Patents by Inventor Ananth J. Madhuranthakam
Ananth J. Madhuranthakam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11852706Abstract: The present invention includes a method and apparatus for improved magnetic resonance imaging with simultaneous fat and fluid suppression of a subject comprising: acquiring four images, in-phase (IP) and out-of-phase (OP) at a short and a long echo time (TE) using a single-shot turbo spin echo from one or more magnetic resonance imager excitations: processing at least a pair of IP and OP images at a short and a long TE using single-shot turbo spin echo using a Dixon reconstruction; processing the pair of IP and OP images; subtracting the long TE water-only image from the shared-field-map Dixon reconstruction from the short TE water-only image to provide a fluid attenuation; processing water-only and fat-only images at the short and long TE to generate quantitative fat-fraction map; and reconstructing one or more 3D magnetic resonance images.Type: GrantFiled: February 8, 2019Date of Patent: December 26, 2023Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Ananth J. Madhuranthakam, Robert E. Lenkinski, Xinzeng Wang, Ivan Pedrosa
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Patent number: 11169237Abstract: The present invention includes a computerized method of detecting fluid flow in a vessel, the method comprising: obtaining at least one non-contrast enhanced magnetic resonance image from a magnetic resonance imager; performing a phase sensitive reconstruction of the at least one non-contrast enhanced magnetic resonance image using a processor; combining the phase sensitive reconstruction with a velocity selective preparation of the non-contrast enhanced magnetic resonance image, to determine using the processor, in a single acquisition, at least one of: a flow direction of a fluid in the vessel, a reduction or elimination of a background signal, body fat, water/fat separation, or differentiation of a fast moving flow signal from a slow moving flow signal in an opposite direction with suppression of the background signal; and storing or displaying at least one of flow direction or flow strength of the fluid flow in the vessel obtained from the single acquisition.Type: GrantFiled: October 5, 2016Date of Patent: November 9, 2021Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Ananth J. Madhuranthakam, Xinzeng Wang
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Publication number: 20210055364Abstract: The present invention includes a method and apparatus for improved magnetic resonance imaging with simultaneous fat and fluid suppression of a subject comprising: acquiring four images, in-phase (IP) and out-of-phase (OP) at a short and a long echo time (TE) using a single-shot turbo spin echo from one or more magnetic resonance imager excitations: processing at least a pair of IP and OP images at a short and a long TE using single-shot turbo spin echo using a Dixon reconstruction; processing the pair of IP and OP images; subtracting the long TE water-only image from the shared-field-map Dixon reconstruction from the short TE water-only image to provide a fluid attenuation; processing water-only and fat-only images at the short and long TE to generate quantitative fat-fraction map; and reconstructing one or more 3D magnetic resonance images.Type: ApplicationFiled: February 8, 2019Publication date: February 25, 2021Inventors: Ananth J. Madhuranthakam, Robert E. Lenkinski, Xinzeng Wang, Ivan Pedrosa
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Publication number: 20180284209Abstract: The present invention includes a computerized method of detecting fluid flow in a vessel, the method comprising: obtaining at least one non-contrast enhanced magnetic resonance image from a magnetic resonance imager; performing a phase sensitive reconstruction of the at least one non-contrast enhanced magnetic resonance image using a processor; combining the phase sensitive reconstruction with a velocity selective preparation of the non-contrast enhanced magnetic resonance image, to determine using the processor, in a single acquisition, at least one of: a flow direction of a fluid in the vessel, a reduction or elimination of a background signal, body fat, water/fat separation, or differentiation of a fast moving flow signal from a slow moving flow signal in an opposite direction with suppression of the background signal; and storing or displaying at least one of flow direction or flow strength of the fluid flow in the vessel obtained from the single acquisition.Type: ApplicationFiled: October 5, 2016Publication date: October 4, 2018Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Ananth J. Madhuranthakam, Xinzeng Wang
