Abstract: Wiring is disclosed herein that is configured to supply IRE ablation signals through a catheter body and is resistant against dielectric breakdown, arcing, and noise during ablation. The wiring includes a highly conductive core, a conductive cover surrounding the core that has lower electrical and/or thermal conductivity than the core, and an insulative jacket surrounding the conductive cover. A catheter including such wiring may be suitable for supplying electrical signals to tissue to perform IRE ablation. In some examples, such a catheter can also be suitable for reversible electroporation and/or RF ablation.

Abstract: A system, which includes a first device associated with a user, a second device configured to establish a user session and a server, performs storing a default user session setting associated with the user, the default user session setting defining a default user access privilege to functionality or content; determining that the first device is proximate to the second device; receiving a second user input requesting to modify the default user session setting, the second user input including modification data defining a restrictive modification to the default user session setting; modifying, at the server, the default user session setting based on the modification data to create a customized user session setting defining a customized user access privilege to the functionality or content available via the system; and establishing, at the second device, the customized user session for the user based on the customized user setting received from the server.

Abstract: The invention relates to a personal cleansing composition that delivers enhanced deposition of sunscreens on to the topical surface of the body. The composition more particularly provides for such wash off compositions that ensure that the sunscreens incorporated therein are stable and due to the high deposition on to surface provide high Sun Protection Factor (SPF). This is achieved through combination of two select water-soluble sunscreens in a high surfactant containing composition.

Abstract: Provided is a method and system for preventing transfer errors of big data, including dividing entire data to be transmitted by a first device into a plurality of pieces of entity data and allocating a resource to first entity data among the plurality of pieces of entity data, applying, by the first device, the first entity data to a filter to query for the first entity data, transmitting, by the first device, the first entity data to a second device based on a result of the query for the first entity data, and upon receiving a sync request for the first entity data from the second device, releasing, by the first device, the resource allocated to the first entity data.

Abstract: A medical probe includes a generally tubular member with a tip portion coupled to the tubular member. A puller wire is disposed in the tubular member and configured for movement along the longitudinal axis to bend the tip portion with respect to the longitudinal axis. An anchor is disposed within the tubular member and connected to the puller wire such that the anchor has a t-bar. The t-bar includes a generally transverse extension and a ferrule connected to the puller wire. The probe includes a fiber engaged to the generally transverse extension and extending distally into the probe to increase a strength of the anchor with respect to forces applied to the puller wire to deflect the tip of the medical probe.

Abstract: A center slide assembly for a multi-point exit device. Upper and lower spool assemblies may be displaced from first positions to second positions along an inner region of a center slide. The displacement of the spool assemblies may displace upper and lower pull cables so as to retract latch mechanisms from extended positions to retracted positions. A first latching pin may be displaced, along with the displacement of the upper spool assembly, along an abutment surface of a tilting link so as to pivotally displace the tilting link from an unlocked position to a locked position. Displacement of the lower spool assembly may displace a second latching pin to a position wherein the second latching pin may be received and retained within a jog of the tilting link when the tilting link is in the locked position, which may thereby retain the associated latch mechanism in the retracted position.

Abstract: A catheter can have a distal circular region that can contract in circumference via manipulation of a pull wire. The circular region can have electrodes distributed around the circumference that are suitable for mapping and/or ablation, and preferably suitable for IRE ablation. The catheter can include a cross-over region near a distal end of a shaft in which elongated elements extend at an angle to the longitudinal axis. The cross-over region can be bounded by an intermediate tube having four lumens and a distal tube having three lumens. The circular region can include structural features to facilitate contraction such as a support member having a preferable bending direction, polymer tubing segments positioned to inhibit bending stress on electrodes, navigation sensors positioned to inhibit bending stress on said sensors and electrodes, and a distal assembly at a distal end of the circular region.

Abstract: Examples presented herein generally include a catheter and a system configured to deliver electrical pulses for ablation by IRE and methods for constructing and using the same. The catheter and system can further be configured to delivery RF electrical current for thermal ablation interleaved with ablation by IRE, simultaneously with ablation by IRE, and/or separately from ablation by IRE. The catheter can have a linear distal portion with a tip electrode, a middle ring electrode, and a proximal ring electrode. The electrodes be configured in several combinations to provide unipolar ablation, bipolar ablation, and/or a combination thereof.

Abstract: A medical probe includes a generally tubular member with a tip portion coupled to the tubular member. A puller wire is disposed in the tubular member and configured for movement along the longitudinal axis to bend the tip portion with respect to the longitudinal axis. An anchor is disposed within the tubular member and connected to the puller wire such that the anchor has a t-bar. The t-bar includes a generally transverse extension and a ferrule connected to the puller wire. The t-bar has a polymeric member disposed on the generally transverse extension to increase a strength of the anchor with respect to forces applied to the puller wire to deflect the tip of the medical probe.

Abstract: Latch mechanisms adapted to prevent unauthorized displacement of a latch bolt from an extended, locked position to a retracted, unlocked position. The latch mechanisms prevent the failure of a latch bolt of one latch mechanism to return to an extended lock position from interfering with the ability of a latch bolt of an inter-related latch mechanism from being able to return to an extended, locked position. Further embodiments provide a mounting bracket mounted to a door to allow the associated latch mechanism to be indirectly secured to the door. Additionally, the mounting bracket may have a plurality of mounting orifices that allow the mounting bracket to be used with a wide range of latch mechanisms, as well as provide adjustable attachment of the latch mechanism to the mounting bracket.

