Patents by Inventor Ana VILLAR GAREA

Ana VILLAR GAREA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INSULIN CONJUGATES
    Publication number: 20220048968
    Abstract: The present invention relates to a conjugate comprising a sulfonamide of formula (I) and an active pharmaceutical ingredient such as an insulin analog comprising at least one mutation relative to the parent insulin, wherein the insulin analog comprises a mutation at position B16 which is substituted with a hydrophobic amino acid and/or a mutation at position B25 which is substituted with a hydrophobic amino acid. The present invention further relates to a sulfonamide of formula (A). Moreover, the present invention relates to an insulin analog comprising at least one mutation relative to the parent insulin.
    Type: Application
    Filed: May 25, 2021
    Publication date: February 17, 2022
    Inventors: Maria MENDEZ PEREZ, Nils RACKELMANN, Laurent BIALY, Stefan GUESSREGEN, Martin WILL, Thomas BOEHME, Ana VILLAR GAREA, Marcus Hermann KORN, Melissa BESENIUS, Jens RIEDEL, Ulrich WERNER, Michael PODESCHWA
  • Insulin conjugates
    Patent number: 11098102
    Abstract: The present invention relates to a conjugate comprising a sulfonamide of formula (I) and an active pharmaceutical ingredient such as an insulin analog comprising at least one mutation relative to the parent insulin, wherein the insulin analog comprises a mutation at position B16 which is substituted with a hydrophobic amino acid and/or a mutation at position B25 which is substituted with a hydrophobic amino acid. The present invention further relates to a sulfonamide of formula (A). Moreover, the present invention relates to an insulin analog comprising at least one mutation relative to the parent insulin.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: August 24, 2021
    Assignee: SANOFI
    Inventors: Maria Mendez Perez, Nils Rackelmann, Laurent Bialy, Stefan Guessregen, Martin Will, Thomas Boehme, Ana Villar Garea, Marcus Hermann Korn, Melissa Besenius, Jens Riedel, Ulrich Werner, Michael Podeschwa
  • INSULIN CONJUGATES
    Publication number: 20200181223
    Abstract: The present invention relates to a conjugate comprising a sulfonamide of formula (I) and an active pharmaceutical ingredient such as an insulin analog comprising at least one mutation relative to the parent insulin, wherein the insulin analog comprises a mutation at position B16 which is substituted with a hydrophobic amino acid and/or a mutation at position B25 which is substituted with a hydrophobic amino acid. The present invention further relates to a sulfonamide of formula (A). Moreover, the present invention relates to an insulin analog comprising at least one mutation relative to the parent insulin.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 11, 2020
    Inventors: Maria MENDEZ PEREZ, Nils RACKELMANN, Laurent BIALY, Stefan GUESSREGEN, Martin WILL, Thomas BOEHME, Ana VILLAR GAREA, Marcus Hermann KORN, Melissa BESENIUS, Jens RIEDEL, Ulrich WERNER, Michael PODESCHWA