Patents by Inventor Anantha Rajmohan MUTHUSAMY

Anantha Rajmohan MUTHUSAMY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID STATE FORMS OF TRILACICLIB AND OF TRILACICLIB SALTS
    Publication number: 20230374028
    Abstract: The present disclosure encompasses solid state forms of Trilaciclib and of Trilaciclib salts, in embodiments crystalline polymorphs of Trilaciclib and of Trilaciclib salts, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 8, 2021
    Publication date: November 23, 2023
    Applicant: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Meenakshi Sundaram Somasundaram, Yogesh Dhananjay Wagh, Parven Kumar Luthra
  • Process for the preparation of Remimazolam and solid state forms of Remimazolam salts
    Patent number: 11820776
    Abstract: The present disclosure relates to novel processes for the preparation of short acting benzodiazepines as well as to novel intermediates in this process. More particularly the disclosure relates to processes and intermediates for preparation of Methyl 3-[(4S)-8-bromo-1-methyl-6-(pyridin-2-yl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate, commonly known as Remimazolam. The present disclosure also relates to solid state forms of Remimazolam salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: November 21, 2023
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Dolitzky Ben-Zion, Mendelovici Marioara, Bodkhe Arjun Rajaram, Mane Ganesh Shivaji, Samala Rajamouli Srihari, Joshi Ashutosh Vijay, Parven Kumar Luthra, Amit Singh, Anantha Rajmohan Muthusamy
  • SOLID STATE FORMS OF AT-001 AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20230322786
    Abstract: The present disclosure encompasses solid state forms of AT-001, in embodiments crystalline polymorphs of AT-001 or salts or co-crystals of AT-001, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 7, 2021
    Publication date: October 12, 2023
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Yogesh Dhananjay Wagh
  • SOLID STATE FORMS OF AVAPRITINIB SALTS
    Publication number: 20230279009
    Abstract: The present disclosure encompasses solid state forms of Avapritinib salts and co-crystals of the hydrochloride salt of Avapritinib, processes for preparation thereof, and pharmaceutical compositions thereof as well as their pharmaceutical use, in particular in the treatment of gastrointestinal stromal tumors (GIST), solid tumors and Advanced Systemic Mastocytosis.
    Type: Application
    Filed: June 15, 2021
    Publication date: September 7, 2023
    Inventors: Anantha Rajmohan Muthusamy, Yogesh Dhananjay Wagh, Siva Rama Krishna Muppalla, Parven Kumar Luthra, Meenakshi Sundaram Somasundaram
  • Solid state forms of ivosidenib
    Patent number: 11673880
    Abstract: Solid state forms of Ivosidenib, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof are disclosed.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: June 13, 2023
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Venkata Subbarao Yazali, Parven Kumar Luthra, Sanjay Lakhabhai Vasoya, Bhatu Tumba Patil, Amit Kumar Taneja, Naveen Chandra Srivastav, Rinku Singh, Vadivelan Rengasamy, Abhilash Tyagi
  • SOLID STATE FORMS OF AVAPRITINIB AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20230103724
    Abstract: The present disclosure encompasses solid state forms of Avapritinib, in embodiment crystalline polymorphs of Avapritinib, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: March 11, 2021
    Publication date: April 6, 2023
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Sundara Lakshmi Kanniah, Vaibhav Suresh Daund, Parven Kumar Luthra, Yogesh Dhananjay Wagh, Meenakshi Sundaram Somasundaram
  • PROCESSES FOR THE PREPARATION OF GLASDEGIB AND SALT THEREOF AND SOLID STATE FORMS OF GLASDEGIB MALEATE AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20230107634
    Abstract: The present disclosure relates to safe and efficient processes for the synthesis of Glasdegib or salts thereof, preferably Glasdegib Maleate. The present disclosure also encompasses solid state forms of Glasdegib maleate, in embodiments crystalline polymorphs of Glasdegib maleate, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 28, 2021
    Publication date: April 6, 2023
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Rajendra Popat Chemate, Bhatu Tumba Patil, Elluru Subbi Reddy, Parven Kumar Luthra, Sanjay Lakhabhai Vasoya, Dnyaneshwar Kondibhau Nighot
  • SOLID STATE FORMS OF AVASOPASEM MANGANESE AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20230071463
    Abstract: The present disclosure encompasses solid state forms of Avasopasem manganese, in embodiments crystalline polymorphs of Avasopasem manganese, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 12, 2021
    Publication date: March 9, 2023
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Yogesh Dhananjay Wagh
  • SOLID STATE FORMS OF LUCERASTAT AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20220411371
    Abstract: The present disclosure encompasses solid state forms of Lucerastat, in embodiments crystalline Lucerastat: L-Pyroglutamic acid, crystalline Lucerastat: Salicylic acid, crystalline Lucerastat: Fumaric acid, crystalline Lucerastat: Benzoic acid and crystalline Lucerastat: o-Acetylsalicylic acid, solid state form thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 23, 2020
