Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.

Abstract: A method for monitoring driver alertness in a vehicle is disclosed. Image data representing images of an eye of a driver are obtained, the images having been captured while the driver is operating the vehicle. An eye openness measure of the eye of the driver is computed, based on the image data. A determination is made that the driver is in an unsafe state for driving based on the eye openness measure, and an alert is generated, while the driver is operating the vehicle, based on determining that the driver is in the unsafe state.

Abstract: The disclosure provides noninvasive methods for the in vivo identification and characterization of various immune cell populations in human skin. The methods of the disclosure employ advanced imaging systems based on nonlinear optical microscopy to generate images that are analyzed to detect, identify, differentiate, and quantify immune cell populations in human skin by their morphological, metabolic and behavioral signatures.

Abstract: A method for controlling a powertrain of an electric vehicle. The method includes receiving a torque demand signal. Thereafter, a future power loss within the powertrain is estimated as a function of a torque distribution between at least two electric traction machines of the powertrain. Alternatively or additionally the loss can be estimated as a function of a free rolling state of at least one of the electric machines. Subsequently, a torque distribution between the electric traction machines is determined and/or a free rolling state of at least one of the electric machines is determined which minimizes the future power loss. Moreover, a corresponding data processing device, a corresponding computer program and a corresponding computer-readable medium are presented. Moreover, a powertrain for an electric vehicle is described. The powertrain includes such a data processing device and at least two electric traction machines and/or a clutch device.

Abstract: A method for monitoring driver alertness in a vehicle is disclosed. Image data representing images of an eye of a driver are obtained, the images having been captured while the driver is operating the vehicle. An eye openness measure of the eye of the driver is computed, based on the image data. A determination is made that the driver is in an unsafe state for driving based on the eye openness measure, and an alert is generated, while the driver is operating the vehicle, based on determining that the driver is in the unsafe state.

Abstract: A computer-implemented method may comprise iteratively receiving a tag selected by a user of the computing device; storing the received tag in a memory of a computing device; associating, by a processor of the computing device, the stored tag with at least one digital asset stored in the computing device or stored in a remote storage of the user that is accessible over a computer network; and generating, by the processor, a graphical representation of the received tag. A search request may then be received, via the user interface, the search request comprising an expression including at least one of the tags stored in the memory of the computing device. The processor may then identify at least one of the user's digital assets that is associated with at least one of the tags in the search request.

Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.

Abstract: A computer-implemented method may comprise iteratively receiving a tag selected by a user of the computing device; storing the received tag in a memory of a computing device; associating, by a processor of the computing device, the stored tag with at least one digital asset stored in the computing device or stored in a remote storage of the user that is accessible over a computer network; and generating, by the processor, a graphical representation of the received tag. A search request may then be received, via the user interface, the search request comprising an expression including at least one of the tags stored in the memory of the computing device. The processor may then identify at least one of the user's digital assets that is associated with at least one of the tags in the search request.

Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.

Abstract: Disclosed is a technique for managing access by a portable device to an in-vehicle router system (IVRS). The IVRS determines network access privilege of the portable device located within the vehicle. The portable device determines whether it is connected to a wireless access point (AP) of the IVRS or a rogue network. The portable device transmits a first token to the wireless AP, via a first communication link implementing a first protocol stack, to prompt the wireless AP to reply with a second token. The portable device receives the second token via a second communication link implementing a second protocol stack different than the first protocol stack between the portable device and the IVRS. The portable device determines whether the second token matches the first token. If the second token is determined to match the first token, the portable device authenticates the wireless AP.

Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.

Abstract: Disclosed is a technique for managing communications of portable devices within a vehicle through an in-vehicle router system. The in-vehicle router system includes a plurality of out-of-band interfaces used to determine a user type associated with a portable device used to manage a connection with a wireless access point. The out-of-band interface receives a query from a portable device via a first communication link. The query includes identifying information of the portable device and a request for network credentials to a second communication link with a wireless access point. A user type is determined based on a location of the out-of-band interface and a unique identifier. Network credentials associated with the determined user type are retrieved. The network credentials are provided to the portable device via the first communication link. Access to the second communication link is restricted based on the user type and/or vehicle status information.

