Patents by Inventor Anastasia ORME

Anastasia ORME has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260049342
    Abstract: The present invention relates to a biosynthetic route to precursors of the QS-7 molecule, as well as routes to make the QS-7 molecule, enzymes involved, the products produced and uses of the product.
    Type: Application
    Filed: December 23, 2022
    Publication date: February 19, 2026
    Inventors: Anne OSBOURN, James REED, Anastasia ORME, Laetitia MARTIN
  • Publication number: 20250369046
    Abstract: Aptamer detection techniques are described that may include aptamer modification to facilitate incorporation of adapter sequences. In an embodiment, a 3? end of an aptamer may be modified by deprotection and subsequent ligation to the deprotected 3? end or extension of the deprotected 3? end. The modifications at the 3? end of the adaptor may include adaptor sequences used for library preparation of a sequencing library.
    Type: Application
    Filed: March 8, 2024
    Publication date: December 4, 2025
    Inventors: Bryan Anstead, Carlo Randise-Hinchliff, Kuanlin Wu, Anthony Chau, Steven Norberg, Nithya Subramanian, Andrew Slatter, Yang Cao, Stephane Emond, Miguel Angel Aleman Garcia, Brian Tenner, Anastasia Orme
  • Publication number: 20250207166
    Abstract: The present invention relates to a biosynthetic route to the QS-21 and QS-18 molecules including the C-18 acyl chain and precursors thereof, as well as enzymes involved, the products produced and uses of the products.
    Type: Application
    Filed: December 23, 2022
    Publication date: June 26, 2025
    Inventors: Anne OSBOURN, James REED, Anastasia ORME, Laetitia MARTIN, Charlotte OWEN
  • Patent number: 12247209
    Abstract: The present invention relates generally to genes and polypeptides which have utility in glycosylating quillaic acid in host cells, including enzymes capable of successive glycosylation at the C-3 position of quillaic acid. The invention further relates to systems, methods and products employing the same.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: March 11, 2025
    Assignee: PLANT BIOSCIENCE LIMITED
    Inventors: Anne Osbourn, James Reed, Anastasia Orme, Thomas Louveau
  • Publication number: 20240102069
    Abstract: The present invention relates to a biosynthetic route to intermediates of the QS-21 molecule which are triterpenes from a saponin extract of the tree Quillaja saponaria comprising a quillaic acid backbone, as well as routes to make the QS-21 molecule, enzymes involved, the products produced and uses of the product.
    Type: Application
    Filed: December 22, 2021
    Publication date: March 28, 2024
    Inventors: Anne OSBOURN, James REED, Anastasia ORME
  • Publication number: 20230106588
    Abstract: The present invention relates generally to genes and polypeptides which have utility in glycosylating quillaic acid in host cells, including enzymes capable of successive glycosylation at the C-3 position of quillaic acid. The invention further relates to systems, methods and products employing the same.
    Type: Application
    Filed: June 25, 2020
    Publication date: April 6, 2023
    Inventors: Anne OSBOURN, James REED, Anastasia ORME, Thomas LOUVEAU