Abstract: Process control of continuous production of biomolecules is a major challenge due to complex nature of processes and time scales of operations involved. Availability of key process variables in real-time is one of main requirements. This disclosure relates to a processor implemented method of controlling a continuous bioprocessing plant which includes at least one of: receiving, an input data associated with one or more equipments; generating, by a recipe builder, a sequence of unit operations to determine at least one job order based on the at least input data; obtaining, a control decision associated with a control parameter based on the at least one job order; communicating, via the middleware, the control decision associated with the control parameter to the PLC; and executing, by a control system of the PLC, the control decision on a unit equipment to control: (i) a continuous bioprocessing train, and (ii) an individual unit operation.

Abstract: The present invention utilizes a pattern extraction methodology to elucidate significant patterns and mathematical relationships that exist between and among pluralities of two-dimensional sample data sets of the same data type. In one instance, the present invention analyzes multi-sample, two-dimensional mass spectroscopy data, while in an alternate instance, another user-specified, preset, or automatically determined data type, modality, submodality, etc., is analyzed.

Abstract: The present invention utilizes a pattern extraction methodology to elucidate significant patterns and mathematical relationships that exist between and among pluralities of two-dimensional sample data sets of the same data type. In one instance, the present invention analyzes multi-sample, two-dimensional mass spectroscopy data, while in an alternate instance, another user-specified, preset, or automatically determined data type, modality, submodality, etc., is analyzed.

Abstract: In an embodiment, a two-dimensional, grey-scale image is the data type to be analyzed, and a plurality of pixels which compose an image, are referred to as a data element. The image is analyzed and each pixel is assigned a value, for example from 0-255; in one embodiment, the values are stored in a system cache or a data store. A new image file is created and configured to be the same size as the original image and capable of storing a numerical representation of each pixel. An algorithmic analysis is performed on the data stored from the grey-scale image, resulting in a new value being stored in the new image file. The resulting image is created from these values and represents a new transformed image.