Abstract: An apparatus for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells in a single cross section and a covering for at least partially covering the cells. A valve associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension of the covering, or may be separate from the covering, and may comprise flaps. A spiral covering may also form the valve.

Abstract: A fiber-reinforced device, such as an inflatable medical balloon, includes a cylindrical central portion. The balloon includes first and second tapered portions connected to the cylindrical central portion along a central longitudinal axis extending from a first end of the balloon to a second end of the balloon. In one embodiment, the balloon includes a single continuous fiber running substantially parallel to the longitudinal axis along the central portion, and having a plurality of turnaround points in each of the first and second tapered portions. The single continuous fiber does not extend along or around a reduced diameter portion, or neck, connected to each of the tapered portions, and thus may remain continuous even after the necks are trimmed away to connect the fiber-reinforced balloon to a catheter shaft.

Abstract: An apparatus for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells in a single cross section and a covering for at least partially covering the cells. A valve associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension of the covering, or may be separate from the covering, and may comprise flaps. A spiral covering may also form the valve.

Abstract: An apparatus for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells in a single cross section and a covering for at least partially covering the cells. A valve associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension of the covering, or may be separate from the covering, and may comprise flaps. A spiral covering may also form the valve.

Abstract: An apparatus for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells in a single cross section and a covering for at least partially covering the cells. A valve associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension of the covering, or may be separate from the covering, and may comprise flaps. A spiral covering may also form the valve.

Abstract: A surgical clip for illuminating tissue in a surgical field has first and second elongate arms and a connector joining the arms together. The arms are biased to expand laterally outward into an expanded configuration in which the arms engage the tissue in the surgical field with enough force to seat the clip without retracting the tissue. A waveguide illuminator is coupled to the first arm, and has a light input portion, a light output portion, and a light conducting portion extending between the light input portion and the light output portion. Light passes through the waveguide illuminator by total internal reflection, and the waveguide illuminator directs light to the tissue. Methods of using the illuminated clip are also disclosed.

Abstract: A surgical clip for illuminating tissue in a surgical field has first and second elongate arms and a connector joining the arms together. The arms are biased to expand laterally outward into an expanded configuration in which the arms engage the tissue in the surgical field with enough force to seat the clip without retracting the tissue. A waveguide illuminator is coupled to the first arm, and has a light input portion, a light output portion, and a light conducting portion extending between the light input portion and the light output portion. Light passes through the waveguide illuminator by total internal reflection, and the waveguide illuminator directs light to the tissue. Methods of using the illuminated clip are also disclosed.

Abstract: A surgical clip for illuminating tissue in a surgical field has first and second elongate arms and a connector joining the arms together. The arms are biased to expand laterally outward into an expanded configuration in which the arms engage the tissue in the surgical field with enough force to seat the clip without retracting the tissue. A waveguide illuminator is coupled to the first arm, and has a light input portion, a light output portion, and a light conducting portion extending between the light input portion and the light output portion. Light passes through the waveguide illuminator by total internal reflection, and the waveguide illuminator directs light to the tissue. Methods of using the illuminated clip are also disclosed.

Abstract: A surgical clip for illuminating tissue in a surgical field has first and second elongate arms and a connector joining the arms together. The arms are biased to expand laterally outward into an expanded configuration in which the arms engage the tissue in the surgical field with enough force to seat the clip without retracting the tissue. A waveguide illuminator is coupled to the first arm, and has a light input portion, a light output portion, and a light conducting portion extending between the light input portion and the light output portion. Light passes through the waveguide illuminator by total internal reflection, and the waveguide illuminator directs light to the tissue. Methods of using the illuminated clip are also disclosed.

Abstract: A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus updates a CIE in guaranteed non-MBSFN subframes. The apparatus refrains from updating at least one of an AGC, a TTL, an FTL, or an SNR estimation (FTL_SNR) in potential MBSFN subframes before a SIB is decoded to ascertain which subframes of a radio frame are MBSFN subframes and non-MBSFN subframes. The MBSFN subframes include a subset of the potential MBSFN subframes. The non-MBSFN subframes include a remaining subset of the potential MBSFN subframes and the guaranteed non-MBSFN subframes.

Abstract: Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.

Abstract: Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.

Abstract: Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.

Abstract: The present invention discloses novel stable oral pharmaceutical compositions comprising the active ingredient Clopidogrel bisulfate and hydrophilic polymers along with pharmaceutically acceptable excipients. Particularly, the said Clopidogrel bisulfate is crystalline Form 1 and the composition additionally comprises of one or more chelating agents and antioxidants. Further the invention relates to a novel process for preparation of stable pharmaceutical compositions wherein the Clopidogrel bisulfate Form I is coated with a hydrophilic polymer thereby providing an increased physical and chemical stability to the composition.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises a deformable element to control the opening of an air passageway. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises a deformable element to control the opening of an air passageway. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein. In one embodiment, the airway implant device includes a self-charging element. The self-charging element is typically an electroactive polymer which generates energy during its movement and this energy is used to activate the deformable element of the airway implant device.

Abstract: Several electroactive polymer (EAP) actuated vascular assist devices are provided that can be readily implanted within the body of a patient without coming in direct blood contact. The devices are also readily repositioned and/or removed from contact with the internal vasculature or may even be turned OFF remotely. In addition, there is provided a method of fabrication and a method of implanting such devices. There are also provided methods for the augmentation of a body lumen through the use of hemodynamic signals such as pressure or ECG signals to synchronize EAP actuation in the vascular assist system.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises an actuator element to control the opening of an air passageway. Preferably the actuator element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls in order to prevent the collapse of an air passageway. Some embodiments of the invention include a sensor capable of sensing the possible occurrence of an apneic event and activating the actuator element of the airway implant device. Some embodiments include a housing designed to conform to the shape of the palate. Some embodiments include an attachment element to secure the device to tissue. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.

Abstract: An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device comprises a deformable element to control the opening of an air passageway. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Some embodiments of the invention include a sensor capable of sensing the possible occurrence of an apneic event and activating the deformable element of the airway implant device. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.