleil Delgado
  • Anti ganglioside monoclonal antibodies
    Patent number: 5817513
    Abstract: The present invention relates to immunotherapy strategies for the treatment of malignancies. The present immunotherapy strategies have gangliosides as a target. Gangliosides are glycosphingolipids which are present on normal cells and on malignant cells. On malignant cells they are more abundant and expressed in a different organization and conformation. The present invention provides antibodies which recognize these gangliosides, which antibodies are specific, have recurrent idiotypes and have value as immunoregulators. The invention further provides anti-idiotypic antibodies against anti-ganglioside antibodies. These are useful in vaccination strategies.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: October 6, 1998
    Assignee: Centro de Inmunologia Molecular
    Inventors: Ana Maria Vazguez Lopez, Angel Mauro Alfonso Fernandez, Rolando Perez Rodriguez, Amparo E. Macias Abraham, Carlos Manuel Alvarez Valcarcel, Maria Eliana Lanio Ruiz