Patents by Inventor Ana P. Gomes

Ana P. Gomes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF AGE-RELATED AND MITOCHONDRIAL DISEASES BY INHIBITION OF HIF-1 ALPHA FUNCTION
    Publication number: 20200291100
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction.
    Type: Application
    Filed: October 25, 2019
    Publication date: September 17, 2020
    Applicants: President and Fellows of Harvard College, Massachusetts Institute of Technology
    Inventors: David A. Sinclair, Ana P. Gomes, Eric Bell
  • NAD BIOSYNTHESIS AND PRECURSORS FOR THE TREATMENT AND PREVENTION OF CANCER AND PROLIFERATION
    Publication number: 20180338991
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of cancer by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.
    Type: Application
    Filed: December 7, 2017
    Publication date: November 29, 2018
    Applicants: President and Fellows of Harvard College, NewSouth Innovations Pty Limited
    Inventors: David A. Sinclair, Ana P. Gomes, Lindsay Wu
  • TREATMENT OF AGE-RELATED AND MITOCHONDRIAL DISEASES BY INHIBITION OF HIF-1 ALPHA FUNCTION
    Publication number: 20180118819
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction.
    Type: Application
    Filed: May 26, 2017
    Publication date: May 3, 2018
    Applicants: President and Fellows of Harvard College, Massachusetts Institute of Technology
    Inventors: David A. Sinclair, Ana P. Gomes, Eric Bell
  • NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation
    Patent number: 9877981
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of cancer by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: January 30, 2018
    Assignees: President and Fellows of Harvard College, NewSouth Innovations Pty Limited
    Inventors: David A. Sinclair, Ana P. Gomes, Lindsay Wu
  • NAD BIOSYNTHESIS AND PRECURSORS FOR THE TREATMENT AND PREVENTION OF CANCER AND PROLIFERATION
    Publication number: 20150313930
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of cancer by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.
    Type: Application
    Filed: October 9, 2013
    Publication date: November 5, 2015
    Inventors: David A. Sinclair, Ana P. Gomes
  • TREATMENT OF AGE-RELATED AND MITOCHONDRIAL DISEASES BY INHIBITION OF HIF-1 ALPHA FUNCTION
    Publication number: 20150266946
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction.
    Type: Application
    Filed: October 9, 2013
    Publication date: September 24, 2015
    Inventors: David A. Sinclair, Ana P. Gomes, Eric Bell
  • NAD BIOSYNTHESIS AND PRECURSORS IN THE PREVENTION AND TREATMENT OF INFLAMMATION
    Publication number: 20150265642
    Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of disorders associated with inflammation by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.
    Type: Application
    Filed: October 9, 2013
    Publication date: September 24, 2015
    Inventors: David A. Sinclair, Ana P. Gomes