Patents by Inventor Ana Rodriguez
Ana Rodriguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959065Abstract: Provided are bioactive compositions and metabolites derived from Bacillus and particularly Bacillus megaterium cultures responsible for controlling pests as well as their methods of use for controlling pests. Further provided are pesticidal Bacillus megaterium strains.Type: GrantFiled: June 9, 2022Date of Patent: April 16, 2024Assignee: PRO FARM GROUP, INC.Inventors: Ratnakar Asolkar, Ana Lucia Cordova-Kreylos, Margarita Rodriguez, Carly Todd, Debora Wilk, Pamela G. Marrone
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Publication number: 20230405136Abstract: Combinations of boron compounds and adjuvants and compositions thereof are suitable for use in a method to induce myotube formation and suppress cell mortality in a mammal in need thereof and for the treatment of epithelial cancers. Compositions comprise boron compounds, adjuvants and support platforms, which enhance the effect of synergistic activation of the boron cell membrane transporter (NaBC1) and adhesion receptors in cells. The combinations and compositions are for the treatment of pathophysiological condition, which affects skeletal muscle, such as dystrophy and epithelial cancer. The combinations and compositions can be included in the field of medical chemistry or pharmacology.Type: ApplicationFiled: October 4, 2021Publication date: December 21, 2023Applicant: Consorcio Centro De Investigacion Biomedica En Red, M.P.Inventors: Patricia Rico Tortosa, Rafael Castillo Romero, Ana Rodriguez Romano
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Publication number: 20210290254Abstract: Disclosed are tools and devices for use in repairing an intervertebral disc. The devices include an anchor configured to be secured in a vertebra adjacent the intervertebral disc and a prosthesis having an active part that is configured for placement inside the nucleus of the disc. The tools include an anchor placement tool that includes a chisel for carving the vertebra and a rotatable part that is used for engaging with and screwing the anchor into the vertebra. The tools also include a prosthesis placement tool that is configured to support and facilitate an attachment of the prosthesis to the anchor and to deploy the active part of the prosthesis in the nucleus of the disc. According to one embodiment the prosthesis placement tool is equipped with electronics for the purpose of verifying a corrected attachment of the prosthesis to the anchor. According to other embodiments, the electronics are included in a separate checker tool.Type: ApplicationFiled: April 1, 2021Publication date: September 23, 2021Inventors: Marc SERRAHIMA TORNEL, Salvador LLAS VARGAS, Ana RODRÍGUEZ ALONSO, Lluís CHICO ROCA
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Patent number: 10189123Abstract: A system for out of autoclave bonded repairs which including a fixing structure (1) to the composite area to be repaired, including a frame (4) and fixing parts (5, 19) attached to the frame (4), a movable structure (2) able to be attached either to the fixing structure (1) or to the patch manufacturing table (3), which includes three shafts (6, 6?, 6?) and three engines (7, 7?, 7?) configured to be able to move the tooling support in the three axes X, Y and Z, and a tooling support of either scanning tool (9), milling tool (10), patch cutting tool (11) or composite patch handle tool (11), and a patch manufacturing structure (3).Type: GrantFiled: October 5, 2016Date of Patent: January 29, 2019Assignee: Airbus Operations SLInventors: Ana Rodriguez Bellido, Jose Sanchez Gomez, Rafael Avila Dominguez, Enric Vila Papell, Rebeca Anguiano Zarranz, Juan Ignacio Forcen Carvalho
