Patents by Inventor Anastasia Lomova

Anastasia Lomova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EDITING OF MONOGENIC DISORDERS IN HUMAN HEMATOPOIETIC STEM CELLS -- CORRECTION OF X-LINKED AGAMMAGLOBULINEMIA (XLA)
    Publication number: 20210379105
    Abstract: In certain embodiments methods of treating X-Linked agammaglobulinemia (XLA) in a mammal are provided where the methods comprise: i) providing differentiated T cells and/or stem/progenitor cells from the mammal; ii) performing a targeted insertion of a corrective BTK cDNA at the BTK gene locus in said cells to provide a corrected BTK gene in said cells; and iii) introducing said cells into said mammal where said corrected BTK gene is expressed in a physiologically regulated manner.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 9, 2021
    Applicant: The Regents of the University of California
    Inventors: Donald B. Kohn, Caroline Y. Kuo, David Gray, Zulema Romero Garcia, Roger P. Hollis, Anastasia Lomova