Patents by Inventor Anand Swaroop

Anand Swaroop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11421219
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: August 23, 2022
    Assignee: THE USA, AS REPRESENTED BY THE SECRETARY, DHHS
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • Publication number: 20210106646
    Abstract: Disclosed are topical wound healing compositions useful in the holistic treatment of a patient's wound, particularly diabetic wounds of the foot. Methods of using these formulations topically and in coordinated use with certain oral supplements to improve treatment is also disclosed. In particular, formulations may include one or more of: water, Aloe Barbadensis leaf juice, micro silver, L-Arginine, locust bean gum, and Manuka honey. The topical formulations may be in the form of a gel.
    Type: Application
    Filed: October 10, 2019
    Publication date: April 15, 2021
    Applicant: Smart Products & Services Inc. (dba Aloevive)
    Inventors: Ramendra N. Pandey, Anand Swaroop, Usha Pandey, Ritu R. Pandey, Richa R. Rane, John D. Wilson
  • Publication number: 20200289670
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Application
    Filed: April 21, 2020
    Publication date: September 17, 2020
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suja Hiriyanna, Tiansen Li
  • Patent number: 10646588
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: May 12, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • Publication number: 20200024593
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Application
    Filed: May 28, 2019
    Publication date: January 23, 2020
    Inventors: Zhijian WU, Anand SWAROOP, Suddhasil MOOKHERJEE, Suja HIRIYANNA
  • Patent number: 10351844
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: July 16, 2019
    Assignee: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • Publication number: 20180043035
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Application
    Filed: March 11, 2016
    Publication date: February 15, 2018
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna, Tiansen Li
  • Publication number: 20170275615
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Application
    Filed: August 27, 2015
    Publication date: September 28, 2017
    Inventors: Zhijian WU, Anand SWAROOP, Suddhasil MOOKHERJEE, Suja HIRIYANNA
  • Publication number: 20130266937
    Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers (e.g., polymorphisms and/or haplotypes) for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
    Type: Application
    Filed: March 5, 2013
    Publication date: October 10, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Anand Swaroop, Goncalo Abecasis, Atsuhiro Kanda, Mingyao Li
  • Publication number: 20120135884
    Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
    Type: Application
    Filed: January 12, 2012
    Publication date: May 31, 2012
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Anand Swaroop, Goncalo Abecasis, Wei Chen, Dwight Stambolian, Albert O. Edwards
  • Patent number: 8119348
    Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: February 21, 2012
    Assignees: The Regents of the University of Michigan, The Trustees of the University of Pennsylvania, Mayo Foundation for Medical Education and Research
    Inventors: Anand Swaroop, Goncalo Abecasis, Wei Chen, Dwight Stambolian, Albert O. Edwards
  • Publication number: 20110014716
    Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
    Type: Application
    Filed: July 12, 2010
    Publication date: January 20, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Mayo Foundation for Medical Education and Research, The Trustees of the University of Pennsylvania
    Inventors: Anand Swaroop, Goncalo Abecasis, Wei Chen, Dwight Stambolian, Albert O. Edwards
  • Patent number: 7838231
    Abstract: The present invention relates to Nephronophthisis, in particular to the NPHP6 protein (nephrocystin-6) and nucleic acids encoding the NPHP6 protein. The present invention also provides assays for the detection of NPHP6, and assays for detecting NPHP6 polymorphisms and mutations associated with disease states.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: November 23, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: Friedhelm Hidebrandt, Edgar A. Otto, Hemant Khanna, Anand Swaroop
  • Patent number: 7741508
    Abstract: The invention provides a green process for direct oxidation of a large number of substituted or unsubstituted cinnamaldehydes or cinnamyl alcohols into the corresponding alkyl or aryl cinnamates in one step. The process of the present invention is a convenient and efficient green process for the preparation of various aryl or alkyl cinnamates under conventional, microwave and ultrasound directly from cinnamaldehydes or cinnamyl alcohols in the presence of an oxidizing agent, catalyst and an alcohol, with or without an organic solvent. These esters are immensely important compounds in flavor, perfumery and pharmaceutical industries. There are several prior arts available for the preparation of cinnamic esters, but all of them suffer from deficiencies such as use of expensive reagents and catalysts, harsh reaction conditions, use of toxic chemicals and others.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: June 22, 2010
    Assignee: Council of Scientific & Industrial Research
    Inventors: Arun Kumar Sinha, Anuj Sharma, Anand Swaroop, Vinod Kumar
  • Publication number: 20100136537
    Abstract: The present invention relates to photoreceptor cells. In particular, the present invention provides photoreceptor cells comprising heterologous nucleic acid sequences and transgenic animals comprising the same. The present invention also provides photoreceptor precursor cells (e.g., rod photoreceptor precursor cells), and methods of identifying, characterizing, isolating and utilizing the same. Compositions and methods of the present invention find use in, among other things, research, clinical, diagnostic, drug discovery, and therapeutic applications.