Abstract: A thermocouple assembly may feature a plurality of temperature sensors formed by thermocouple junctions. The sensors may be disposed within an inner diameter of the tubular element and sealed within the tubular element by thermally conductive material. An air gap may be defined by the thermally conductive material and the interior diameter of the tubular element between each pair of adjacent temperature sensors to improve thermal isolation.

Abstract: A thermocouple assembly may feature a plurality of temperature sensors formed by thermocouple junctions. The sensors may be disposed upon a positioner, that has a configuration that displaces each of the plurality of temperature sensors from a longitudinal axis of the positioner.

Abstract: A latch mechanism having an adjustment mechanism that adjusts the distance to which a latch bolt extends into a mating recess. The adjustment mechanism may include a driver component and a driven component. Rotation of the driver component about a first axis may displace the driven component, thereby causing the position of the latch bolt to be adjusted along a second axis that is non-parallel to the first axis. According to certain embodiments, the first axis is perpendicular to the second axis. The latch mechanism may also include an inner housing that is displaced as the latch bolt is extended into, and retracted from, a mating recess in an adjacent structure. Further, the position of the inner housing may remain generally static as the position of the latch bolt is adjusted along the second axis via operation of the adjustment mechanism.

Abstract: A catheter is described with an end effector having densely arrayed electrodes on three loops which are arrayed in various planar configurations when the end effector is unconstrained. The end effector has first, second and third loop members, each loop member includes two spines and a connector that connects the two spines to define a loop extending away from a tubular member of the catheter such that the first, second and third loop members are configured so that each connector of each of the first, second and third loop members is in contact with only one connector of the adjacent loop member.

Abstract: A thermocouple assembly may feature a plurality of temperature sensors formed by thermocouple junctions. The sensors may be disposed upon a substrate, that has a curvature that biases each of the plurality of temperature sensors in a desired direction.

Abstract: Described and illustrated is a medical probe that includes a generally tubular member with a tip portion coupled to the tubular member. A puller wire is disposed in the tubular member and configured for movement along the longitudinal axis to bend the tip portion with respect to the longitudinal axis. An anchor is disposed within the tubular member and connected to the puller wire such that the anchor has a t-bar. The t-bar includes a generally transverse extension and a ferrule connected to the puller wire. The t-bar has a polymeric member disposed on the generally transverse extension to increase a strength of the anchor with respect to forces applied to the puller wire to deflect the tip of the medical probe.

Abstract: Latch mechanisms adapted to prevent unauthorized displacement of a latch bolt from an extended, locked position to a retracted, unlocked position. The latch mechanisms prevent the failure of a latch bolt of one latch mechanism to return to an extended lock position from interfering with the ability of a latch bolt of an inter-related latch mechanism from being able to return to an extended, locked position. Further embodiments provide a mounting bracket mounted to a door to allow the associated latch mechanism to be indirectly secured to the door. Additionally, the mounting bracket may have a plurality of mounting orifices that allow the mounting bracket to be used with a wide range of latch mechanisms, as well as provide adjustable attachment of the latch mechanism to the mounting bracket.

Abstract: A catheter tip may be a fabricated as a planar flexible circuit, e.g., via lithography, as having a first planar segment and a second planar segment that includes various electrodes on different sectors that are insulated from each other. The tip may be deformed to have a non-planar configuration, e.g., cylindrical, and then assembled onto a catheter. The catheter may be used to monitor ECG signals and temperature and to precisely deliver ablative energy to tissues via the various electrodes. ECG signals and temperature may be monitored for one sector while ablation energy is being delivered to another sector.

Abstract: A center slide assembly for a multi-point exit device. Upper and lower spool assemblies may be displaced from first positions to second positions along an inner region of a center slide. The displacement of the spool assemblies may displace upper and lower pull cables so as to retract latch mechanisms from extended positions to retracted positions. A first latching pin may be displaced, along with the displacement of the upper spool assembly, along an abutment surface of a tilting link so as to pivotally displace the tilting link from an unlocked position to a locked position. Displacement of the lower spool assembly may displace a second latching pm to a position wherein the second latching pin may be received and retained within a jog of the tilting link when the tilting link is in the locked position, which may thereby retain the associated latch mechanism in the retracted position.

Abstract: Latch mechanisms adapted to prevent unauthorized displacement of a latch bolt from an extended, locked position to a retracted, unlocked position. The latch mechanisms prevent the failure of a latch bolt of one latch mechanism to return to an extended lock position from interfering with the ability of a latch bolt of an inter-related latch mechanism from being able to return to an extended, locked position. Further embodiments provide a mounting bracket mounted to a door to allow the associated latch mechanism to be indirectly secured to the door. Additionally, the mounting bracket may have a plurality of mounting orifices that allow the mounting bracket to be used with a wide range of latch mechanisms, as well as provide adjustable attachment of the latch mechanism to the mounting bracket.