Patents by Inventor Anand Prakash Khedkar

Anand Prakash Khedkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the purification of macrolides
    Patent number: 7473366
    Abstract: The invention relates to a process for the recovery of a macrolide in substantial pure form including: a) treating an impure or crude macrolide with water immiscible solvent to form a mixture, b) optionally concentrating the mixture, c) treating with ammonia gas to phase out impurities, d) separating impurities, e) optionally concentrating a phase containing the macrolide, f) loading on silica gel chromatography, optionally reversed phase or pretreated with silver, and eluting the macrolide, g) affording the macrolide in the substantially pure form, h) optional repetition of steps f and g to afford the macrolide in the substantially pure form. The macrolide is preferably tacrolimus, immunomycin or sirolimus.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: January 6, 2009
    Assignee: BioCon Limited
    Inventors: Nitin Sopanrao Patil, Rakesh Mendhe, Anand Prakash Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja
  • Manufacture and purification of cyclosporin A
    Patent number: 7176001
    Abstract: The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and subsequent chromatographic procedures to get pharmaceutical acceptable purity.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: February 13, 2007
    Assignee: Biocon Limited
    Inventors: Anand Prakash Khedkar, Pampapathy Subramaniyam, Konayakanahalli Nanjunda Swamy Anand, Melarkode Ramkrishna, Shreehas Pradeep Tambe, Sambasivam Ganesh, Anindya Sircar, Shrikumar Suryanarayan
  • Manufacture and purification of mycophenolic acid
    Patent number: 6927047
    Abstract: The present invention provides an improved method for the manufacture of Mycophenolic acid by solid substrate fermentation of Pencillium brevi-campactum, in a contained bioreactor under optimal fermentation parameters with its subsequent purification steps.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: August 9, 2005
    Assignee: Biocon Limited
    Inventors: Anindya Sircar, Shrikumar Suryanarayan, Anand Prakash Khedkar, Pampapathy Subramaniyam, Shreehas Pradeep Tambe