Patents by Inventor Anantha Shekhar

Anantha Shekhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective ligands for modulation of GIRK channels
    Patent number: 11952370
    Abstract: Selective small molecule regulators of GIRK potassium channels are provided, which are effective in treatment of post-traumatic stress disorder and other medical conditions.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: April 9, 2024
    Assignees: Northeastern University, Indiana University Research and Technology Corporation
    Inventors: Ganeshsingh A. Thakur, Diomedes E. Logothetis, Lucas Cantwell, Yu Xu, Anantha Shekhar
  • METHODS AND COMPOSITIONS FOR PANIC DISORDERS
    Publication number: 20160326528
    Abstract: Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
    Type: Application
    Filed: June 30, 2016
    Publication date: November 10, 2016
    Inventors: Anantha Shekhar, Philip L. Johnson
  • Methods and compositions for panic disorders
    Patent number: 9441226
    Abstract: Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: September 13, 2016
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Anantha Shekhar, Philip L. Johnson
  • COMPOSITIONS AND METHODS FOR TREATING PTSD AND RELATED DISEASES
    Publication number: 20150105324
    Abstract: The invention described herein pertains to compositions and methods for treating PTSD and related diseases. In particular, the invention described herein pertains to compositions and methods for treating PTSD and related diseases by administering modulators of NMDA NR2-PSD95-nNOS signaling.
    Type: Application
    Filed: April 26, 2013
    Publication date: April 16, 2015
    Inventors: Anantha Shekhar, Yvonne Lai
  • Treatment of glaucoma
    Patent number: 8980910
    Abstract: A method is provided for treating patients suffering from elevated intraocular pressure or fluctuation in intraocular pressure, including for example glaucoma patients. The method comprises administering to the patient an inhibitor of orexin activity in an amount sufficient to reduce intraocular pressure or intraocular pressure fluctuation in one or both eyes of the patient.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: March 17, 2015
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Brian C. Samuels, Anantha Shekhar, Philip L. Johnson
  • METHODS AND COMPOSITIONS FOR PANIC DISORDERS
    Publication number: 20150011613
    Abstract: Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
    Type: Application
    Filed: September 24, 2014
    Publication date: January 8, 2015
    Inventors: Anantha Shekhar, Philip L. Johnson
  • Methods for treating chronic obstructive pulmonary disease
    Patent number: 8877773
    Abstract: Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
    Type: Grant
    Filed: October 21, 2010
    Date of Patent: November 4, 2014
    Inventors: Anantha Shekhar, Philip L. Johnson
  • TREATMENTS FOR SOCIAL LEARNING DISORDERS
    Publication number: 20140107222
    Abstract: The use of Pak1 inhibitors to treat social or learning disabilities is disclosed. In one embodiment patients exhibiting social or learning disabilities as well as abnormally low NF1 activity are administered PAK inhibitors to treat the social or learning disabilities. Reductions in PAK activity have been found to ameliorate the effects of aberrant neurofibromatosis type 1 activity.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Anantha SHEKHAR, D. Wade CLAPP
  • TREATMENT OF GLAUCOMA
    Publication number: 20140039003
    Abstract: A method is provided for treating patients suffering from elevated intraocular pressure or fluctuation in intraocular pressure, including for example glaucoma patients. The method comprises administering to the patient an inhibitor of orexin activity in an amount sufficient to reduce intraocular pressure or intraocular pressure fluctuation in one or both eyes of the patient.
    Type: Application
    Filed: March 29, 2012
    Publication date: February 6, 2014
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Brian C. Samuels, Anantha Shekhar, Philip L. Johnson
  • TREATMENT OF SYMPTOMS ASSOCIATED WITH MENOPAUSE
    Publication number: 20130191934
    Abstract: A method for treating symptoms associated with a dramatic reduction in reproductive hormone levels is provided, particularly in menopausal women and breast cancer survivors undergoing aromatase inhibitor therapy. The method comprises administered to a subject an inhibitor of orexin activity in an amount sufficient to reduce or decrease onset, progression, severity, frequency, duration or probability of one or more such symptoms. A method of detecting compounds having activity for relieving menopausal symptoms is also provided.
    Type: Application
    Filed: September 29, 2011
    Publication date: July 25, 2013
    Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORA
    Inventors: Anantha Shekhar, Philip L. Johnson
  • METHODS AND COMPOSITIONS FOR PANIC DISORDERS
    Publication number: 20120269810
    Abstract: Methods and compositions that down regulate the activity of orexins to treat panic disorder and panic-like responses associated with hypercapnic conditions are disclosed.
    Type: Application
    Filed: October 21, 2010
    Publication date: October 25, 2012
    Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
    Inventors: Anantha Shekhar, Philip L. Johnson