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Patent number: 9063206Abstract: A system and method for double inversion recovery for reduction of T1 contribution to fluid-attenuated inversion recovery imaging include a computer programmed to prepare a double inversion recovery (DIR) sequence comprising a pair of inversion pulses and an excitation pulse, execute the DIR sequence to acquire MR data from an imaging subject, and reconstruct an image based on the acquired MR data. The preparation of the DIR sequence comprises optimizing a first inversion time (TI1) between the pair of inversion pulses and a second inversion time (TI2) between one of the pair of inversion pulses and the excitation pulse to cause a first tissue of the imaging subject to be suppressed in the image and to reduce a T1 contrast between a second tissue and a third tissue of the imaging subject in the image.Type: GrantFiled: March 22, 2012Date of Patent: June 23, 2015Assignees: General Electric Company, Beth Israel Deaconess Medical CenterInventors: Ananth J. Madhuranthakam, David C. Alsop
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Patent number: 8704518Abstract: An MRI apparatus is disclosed, the MRI apparatus comprising a computer programmed to apply a fluid suppression technique prior to an imaging pulse-gradient sequence, wherein the fluid suppression technique is configured to suppress signals from fluids having long longitudinal relaxation times, and apply a fat suppression technique after the fluid suppression technique and prior to the imaging pulse-gradient sequence, wherein the fat suppression technique is configured to suppress fat signals. The computer is further programmed to apply a flow suppression preparation sequence after the fat suppression technique and prior to the imaging pulse-gradient sequence, wherein the flow suppression preparation sequence is configured to suppress moving tissue signals. The computer is also programmed to apply the imaging pulse-gradient sequence, cause the RF transceiver system to acquire MR signals during the imaging pulse-gradient sequence, and reconstruct an image from the acquired MR signals.Type: GrantFiled: April 15, 2011Date of Patent: April 22, 2014Assignees: General Electric Company, Beth Israel Deaconess Medical CenterInventors: David C. Alsop, Neil M. Rofsky, Ananth J. Madhuranthakam
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Patent number: 8587305Abstract: An apparatus and method for separating the NMR signal contributions from a plurality of different species having different chemical shifts is disclosed. The apparatus acquires MR image data sets including a first species signal and a second species signal, generates a first species image from the acquired MR image data, and generates a second species image from the acquired MR image data. The apparatus also identifies voxels in the second species image representative of only the second species and, for voxels identified as being representative of only the second species, calculates a fraction of the second species signal appearing in the first species image. The apparatus generates a modified first species image based on the fraction of the second species signal appearing in the first species image, with the modified first species image having a different fraction of the second species as compared to the first species image.Type: GrantFiled: January 11, 2011Date of Patent: November 19, 2013Assignees: General Electric Company, Beth Israel Deaconess Medical CenterInventors: Ananth J. Madhuranthakam, Huanzhou Yu, David C. Alsop
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Patent number: 8320646Abstract: An MRI system produces a three-dimensional image by acquiring NMR signals that fully sample a central region of k-space and partially sample peripheral k-space as a set of asymmetric radial sectors. The NMR signals are acquired with a plurality of receive channels and coils. An image is reconstructed using a homodyne reconstruction combined with SENSE processing.Type: GrantFiled: May 2, 2006Date of Patent: November 27, 2012Assignee: MAYO Foundation for Medical Education and ResearchInventors: Houchun H. Hu, Ananth J. Madhuranthakam, Stephen J. Riederer
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Publication number: 20120262169Abstract: A system and method for double inversion recovery for reduction of T1 contribution to fluid-attenuated inversion recovery imaging include a computer programmed to prepare a double inversion recovery (DIR) sequence comprising a pair of inversion pulses and an excitation pulse, execute the DIR sequence to acquire MR data from an imaging subject, and reconstruct an image based on the acquired MR data. The preparation of the DIR sequence comprises optimizing a first inversion time (TI1) between the pair of inversion pulses and a second inversion time (TI2) between one of the pair of inversion pulses and the excitation pulse to cause a first tissue of the imaging subject to be suppressed in the image and to reduce a T1 contrast between a second tissue and a third tissue of the imaging subject in the image.Type: ApplicationFiled: March 22, 2012Publication date: October 18, 2012Inventors: Ananth J. Madhuranthakam, David C. Alsop
