Patents by Inventor Anand K. Agarwal
Anand K. Agarwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10849540Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range.Type: GrantFiled: March 11, 2014Date of Patent: December 1, 2020Assignee: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Do Young Yoon, Boren Lin, Hamid Feyzizarnagh
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Patent number: 10828171Abstract: An intervertebral cage includes a plurality of segments that are connected together by one or more members formed from a shape memory alloy material such that the segments are automatically moved from an initial orientation before implantation/insertion in an intervertebral space to an expanded orientation after implantation/insertion in the intervertebral space. Each of the plurality of segments may have a plurality of passageways or recesses formed therethrough, and wherein a wire formed from a shape memory alloy material extends through each of the plurality of passageways or recesses. The member may be formed from a shape memory alloy material that demonstrates shape memory effects and superelasticity properties, such as nitinol.Type: GrantFiled: July 18, 2014Date of Patent: November 10, 2020Assignee: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Aakash Agarwal, David Dick
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Publication number: 20200061235Abstract: Macroporous cement compositions, methods of making the same, and methods of using the same, are described.Type: ApplicationFiled: November 1, 2019Publication date: February 27, 2020Applicant: The University of ToledoInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel, Sameh Saleh
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Patent number: 10478239Abstract: A pedicle screw assembly includes a threaded shank portion formed from a polymer material and a head assembly. The head assembly includes a tulip having extending arms, the tulip engaging a reaction bar such that loads applied to the pedicle screw assembly can be transferred to another pedicle screw assembly in order to immobilize a section of a spinal column.Type: GrantFiled: March 10, 2014Date of Patent: November 19, 2019Assignee: Spinal Balance, Inc.Inventors: Anand K. Agarwal, Aakash Agarwal
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Patent number: 10478315Abstract: A metering delivery apparatus for injecting bone graft cement includes a body portion, a material containment vessel, an actuator, and a control unit. The body portion includes a drive housing that supports an actuator drivetrain and receiver end that supports the material containment vessel. The actuator has a first end connected to the actuator drivetrain and a second end that supports a moveable portion of the vessel to dispense material in the vessel and a retracting movement that relieves pressure applied to the material. The control unit receives actuator parameter inputs and includes a sensor to detect a signal of at least one of a pressure level and a time period. The sensor provides the detected signal to the control unit such that the control unit operates the actuator between the dispensing and retracting movements based on the detected signal and the actuator parameter inputs.Type: GrantFiled: June 24, 2015Date of Patent: November 19, 2019Assignee: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Joel M. Gerber, Aakash Agarwal
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Patent number: 10349994Abstract: Described herein are bone graft material (BGM) delivery devices having a tray configured to provide a mixing and/or holding area for BGM to substantially prevent BGM from inadvertently being delivered to an unacceptable surgical site.Type: GrantFiled: March 31, 2015Date of Patent: July 16, 2019Assignee: The University of ToledoInventors: Hossein Elgafy, Anand K. Agarwal, Vijay K. Goel, Narjes Momeni Shahraki, Amey V. Kelkar
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Patent number: 10342893Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass.Type: GrantFiled: January 31, 2013Date of Patent: July 9, 2019Assignee: The University of ToledoInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
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Publication number: 20190150992Abstract: An interspinous stabilization device is provided that more evenly distributes loads throughout the adjacent vertebrae than known interspinous stabilization devices, and further can readily compensate for graft settling so as to maintain continued axial loading of the graft material.Type: ApplicationFiled: January 28, 2019Publication date: May 23, 2019Applicant: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Aakash Agarwal
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Patent number: 10188434Abstract: This invention relates to an improved structure for an interspinous stabilization device that more evenly distributes loads throughout the adjacent vertebrae than known interspinous stabilization devices, and further readily compensates for graft settling so as to maintain continued axial loading of the graft. More specifically, this invention relates to a medical device that helps in performing a spinal fusion procedure by holding the bone graft in place and stabilizing the facet screw by a plate that is attached to it. The invention also performs a dynamic function that compensates for settling of the bone graft over time. This dynamic function may, if desired, be enhanced by a movement-limiting mechanism that allows extension but not flexion such that the bone graft fusion remains in contact and fusion takes place.Type: GrantFiled: February 19, 2013Date of Patent: January 29, 2019Assignee: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Aakash Agarwal
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Publication number: 20180369445Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.Type: ApplicationFiled: August 30, 2018Publication date: December 27, 2018Applicant: The University of ToledoInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