    Publication date: December 29, 2022
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Yogesh Dhananjay Wagh
  • SOLID STATE FORMS OF FEZAGEPRAS AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20220380288
    Abstract: The present disclosure encompasses solid state forms of Setogepram, in embodiments crystalline polymorphs or salts of Setogepram, particularly Setogepram sodium, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 27, 2020
    Publication date: December 1, 2022
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Venkata Subbarao Yazali
  • NEW CRYSTALLINE POLYMORPHS OF RIVOCERANIB AND RIVOCERANIB MESYLATE
    Publication number: 20220371998
    Abstract: The present disclosure encompasses crystalline polymorphs of Rivoceranib and Rivoceranib mesylate (Apatinib mesylate), processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: July 27, 2022
    Publication date: November 24, 2022
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Elluru Subbireddy
  • Crystalline polymorphs of Rivoceranib and Rivoceranib mesylate
    Patent number: 11434202
    Abstract: The present disclosure encompasses crystalline polymorphs of Rivoceranib and Rivoceranib mesylate (Apatinib mesylate), processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: September 6, 2022
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Elluru Subbireddy
  • SOLID STATE FORMS OF BALOXAVIR MARBOXIL
    Publication number: 20220153753
    Abstract: The present disclosure relates to solid state forms of baloxavir marboxil, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 5, 2020
    Publication date: May 19, 2022
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Amol Gulab Khatik, Sundara Lakshmi Kanniah, Yogesh Dhananjay Wagh, Parven Kumar Luthra, Brijnath P. Chaurasia, Ram Karan Prajapati
  • SOLID STATE FORMS OF ACALABRUTINIB
    Publication number: 20220153744
    Abstract: The present disclosure relates to solid state forms of Acalabrutinib, processes for the preparation thereof and pharmaceutical compositions comprising said solid state forms of Acalabrutinib.
    Type: Application
    Filed: March 26, 2020
    Publication date: May 19, 2022
    Inventors: Sundara Lakshmi Kanniah, Anantha Rajmohan Muthusamy, Bhupendra Prakash Tyagi, Vrajlal Karamshibhai Gothalia, Sanjay Jaiswal, Sadanand Hardeo Maurya, Parven Kumar Luthra, Amit Gupta, Manigandan Gopal, Shilpi Pandey
  • SOLID STATE FORMS OF REPROXALAP
    Publication number: 20220009893
    Abstract: The present disclosure relates to solid state forms of Reproxalap salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 12, 2019
    Publication date: January 13, 2022
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Rahul Kumar Reddy Putikum, Sudhanshu Saxena, Amol Bandal
  • Crystalline polymorph of Ponesimod
    Patent number: 11220488
    Abstract: The present disclosure encompasses crystalline polymorphs of Ponesimod, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: January 11, 2022
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Sundara Lakshmi Kanniah, Kanhaiyalal, Anantha Rajmohan Muthusamy
  • Solid state forms of apalutamide
    Patent number: 11149017
    Abstract: Disclosed are solid state forms of Apalutamide and salts thereof, processes for preparation thereof and pharmaceutical compositions thereof.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: October 19, 2021
    Assignee: WATSON LABORATORIES INC.
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Nitin Dnyaneshwar Arote, Omkar Vilas Bhagwat, Jitendra Kamalakar Sonar, Vitthal Baburao Poundkar, Yogesh Dhananjay Wagh
  • SOLID STATE FORMS OF IVOSIDENIB
    Publication number: 20210309639
    Abstract: Solid state forms of Ivosidenib, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof are disclosed.
    Type: Application
    Filed: June 18, 2021
    Publication date: October 7, 2021
    Inventors: Anantha Rajmohan Muthusamy, Amit Singh, Venkata Subbarao Yazali, Parven Kumar Luthra, Sanjay Lakhabhai Vasoya, Bhatu Tumba Patil, Amit Kumar Taneja, Naveen Chandra Srivastav, Rinku Singh, Vadivelan Rengasamy, Abhilash Tyagi
  • PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS
    Publication number: 20210277013
    Abstract: The present disclosure relates to novel processes for the preparation of short acting benzodiazepines as well as to novel intermediates in this process. More particularly the disclosure relates to processes and intermediates for preparation of Methyl 3-[(4S)-8-bromo-1-methyl-6-(pyridin-2-yl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate, commonly known as Remimazolam. The present disclosure also relates to solid state forms of Remimazolam salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 9, 2021
    Inventors: Dolitzky Ben-Zion, Mendelovici Marioara, Bodkhe Arjun Rajaram, Mane Ganesh Shivaji, Samala Rajamouli Srihari, Joshi Ashutosh Vijay, Parven Kumar Luthra, Amit Singh, Anantha Rajmohan Muthusamy
  • NEW CRYSTALLINE POLYMORPHS OF RIVOCERANIB AND RIVOCERANIB MESYLATE
    Publication number: 20210253529
    Abstract: The present disclosure encompasses crystalline polymorphs of Rivoceranib and Rivoceranib mesylate (Apatinib mesylate), processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 4, 2019
    Publication date: August 19, 2021
    Inventors: Anantha Rajmohan Muthusamy, Sundara Lakshmi Kanniah, Elluru Subbireddy