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Publication number: 20120262175Abstract: An MRI apparatus is disclosed, the MRI apparatus comprising a computer programmed to apply a fluid suppression technique prior to an imaging pulse-gradient sequence, wherein the fluid suppression technique is configured to suppress signals from fluids having long longitudinal relaxation times, and apply a fat suppression technique after the fluid suppression technique and prior to the imaging pulse-gradient sequence, wherein the fat suppression technique is configured to suppress fat signals. The computer is further programmed to apply a flow suppression preparation sequence after the fat suppression technique and prior to the imaging pulse-gradient sequence, wherein the flow suppression preparation sequence is configured to suppress moving tissue signals. The computer is also programmed to apply the imaging pulse-gradient sequence, cause the RF transceiver system to acquire MR signals during the imaging pulse-gradient sequence, and reconstruct an image from the acquired MR signals.Type: ApplicationFiled: April 15, 2011Publication date: October 18, 2012Inventors: David C. Alsop, Neil M. Rofsky, Ananth J. Madhuranthakam
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Publication number: 20120176131Abstract: An apparatus and method for separating the NMR signal contributions from a plurality of different species having different chemical shifts is disclosed. The apparatus acquires MR image data sets including a first species signal and a second species signal, generates a first species image from the acquired MR image data, and generates a second species image from the acquired MR image data. The apparatus also identifies voxels in the second species image representative of only the second species and, for voxels identified as being representative of only the second species, calculates a fraction of the second species signal appearing in the first species image. The apparatus generates a modified first species image based on the fraction of the second species signal appearing in the first species image, with the modified first species image having a different fraction of the second species as compared to the first species image.Type: ApplicationFiled: January 11, 2011Publication date: July 12, 2012Inventors: Ananth J. Madhuranthakam, Huanzhou Yu, David C. Alsop
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Patent number: 7610076Abstract: MRA data is acquired from an extended field of view by translating the patient through the bore of the MRI system as three-dimensional MRA data sets are acquired and time-resolved images reconstructed. The leading edge of a contrast bolus can be tracked in these images and parameters such as bolus velocity and bolus arrival time can be calculated to provide functional information in addition to anatomical information. Temporal resolution is improved by undersampling peripheral k-space and sampling the center of k-space at a higher temporal rate.Type: GrantFiled: March 5, 2004Date of Patent: October 27, 2009Assignee: Mayo Foundation for Medical Education and ResearchInventors: Stephen J. Riederer, David G. Kruger, Ananth J. Madhuranthakam
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Publication number: 20080187196Abstract: An MRI system produces a three-dimensional image by acquiring NMR signals that fully sample a central region of k-space and partially sample peripheral k-space as a set of asymmetric radial sectors. The NMR signals are acquired with a plurality of receive channels and coils. An image is reconstructed using a homodyne reconstruction combined with SENSE processing.Type: ApplicationFiled: May 2, 2006Publication date: August 7, 2008Inventors: Houchun H. Hu, Ananth J. Madhuranthakam, Stephen J. Riederer
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Publication number: 20040210129Abstract: MRA data is acquired from an extended field of view by translating the patient through the bore of the MRI system as three-dimensional MRA data sets are acquired and time-resolved images reconstructed. The leading edge of a contrast bolus can be tracked in these images and parameters such as bolus velocity and bolus arrival time can be calculated to provide functional information in addition to anatomical information. Temporal resolution is improved by undersampling peripheral k-space and sampling the center of k-space at a higher temporal rate.Type: ApplicationFiled: March 5, 2004Publication date: October 21, 2004Inventors: Stephen J. Riederer, David G. Kruger, Ananth J. Madhuranthakam