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Publication number: 20180271423Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The SAM layer may include an anti-fouling agent. The transducer component includes an electrode (or set of electrodes that includes a working electrode) and microprocessor configured to screen noise and to pick up a detectable signal, such as impedance change at a very low frequency range.Type: ApplicationFiled: October 6, 2016Publication date: September 27, 2018Applicant: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Dong-Shik Kim, Boren Lin
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Patent number: 10064972Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass.Type: GrantFiled: January 31, 2013Date of Patent: September 4, 2018Assignee: The University of ToledoInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
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Patent number: 10052403Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.Type: GrantFiled: March 24, 2016Date of Patent: August 21, 2018Assignee: THE UNIVERSITY OF TOLEDOInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
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Patent number: 10052402Abstract: Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.Type: GrantFiled: March 23, 2016Date of Patent: August 21, 2018Assignee: THE UNIVERSITY OF TOLEDOInventors: Sarit B. Bhaduri, Huan Zhou, Anand K. Agarwal, Vijay K. Goel
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Patent number: 9968377Abstract: A growth rod distraction system a domino having first and second bores provided therein. First and second spinal rods are respectively disposed within the first and second bores for movement relative to the domino. First and second spur gears are disposed within the domino and respectively cooperate with the first and second growth rods such that rotation of the spur gears causes axial movements of the growth rods relative to the domino. The spinal rods may be formed either from a flexible polymer material (such as a PEEK, carbon fiber PEEK, PEAK, or similar medical grade polymer material) or a hybrid combination of such flexible polymer material and a metallic material (such as nitinol or similar medical grade metallic material). The spinal rods can also be used for fusion or non-fusion surgery of the spine to stabilize two or more vertebrae.Type: GrantFiled: March 17, 2014Date of Patent: May 15, 2018Assignee: Spinal Balance, Inc.Inventor: Anand K. Agarwal
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Patent number: 9956008Abstract: A spinal fixation device includes a device body configured for implantation in a human body and a clamp that is formed from shape memory material and attached to the device body.Type: GrantFiled: April 25, 2014Date of Patent: May 1, 2018Assignee: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, John R. D'Onofrio, Nathaniel E. DuBois, Jared R. Pack, David J. Taylor
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Patent number: 9808299Abstract: In a first broad aspect, there is provided herein a bioactive device and system for fusion between two bones, two parts of a bony joint, or a bony defect, such as of the spine. The fusion device includes a screw having a head and a threaded shaft. The fusion device also includes a bone dowel having an internal bore of which at least a distal portion is threaded to engage the threads of the screw shaft. The bone dowel is made of a bone-like, biocompatible, or allograft material to provide a layer of bone-like, biocompatible, or allograft material between the screw and the spinal bone. The device is generally coaxial and is further described in the drawings and description herein.Type: GrantFiled: January 31, 2013Date of Patent: November 7, 2017Assignee: The University of ToledoInventors: Vijay K. Goel, Anand K. Agarwal
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Patent number: 9743961Abstract: A fusion device includes a screw having a head and a shaft. A hollow bone dowel is disposed about the shaft of the screw. The bone dowel is formed from a bone-like, biocompatible, or allograft material.Type: GrantFiled: June 24, 2014Date of Patent: August 29, 2017Assignee: The University of ToledoInventors: Vijay K. Goel, Anand K. Agarwal, David Dick
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Publication number: 20170196702Abstract: A metering delivery apparatus for injecting bone graft cement includes a body portion, a material containment vessel, an actuator, and a control unit. The body portion includes a drive housing that supports an actuator drivetrain and receiver end that supports the material containment vessel. The actuator has a first end connected to the actuator drivetrain and a second end that supports a moveable portion of the vessel to dispense material in the vessel and a retracting movement that relieves pressure applied to the material. The control unit receives actuator parameter inputs and includes a sensor to detect a signal of at least one of a pressure level and a time period. The sensor provides the detected signal to the control unit such that the control unit operates the actuator between the dispensing and retracting movements based on the detected signal and the actuator parameter inputs.Type: ApplicationFiled: June 24, 2015Publication date: July 13, 2017Applicant: The University of ToledoInventors: Anand K. Agarwal, Vijay K. Goel, Joel M. Gerber, Aakash Agarwal
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Publication number: 20160279280Abstract: Macroporous cement compositions, methods of making the same, and methods of using the same, are described.Type: ApplicationFiled: November 21, 2014Publication date: September 29, 2016Applicant: The University of ToledoInventors: Sarit B. BHADURI, Huan ZHOU, Anand K. AGARWAL, Vijay K. GOEL, Sameh SALEH