Patents by Inventor Anand Divakaran

Anand Divakaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING LIVER DISEASE
    Publication number: 20250114355
    Abstract: This document relates to methods and materials for treating liver diseases (e.g., an alcohol-induced liver disease (ALD) such as alcoholic hepatitis (AH)). For example. one or more inhibitors of a bromodomain-containing protein 4 (BRD4) polypeptide can be administered to a mammal (e.g., a human) having a liver disease (e.g., an ALD such as AH) to treat the mammal.
    Type: Application
    Filed: May 9, 2022
    Publication date: April 10, 2025
    Inventors: Vijay H. Shah, Sheng Cao, Mengfei Liu, Joseph Topczewski, William C.K. Pomerantz, Angela S. Carlson, Huarui Cui, Anand Divakaran
  • THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20240294503
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, A, B, D, E, F and G have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as bromodomain inhibitors.
    Type: Application
    Filed: April 18, 2024
    Publication date: September 5, 2024
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Joseph J. Topczewski, William C.K. Pomerantz, Angela S. Carlson, Huarui Cui, Anand Divakaran
  • Therapeutic compounds and methods of use thereof
    Patent number: 11987572
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, A, B, D, E, F and G have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as bromodomain inhibitors.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: May 21, 2024
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Joseph J. Topczewski, William C. K. Pomerantz, Angela S. Carlson, Huarui Cui, Anand Divakaran
  • SELECTIVE BRD4-DEGRADER MOLECULES
    Publication number: 20240051938
    Abstract: The invention provides a compound of formula (I): or a salt thereof wherein B, L, and X have any of the values defined in the specification, as well as compositions comprising a compound of formula (I) or a salt thereof. The compounds selectively degrade BRD4, and are useful as to treat cancer and inflammatory conditions.
    Type: Application
    Filed: July 31, 2023
    Publication date: February 15, 2024
    Applicant: Regents of the University of Minnesota
    Inventors: Huarui Cui, Anand Divakaran, Daniel A. Harki, William C. K. Pomerantz
  • THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20200377474
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, A, B, D, E, F and G have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as bromodomain inhibitors.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 3, 2020
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Joseph J. Topczewski, William C.K. Pomerantz, Angela S. Carlson, Huarui Cui, Anand Divakaran