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Patent number: 9868943Abstract: Virion-associated peptidoglycan hydrolases have a potential as antimicrobial agents due to their ability to lyse Gram positive bacteria on contact. Fusion proteins HydH5SH3b and HydH5Lyso comprising full-length peptidoglycan hydrolase HydH5 from the Staphylococcus aureus bacteriophage vB_SauS-phi-IPLA88 in combination with the SH3b cell wall-binding domain from lysostaphin or full length lysostaphin, respectively, exhibited high lytic activity against live S. aureus cells. CHAPSH3b, a HydH5 CHAP (cysteine, histidine-dependent amidohydrolase/peptidase) domain from truncated HydH5 in combination with the SH3b domain of lysostaphin, exhibited the highest lytic activity against live S. aureus cells. HydH5 and its derivative fusions lysed bovine and human S. aureus, methicillin-resistant S. aureus (MRSA) N315 strain, and human S. epidermidis strains in zymogram, plate lysis and turbidity reduction assays.Type: GrantFiled: February 12, 2015Date of Patent: January 16, 2018Assignee: The United States of America, as represented by The Secretary of AgricultureInventors: David M. Donovan, Lorena Rodriguez Rubio, Beatriz Martinez Fernandez, Ana Rodriguez, Pilar Garcia Suarez
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Patent number: 9782266Abstract: A device (1, 100) for repairing an intervertebral disc comprising an anchoring body (2, 102), suitable for being advanced into and secured in one of the vertebrae adjacent the intervertebral disc; and a prosthesis (3, 103, 203, 303) attachable in a secure coupling position to the anchoring body (2, 102) and adapted for retaining or replacing the nucleus pulposus in an interior space of an outer annulus of the intervertebral disc, the anchoring body supporting and arranging in the cited coupling position the prosthesis such that the prosthesis is oriented to in a direction toward and through a hole in the outer annulus, the prosthesis comprising at least one active portion (4) adapted to assume and maintain a first placement shape (A) suitable for permitting the active portion to be inserted into and through the hole in the outer annulus during a placement thereof into the interior space of the outer annulus, and at least a second operative shape (B) suitable for at least partially occluding the hole in the ouType: GrantFiled: March 12, 2014Date of Patent: October 10, 2017Assignee: NEOS SURGERY, S.L.Inventors: Marc Serrahima Tornel, Salvador Llas Vargas, Ana Rodriguez Alonso, Montserrat Charles-Harris Ferrer, Lluis Chico Roca, Pablo Clavel Laria
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Publication number: 20170095894Abstract: A system for out of autoclave bonded repairs which including a fixing structure (1) to the composite area to be repaired, including a frame (4) and fixing parts (5, 19) attached to the frame (4), a movable structure (2) able to be attached either to the fixing structure (1) or to the patch manufacturing table (3), which includes three shafts (6, 6?, 6?) and three engines (7, 7?, 7?) configured to be able to move the tooling support in the three axes X, Y and Z, and a tooling support of either scanning tool (9), milling tool (10), patch cutting tool (11) or composite patch handle tool (11), and a patch manufacturing structure (3).Type: ApplicationFiled: October 5, 2016Publication date: April 6, 2017Inventors: Ana RODRIGUEZ BELLIDO, Jose SANCHEZ GOMEZ, Rafael AVILA DOMINGUEZ, Enric VILA PAPELL, Rebeca ANGUIANO ZARRANZ, Juan Ignacio FORCEN CARVALHO
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Patent number: 9572349Abstract: The invention provides a method for controlling Huanglongbing (HLB) disease of citrus plants through expressing genes encoding synthases for sesquiterpenes such as ?-caryophyllene, and ?-copaene, and combinations thereof, in citrus plants. Methods of controlling HLB comprising applying at least one purified sesquiterpene, which repels Diaphorina citri and/or Tryoza erytrae psyllid insects, so as to control the HLB disease of citrus plants, are also disclosed.Type: GrantFiled: June 8, 2015Date of Patent: February 21, 2017Assignees: Fundo de Defesa da Citricultura—Fundecitrus, Instituto Valenciano de Investigaciones AgrariasInventors: Berta Alquezar García, Ana Rodriguez Baixauli, Josep Peris Rodrigo, Leandro Peña García, Andréia Henrique, Marcelo Pedreira De Miranda, Pedro Takao Yamamoto, Marcel Bellato Spósito, Nelson Arno Wulff, Diva do Carmo Teixeira, Antonio Juliano Ayres, Newton Cavalcanti De Noronha, Jr., José Maurício Simões Bento, José Roberto Postali Parra
