Patents by Inventor Anand Minajigi

Anand Minajigi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for reactivating genes on the inactive X chromosome
    Patent number: 11912994
    Abstract: Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5?-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: February 27, 2024
    Assignee: The General Hospital Corporation
    Inventors: Jeannie T. Lee, Anand Minajigi, Lieselot Carrette
  • METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME
    Publication number: 20230020545
    Abstract: Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5?-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein.
    Type: Application
    Filed: March 26, 2021
    Publication date: January 19, 2023
    Inventors: Jeannie T. Lee, Anand Minajigi, Lieselot Carrette
  • Methods for reactivating genes on the inactive X chromosome
    Patent number: 10961532
    Abstract: Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: March 30, 2021
    Assignee: The General Hospital Corporation
    Inventors: Jeannie T. Lee, Anand Minajigi, Lieselot Carrette
  • METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME
    Publication number: 20190048339
    Abstract: Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein.
    Type: Application
    Filed: April 6, 2016
    Publication date: February 14, 2019
    Inventors: Jeannie T. Lee, Anand Minajigi, Lieselot Carrette