Patents by Inventor Anand Apte

Anand Apte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160108114
    Abstract: The present invention pertains to methods of inhibiting angiogenesis (e.g., ocular angiogenesis choroidal neovasculariztion) in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of 5 oxidative peptide modification of polyunsaturated fatty acids (PUFA) in the individual, and administration of the agent inhibits angiogenesis in the individual.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 21, 2016
    Inventors: John W. Crabb, Robert G. Salomon, Bela Anand-Apte, Quteba Ebrahem, Kutralanathan Renganathan
  • Publication number: 20150302025
    Abstract: A system and a method are disclosed for pre-seeding data to backup servers and determining servers for additional backups. Backup data is received from a client device through a first backup request and sent to a primary server for storage. Additional backup data from a second backup request is received. After the initial backup data is stored on the primary server and pre-seeded by the primary server on a secondary server, a status of backup servers associated with the client device is received. The backup servers include the primary server and can include the secondary server. Responsive to the status indicating availability of a server in the backup servers, a recipient server is identified from the backup servers and the additional backup data is sent to the identified recipient server.
    Type: Application
    Filed: April 8, 2015
    Publication date: October 22, 2015
    Applicant: DRUVA INC.
    Inventors: Anand Apte, Somesh Jain, Milind Borate, Shekhar S. Deshkar
  • Patent number: 8996467
    Abstract: A distributed, cloud-based storage system provides a reliable, deduplicated, scalable and high performance backup service to heterogeneous clients that connect to it via a communications network. The distributed cloud-based storage system guarantees consistent and reliable data storage while using structured storage that lacks ACID compliance. Consistency and reliability are guaranteed using a system that includes: 1) back references from shared objects to referring objects, 2) safe orders of operation for object deletion and creation, 3) and simultaneous access to shared resources through sub-resources.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: March 31, 2015
    Assignee: Druva Inc.
    Inventors: Anand Apte, Faisal Puthuparackat, Jaspreet Singh, Milind Borate, Shekhar S. Deshkar
  • Patent number: 8700634
    Abstract: A deduplicated data storage system provides high performance storage to heterogeneous clients that connect to it via a communications network. The deduplicated data storage system provides fast access to deduplication data by caching the most frequently accessed deduplication data in a hyperindex. Updates to the non-cached deduplication data are serialized by use of a store queue and hold queue.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: April 15, 2014
    Assignee: Druva Inc.
    Inventors: Anand Apte, Jaspreet Singh, Milind Borate, Shekhar S. Deshkar
  • Publication number: 20130173627
    Abstract: A deduplicated data storage system provides high performance storage to heterogeneous clients that connect to it via a communications network. The deduplicated data storage system provides fast access to deduplication data by caching the most frequently accessed deduplication data in a hyperindex. Updates to the non-cached deduplication data are serialized by use of a store queue and hold queue.
    Type: Application
    Filed: December 29, 2011
    Publication date: July 4, 2013
    Inventors: Anand Apte, Jaspreet Singh, Milind Borate, Shekhar S. Deshkar
  • Publication number: 20130173553
    Abstract: A distributed, cloud-based storage system provides a reliable, deduplicated, scalable and high performance backup service to heterogeneous clients that connect to it via a communications network. The distributed cloud-based storage system guarantees consistent and reliable data storage while using structured storage that lacks ACID compliance. Consistency and reliability are guaranteed using a system that includes: 1) back references from shared objects to referring objects, 2) safe orders of operation for object deletion and creation, 3) and simultaneous access to shared resources through sub-resources.