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Publication number: 20160152566Abstract: The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine. The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.Type: ApplicationFiled: July 8, 2014Publication date: June 2, 2016Inventors: Antonio FERNÁNDEZ MEDARDE, Librada Maria CANEDO HERNÁNDEZ, María De Los Ángeles VINUESA-NAVARRO, José María SÁNCHEZ LÓPEZ, Belinda CALVO PELAZ, Marta MARTÍNEZ INSUA, Ana RODRÍGUEZ-QUESADA, Melissa CARCÍA-CABALLERO, Miguel-Ángel MEDINA-TORRES
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Publication number: 20160015521Abstract: A device (1, 100) for repairing an intervertebral disc comprising an anchoring body (2, 102), suitable for being advanced into and secured in one of the vertebrae adjacent the intervertebral disc; and a prosthesis (3, 103, 203, 303) attachable in a secure coupling position to the anchoring body (2, 102) and adapted for retaining or replacing the nucleus pulposus in an interior space of an outer annulus of the intervertebral disc, the anchoring body supporting and arranging in the cited coupling position the prosthesis such that the prosthesis is oriented to in a direction toward and through a hole in the outer annulus, the prosthesis comprising at least one active portion (4) adapted to assume and maintain a first placement shape (A) suitable for permitting the active portion to be inserted into and through the hole in the outer annulus during a placement thereof into the interior space of the outer annulus, and at least a second operative shape (B) suitable for at least partially occluding the hole in the ouType: ApplicationFiled: March 12, 2014Publication date: January 21, 2016Inventors: Marc SERRAHIMA TORNEL, Salvador LLAS VARGAS, Ana RODRIGUEZ ALONSO, Montserrat CHARLES-HARRIS FERRER, Lluis CHICO ROCA, Pablo CLAVEL LARIA
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Publication number: 20150353954Abstract: The invention provides a method for controlling Huanglongbing (HLB) disease of citrus plants through expressing genes encoding synthases for sesquiterpenes such as ?-caryophyllene, and ?-copaene, and combinations thereof, in citrus plants. Methods of controlling HLB comprising applying at least one purified sesquiterpene, which repels Diaphorina citri and/or Tryoza erytrae psyllid insects, so as to control the HLB disease of citrus plants, are also disclosed.Type: ApplicationFiled: June 8, 2015Publication date: December 10, 2015Inventors: Berta ALQUEZAR GARCÍA, Ana RODRIGUEZ BAIXAULI, Josep PERIS RODRIGO, Leandro PEÑA GARCÍA, Andréia ENRIQUE, Marcelo PEDREIRA DE MIRANDA, Pedro Takao YAMAMOTO, Marcel Bellato SPÓSITO, Nelson Arno WULFF, Diva do Carmo TEIXEIRA, Antonio Juliano AYRES, Newton Cavalcanti DE NORONHA, JR., José Maurício Simões BENTO, José Roberto POSTALI PARRA
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Publication number: 20150353955Abstract: The invention provides a method for controlling Huanglongbing (HLB) disease of citrus plants through expressing genes encoding synthases for sesquiterpenes such as ?-caryophyllene, and ?-copaene, and combinations thereof, in citrus plants. Methods of controlling HLB comprising applying at least one purified sesquiterpene, which repels Diaphorina citri and/or Tryoza erytrae psyllid insects, so as to control the HLB disease of citrus plants, are also disclosed.Type: ApplicationFiled: June 8, 2015Publication date: December 10, 2015Inventors: Berta ALQUEZAR GARCÍA, Ana RODRIGUEZ BAIXAULI, Josep PERIS RODRIGO, Leandro PEÑA GARCÍA, Andréia ENRIQUE, Marcelo PEDREIRA DE MIRANDA, Pedro Takao YAMAMOTO, Marcel Bellato SPÓSITO, Nelson Arno WULFF, Diva do Carmo TEIXEIRA, Antonio Juliano AYRES, Newton Cavalcanti DE NORONHA, JR., José Maurício Simões BENTO, José Roberto POSTALI PARRA, Mateus de Almeida SANTOS, Viviani Vieira MARQUES, André Gustavo Corrêa SIGNORETTI, Rodrigo Facchini MAGNANI