    Type: Application
    Filed: October 10, 2007
    Publication date: June 3, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Anand Swaroop, Masayuki Akimoto, Alan Mears, Hong Cheng, Edwin C.T. Oh
  • Publication number: 20090203001
    Abstract: The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers (e.g., polymorphisms and/or haplotypes) for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use in diagnostic, therapeutic, research, and drug screening applications.
    Type: Application
    Filed: August 25, 2008
    Publication date: August 13, 2009
    Applicant: The Regents of the University of Michigan
    Inventors: Anand Swaroop, Goncalo Abecasis, Mingyao Li, Atsuhiro Kanda
  • Patent number: 7517648
    Abstract: The present invention relates to Nephronophthisis, in particular to the NPHP5 protein (nephrocystin-5) and nucleic acids encoding the NPHP5 protein. The present invention also provides assays for the detection of NPHP5 polymorphisms and mutations associated with disease states.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: April 14, 2009
    Assignee: The Regents of the University of Michigan
    Inventors: Friedhelm Hildebrandt, Edgar A. Otto, Hemant Khanna, Anand Swaroop
  • Publication number: 20080045742
    Abstract: The invention provides a green process for direct oxidation of a large number of substituted or unsubstituted cinnamaldehydes or cinnamyl alcohols into the corresponding alkyl or aryl cinnamates in one step. The process of the present invention is a convenient and efficient green process for the preparation of various aryl or alkyl cinnamates under conventional, microwave and ultrasound directly from cinnamaldehydes or cinnamyl alcohols in the presence of an oxidizing agent, catalyst and an alcohol, with or without an organic solvent. These esters are immensely important compounds in flavor, perfumery and pharmaceutical industries. There are several prior arts available for the preparation of cinnamic esters, but all of them suffer from deficiencies such as use of expensive reagents and catalysts, harsh reaction conditions, use of toxic chemicals and others.
    Type: Application
    Filed: March 26, 2007
    Publication date: February 21, 2008
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Arun Sinha, Anuj Sharma, Anand Swaroop, Vinod Kumar
  • Publication number: 20080044831
    Abstract: The present invention relates to Nephronophthisis, in particular to the NPHP6 protein (nephrocystin-6) and nucleic acids encoding the NPHP6 protein. The present invention also provides assays for the detection of NPHP6, and assays for detecting NPHP6 polymorphisms and mutations associated with disease states.
    Type: Application
    Filed: April 5, 2007
    Publication date: February 21, 2008
    Applicant: The Regents of the University of Michigan
    Inventors: Friedhelm Hidebrandt, Edgar Otto, Hemant Khanna, Anand Swaroop
  • Publication number: 20050214864
    Abstract: The present invention relates to Nephronophthisis, in particular to the NPHP5 protein (nephrocystin-5) and nucleic acids encoding the NPHP5 protein. The present invention also provides assays for the detection of NPHP5 polymorphisms and mutations associated with disease states.
    Type: Application
    Filed: February 18, 2005
    Publication date: September 29, 2005
    Applicant: The Regents of the University of Michigan
    Inventors: Friedhelm Hildebrandt, Edgar Otto, Hemant Khanna, Anand Swaroop