Patents by Inventor Ana Paula Duarte de Souza

Ana Paula Duarte de Souza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound, use, anti-tumor pharmaceutical composition, gene construct for polypeptide expression, process for the production, process for the evaluation of tumor cells, method of sensitization of tumor cells to chemotherapeutic
    Patent number: 10508139
    Abstract: The use of HspBP1 protein or part thereof for the preparation of an anti-tumor pharmaceutical composition, and its optional combination with one or more chemotherapeutic agents. A gene construct for the expression of said protein; a production process; a process of evaluation of tumor cells; and a method of sensitization of tumors to chemotherapeutic agents. A new experimental model in vivo and in vitro for the development/evaluation of anti-tumor agents. The pharmaceutical compositions provide anti-tumor action and have high specificity to neoplastic cells, resulting in less cytotoxicity to normal dividing cells, in part as a solution to the drawbacks of currently known chemotherapy therapeutic regimens.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: December 17, 2019
    Assignee: União Brasileira de Educação e Assistência, mantenedora da PUCRS
    Inventors: Cristina Beatriz Cazabuena Bonorino, Ana Paula Duarte de Souza
  • COMPOUND, USE, ANTI-TUMOR PHARMACEUTICAL COMPOSITION,GENE CONSTRCT FOR POLYPEPTIDE EXPRESSION, PROCESS FOR THE PRODUCTION, PROCESS FOR THE EVALUATION OF TUMOR CELLS, METHOD OF SENSITIZATION OF TUMOR CELLS TO CHEMOTHERAPEUTIC
    Publication number: 20160368955
    Abstract: The use of HspBP1 protein or part thereof for the preparation of an anti-tumor pharmaceutical composition, and its optional combination with one or more chemotherapeutic agents. A gene construct for the expression of said protein; a production process; a process of evaluation of tumor cells; and a method of sensitization of tumors to chemotherapeutic agents. A new experimental model in vivo and in vitro for the development/evaluation of anti-tumor agents. The pharmaceutical compositions provide anti-tumor action and have high specificity to neoplastic cells, resulting in less cytotoxicity to normal dividing cells, in part as a solution to the drawbacks of currently known chemotherapy therapeutic regimens.
    Type: Application
    Filed: December 27, 2013
    Publication date: December 22, 2016
    Applicant: União Brasileira de Educação e Assistência, mantenedora da PUCRS
    Inventors: Cristina Beatriz Cazabuena Bonorino, Ana Paula Duarte de Souza