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Publication number: 20150247138Abstract: Virion-associated peptidoglycan hydrolases have a potential as antimicrobial agents due to their ability to lyse Gram positive bacteria on contact. Full-length HydH5, a virion-associated peptidoglycan hydrolase from the Staphylococcus aureus bacteriophage vB_SauS-phi-IPLA88, and two truncated derivatives, containing only the CHAP domain, exhibited high lytic activity against live S. aureus cells. Three different fusion proteins were created and showed higher staphylolytic activity than the parental enzyme or its deletion construct. Parental and fusion proteins lysed S. aureus cells in zymograms, plate lysis and turbidity reduction assays. In plate lysis assays, HydH5 and its derivative fusions lysed bovine and human S. aureus, S. aureus MRSA N315 strain, and human Staphylococcus epidermidis strains.Type: ApplicationFiled: February 12, 2015Publication date: September 3, 2015Inventors: David M. Donovan, Lorena Rodriguez Rubio, Beatriz Martinez Fernandez, Ana Rodriguez, Pilar Garcia Suarez
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Patent number: 9078448Abstract: The invention provides a method for controlling Huanglongbing (HLB) disease of citrus plants through expressing genes encoding synthases for sesquiterpenes such as ?-caryophyllene, and ?-copaene, and combinations thereof, in citrus plants. Methods of controlling HLB comprising applying at least one purified sesquiterpene, which repels Diaphorina citri and/or Tryoza erytrae psyllid insects, so as to control the HLB disease of citrus plants, are also disclosed.Type: GrantFiled: October 26, 2010Date of Patent: July 14, 2015Assignees: Fundo de Defesa da Citricultura—Fundecitrus, Instituto Valenciano de Investigaciones AgrariasInventors: Berta Alquezar García, Ana Rodriguez Baixauli, Josep Peris Rodrigo, Leandro Peña García, Andréia Enrique, Marcelo Pedreira De Miranda, Pedro Takao Yamamoto, Marcel Bellato Spósito, Nelson Arno Wulff, Diva do Carmo Teixeira, Antonio Juliano Ayres, Newton Cavalcanti De Noronha, Jr., José Maurício Simões Bento, José Roberto Postali Parra
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Patent number: 8986695Abstract: Virion-associated peptidoglycan hydrolases have a potential as antimicrobial agents due to their ability to lyse Gram positive bacteria on contact. Full-length HydH5, a virion-associated peptidoglycan hydrolase from the Staphylococcus aureus bacteriophage vB_SauS-phi-IPLA88, and two truncated derivatives, containing only the CHAP domain, exhibited high lytic activity against live S. aureus cells. Three different fusion proteins were created and showed higher staphylolytic activity than the parental enzyme or its deletion construct. Parental and fusion proteins lysed S. aureus cells in zymograms, plate lysis and turbidity reduction assays. In plate lysis assays, HydH5 and its derivative fusions lysed bovine and human S. aureus, S. aureus MRSA N315 strain, and human Staphylococcus epidermidis strains.Type: GrantFiled: November 17, 2011Date of Patent: March 24, 2015Assignee: The United States of America, as represented by The Secretary of AgricultureInventors: David M. Donovan, Lorena Rodriguez Rubio, Beatriz Martinez Fernandez, Ana Rodriguez, Pilar Garcia Suarez
