Patents by Inventor Anastasios DIMOU

Anastasios DIMOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EGFR EXPRESSION IS ASSOCIATED WITH DECREASED BENEFIT FROM TRASTUZUMAB IN THE NCCTG N9831 TRIAL
    Publication number: 20140170135
    Abstract: The subject invention provides a method for treating a patient having a tumor associated with HER2+ breast cancer comprising: measuring in a sample of the patient's tumor a level of expression of epidermal growth factor receptor protein by using an antibody that detects the cytoplasmic domain of epidermal growth factor receptor; and comparing the level of expression of epidermal growth factor receptor protein in the patient's tumor so measured with a reference value; wherein if the level of expression of epidermal growth factor receptor measured is higher than the reference value, treating the patient with a therapy other than trastuzumab.
    Type: Application
    Filed: December 5, 2013
    Publication date: June 19, 2014
    Applicant: YALE UNIVERSITY
    Inventors: David L. RIMM, Huan CHENG, Anastasios DIMOU, Valsamo ANAGNOSTOU