Abstract: A computer-implemented method may comprise iteratively receiving a tag selected by a user of the computing device; storing the received tag in a memory of a computing device; associating, by a processor of the computing device, the stored tag with at least one digital asset stored in the computing device or stored in a remote storage of the user that is accessible over a computer network; and generating, by the processor, a graphical representation of the received tag. A search request may then be received, via the user interface, the search request comprising an expression including at least one of the tags stored in the memory of the computing device. The processor may then identify at least one of the user's digital assets that is associated with at least one of the tags in the search request.

Abstract: Disclosed is a technique for managing access by a portable device to an in-vehicle router system (IVRS). The IVRS determines network access privilege of the portable device located within the vehicle. The portable device determines whether it is connected to a wireless access point (AP) of the IVRS or a rogue network. The portable device transmits a first token to the wireless AP, via a first communication link implementing a first protocol stack, to prompt the wireless AP to reply with a second token. The portable device receives the second token via a second communication link implementing a second protocol stack different than the first protocol stack between the portable device and the IVRS. The portable device determines whether the second token matches the first token.

Abstract: Disclosed is a technique for managing communications of portable devices within a vehicle through an in-vehicle router system. The in-vehicle router system includes a plurality of out-of-band interfaces used to determine a user type associated with a portable device used to manage a connection with a wireless access point. The out-of-band interface receives a query from a portable device via a first communication link. The query includes identifying information of the portable device and a request for network credentials to a second communication link with a wireless access point. A user type is determined based on a location of the out-of-band interface and a unique identifier. Network credentials associated with the determined user type are retrieved. The network credentials are provided to the portable device via the first communication link. Access to the second communication link is restricted based on the user type and/or vehicle status information.

Abstract: The present invention relates to a method and system for recommending fitting footwear. The method includes receiving, by a footwear recommendation system, a plurality of still images associated with at least one foot of a user. At least one of the still images includes information of a standard reference object placed proximate to the at least one foot of the user. The still images are processed to generate a digital geometric profile representing the at least one foot of the user. Set of foot measurements is extracted from the digital geometric profile to classify the digital geometric profile into foot type data. The digital geometric profile and the foot type data together are stored as a foot geometric profile. At least one fitting footwear is identified for the user based on the foot geometric profile. Moreover, display of the at least one fitting footwear on the user device is initiated.

Abstract: Disclosed is a technique for managing access by a portable device to an in-vehicle router system (IVRS). The IVRS determines network access privilege of the portable device located within the vehicle. The portable device determines whether it is connected to a wireless access point (AP) of the IVRS or a rogue network. The portable device transmits a first token to the wireless AP, via a first communication link implementing a first protocol stack, to prompt the wireless AP to reply with a second token. The portable device receives the second token via a second communication link implementing a second protocol stack different than the first protocol stack between the portable device and the IVRS. The portable device determines whether the second token matches the first token. If the second token is determined to match the first token, the portable device authenticates the wireless AP.

Abstract: Disclosed is a technique for managing communications of portable devices within a vehicle through an in-vehicle router system. The in-vehicle router system includes a plurality of out-of-band interfaces used to determine a user class associated with a portable device used to manage a connection with a wireless access point. The out-of-band interface receives a query from a portable device via a first communication link. The query includes identifying information of the portable device and a request for network credentials to a second communication link with a wireless access point. A user type is determined based on a location of the out-of-band interface and a unique identifier. Network credentials associated with the determined user type are retrieved. The network credentials are provided to the portable device via the first communication link. Access to the second communication link is restricted based on the user type and/or vehicle status information.

Abstract: The present invention provides methods and compositions for reducing pigmentation.

Abstract: A method and apparatus for prediction of community reaction to a post for an online social community is disclosed. The method comprises receiving a proposed post as input to a generated prediction model prior to the proposed post being posted to an online social community; predicting a community reaction to the proposed post using the prediction model; and displaying the predication, wherein the prediction comprises a sentiment score and at least one of a number of responses, a number of responders to the post, a longevity of the post, or a half-life of the post.