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Patent number: 8785725Abstract: The invention consists in modifying the levels of accumulation and emission of monoterpenes and sesquiterpenes in citrus as a mechanism to achieve systemic resistance against pathogens or repellency against pests. The alteration of the content of d-limonene and other terpenes is achieved by genetic transformation via the introduction of a gene that encodes an enzyme with d-limonene synthase activity, from a citrus fruit or plant or from another living organism, in antisense or RNAi (RNA interference) configuration. Genetic modification is achieved either by Agrobacterium tumefaciens or any other method of genetic transformation of plants from protoplasts or explants. The construction is incorporated in citrus genotypes or related genera of the family Rutaceae in order to reduce the levels of accumulation and emission of the monoterpene and precursor compounds and/or derivatives, either of leaves or flowers and/or fruit.Type: GrantFiled: November 15, 2010Date of Patent: July 22, 2014Assignee: Institute Valenciano de Investigaciones AgrariasInventors: Ana Rodriguez Baixauli, Magdalena Cervera Ocaña, Takehiko Shimada, Lluis Palou Vall, Lorenzo Zacarias Garcia, Maria Milagros Lopez Gonzalez, Leandro Peña Garcia, Pedro Castañera Domínguez, Victoria San Andres Aura, Maria Jesús Rodrigo Esteve, Ana Redondo Puntonet
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Publication number: 20140045860Abstract: The invention relates to a compound of Formula I or a pharmaceutically acceptable ester, salt, prodrug or metabolite thereof;Type: ApplicationFiled: August 13, 2013Publication date: February 13, 2014Applicants: NEW YORK UNIVERSITY, THE BROAD INSTITUTE, INC.Inventors: Leigh C. Carmody, Ana Rodriguez, Esther Bettiol, Michelle Palmer, Andrew Germain, Benito Munoz, Sivaraman Dandapani, Michael Foley
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Publication number: 20130296316Abstract: Disclosed is the use of mammalian target of rapamycin (mTOR) and/or phosphoinositide-3-kinase (PI3K) inhibitors as antiparasitic drugs, particularly in those parasitic infections caused by trypanosomatid parasites {Trypanosoma sp. and Leishmania sp.). These inhibitors are useful as trypanocides.Type: ApplicationFiled: July 11, 2011Publication date: November 7, 2013Inventors: Michael P. Pollastri, Miguel Navarro, Stephen Beverley, Ana Rodriguez
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Patent number: 8563610Abstract: This invention relates to the identification and treatment of the effects of products derived from oxidative pathways for polyunsaturated fatty acid (PUFA) metabolism, i.e., oxidative stress in a patient by monitoring the metabolism of DHA or by administering DHA.Type: GrantFiled: February 4, 2011Date of Patent: October 22, 2013Assignees: Rutgers, The State of New Jersey, Rowan UniversityInventors: Thomas P. Stein, Bernd W. Spur, George H. Lambert, Sue X. Ming, Ana Rodriguez
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Publication number: 20130129697Abstract: Virion-associated peptidoglycan hydrolases have a potential as antimicrobial agents due to their ability to lyse Gram positive bacteria on contact. Full-length HydH5, a virion-associated peptidoglycan hydrolase from the Staphylococcus aureus bacteriophage vB_SauS-phi-IPLA88, and two truncated derivatives, containing only the CHAP domain, exhibited high lytic activity against live S. aureus cells. Three different fusion proteins were created and showed higher staphylolytic activity than the parental enzyme or its deletion construct. Parental and, fusion proteins lysed S. aureus cells in zymograms, plate lysis and turbidity reduction assays. In plate lysis assays, HydH5 and its derivative fusions lysed bovine and human S. aureus, S. aureus MRSA N315 strain, and human Staphylococcus epidermidis strains.Type: ApplicationFiled: November 17, 2011Publication date: May 23, 2013Inventors: David M. Donovan, Lorena Rodriguez Rubio, Beatriz Martinez Fernandez, Ana Rodriguez, Pilar Garcia Suarez