Patents by Inventor Ana Montero Aguado

Ana Montero Aguado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biphenyl derived thiamides as calpain inhibitors
    Patent number: 7476754
    Abstract: The present invention relates to compounds derived from biphenyl with activity as calpain inhibitors. One compound of the present invention is a 2,2?-disubstituted biphenyl, where the substituents in the 2 and 2? positions of the biphenyl skeleton are chains containing structures related to amino acids, including fragments of aminocarbonylic compounds where at least one of the substituents in said 2- or 2?-positions is bonded to the biphenyl skeleton via a thiocarbonyl group, forming compounds with thioamide functionality. The present invention also encompasses any of the conformational isomers (atropisomers) of said compound of formula I. The compounds of formula I have application in the preventive or therapeutic treatment of a degenerative disease.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: January 13, 2009
    Assignee: Consejo Superior de Investigaciones Cientificas
    Inventors: Bernardo Herradon Garcia, Mercedes Alonso Giner, Esperanza Benito Cano, Antonio Chana Lopez, Ana Montero Aguado
  • Biphenyl Derived Thiamides as Calpain Inhibitors
    Publication number: 20070270480
    Abstract: The present invention relates to compounds derived from biphenyl with activity as calpain inhibitors. One compound of the present invention is a 2,2?-disubstituted biphenyl, where the substituents in the 2 and 2? positions of the biphenyl skeleton are chains containing structures related to amino acids, including fragments of aminocarbonylic compounds where at least one of the substituents in said 2- or 2?-positions is bonded to the biphenyl skeleton via a thiocarbonyl group, forming compounds with thioamide functionality. The present invention also encompasses any of the conformational isomers (atropisomers) of said compound of formula I. The compounds of formula I have application in the preventive or therapeutic treatment of a degenerative disease.
    Type: Application
    Filed: May 6, 2005
    Publication date: November 22, 2007
    Inventors: Bernardo Herradon Garcia, Mercedes Alonso Giner, Esperanza Benito Cano, Antonio Chana Lopez, Ana Montero Aguado