    Type: Application
    Filed: December 29, 2011
    Publication date: July 4, 2013
    Inventors: Anand Apte, Faisal Puthuparackat, Jaspreet Singh, Milind Borate, Shekhar S. Deshkar
  • Patent number: 8431396
    Abstract: A purified polypeptide includes about 10 to about 40 amino acids and has an amino acid sequence corresponding to a portion of SEQ ID NO: 2. The polypeptide can inhibit binding of VEGF to VEGFR2 of cells that express VEGFR2.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: April 30, 2013
    Assignee: The Cleveland Clinic Foundation
    Inventor: Bela Anand-Apte
  • Publication number: 20120230996
    Abstract: The present invention pertains to methods of inhibiting angiogenesis (e.g., ocular angiogenesis choroidal neovasculariztion) in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of 5 oxidative peptide modification of polyunsaturated fatty acids (PUFA) in the individual, and administration of the agent inhibits angiogenesis in the individual.
    Type: Application
    Filed: February 9, 2012
    Publication date: September 13, 2012
    Applicant: The Cleveland Clinic Foundation and Case Western Reserve University
    Inventors: John W. Crabb, Robert G. Salomon, Bela Anand-Apte, Quteba Ebrahem, Kutralanathan Renganathan
  • Patent number: 8137991
    Abstract: The present invention pertains to methods of inhibiting angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of oxidative peptide modification of polyunsaturated fatty acids (PUFA) in the individual, and administration of the agent inhibits angiogenesis in the individual. In one embodiment, the invention is directed to methods of inhibiting ocular angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits the angiogenic activity of one or more CEP protein adducts wherein administration of the. agent inhibits ocular angiogenesis in the individual.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: March 20, 2012
    Assignees: The Cleveland Clinic Foundation, Case Western Reserve University
    Inventors: John W. Crabb, Robert G. Salomon, Bela Anand-Apte, Quteba Ebrahem, Kutralanathan Reganathan
  • Patent number: 7908302
    Abstract: A method, computer program product, and apparatus providing a means to split files and to merge files without the need for duplicating all of the data of the original files is disclosed.
    Type: Grant
    Filed: September 17, 2004
    Date of Patent: March 15, 2011
    Assignee: Symantec Operating Corporation
    Inventors: Sree Hari Nagaralu, Sunder Phani Kumar, Anand Apte
  • Publication number: 20100143380
    Abstract: The present invention pertains to methods of inhibiting angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits one or more CEP protein adducts wherein the angiogenesis is the result of oxidative peptide modification of polyunsaturated fatty acids (PUFA) in the individual, and administration of the agent inhibits angiogenesis in the individual. In one embodiment, the invention is directed to methods of inhibiting ocular angiogenesis in an individual in need thereof comprising administering to the individual an agent that inhibits the angiogenic activity of one or more CEP protein adducts wherein administration of the. agent inhibits ocular angiogenesis in the individual.
    Type: Application
    Filed: July 23, 2007
    Publication date: June 10, 2010
    Inventors: John W. Crabb, Robert G. Salomon, Bela Anand-Apte, Quteba Ebrahem, Kutralanathan Renganathan
  • Publication number: 20100099611
    Abstract: A purified polypeptide includes about 10 to about 40 amino acids and has an amino acid sequence corresponding to a portion of SEQ ID NO: 2. The polypeptide can inhibit binding of VEGF to VEGFR2 of cells that express VEGFR2.
    Type: Application
    Filed: February 29, 2008
    Publication date: April 22, 2010
    Inventor: Bela Anand-Apte
  • Publication number: 20070202094
    Abstract: Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF receptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VEGF binding to VEGF receptor 1 (VEGFR1/Flt-1).
    Type: Application
    Filed: January 16, 2007
    Publication date: August 30, 2007
    Inventor: Bela Anand-Apte
  • Patent number: 7183256
    Abstract: Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF recptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VEGF binding to VEGF receptor 1 (VEGFR1/Flt-1).
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: February 27, 2007
    Assignee: Cleveland Clinic Foundation
    Inventor: Bela Anand-Apte
  • Publication number: 20040224398
    Abstract: Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF recptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VEGF binding to VEGF receptor 1 (VEGFR1/Flt-1).
    Type: Application
    Filed: March 19, 2004
    Publication date: November 11, 2004
    Applicant: The Cleveland Clinic Foundation
    Inventor: Bela Anand-Apte