Patents by Inventor Anat A. Herskovits

Anat A. Herskovits has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10449241
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: October 22, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20180140692
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: January 4, 2018
    Publication date: May 24, 2018
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Patent number: 9895433
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: February 20, 2018
    Assignee: The Regents of the University of California
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20160303212
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: June 24, 2016
    Publication date: October 20, 2016
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Patent number: 9381236
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: July 5, 2016
    Assignee: The Regents of the University of California
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20150297701
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: June 16, 2015
    Publication date: October 22, 2015
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Patent number: 9066900
    Abstract: Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: June 30, 2015
    Assignee: The Regents of the University of California
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20140186392
    Abstract: Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: December 11, 2013
    Publication date: July 3, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Patent number: 8679476
    Abstract: Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: March 25, 2014
    Assignee: The Regents of the University of California
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20130071433
    Abstract: Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: August 31, 2012
    Publication date: March 21, 2013
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Patent number: 8277797
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: October 2, 2012
    Assignee: The Regents of the University of California
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins
  • Publication number: 20100285067
    Abstract: Mutant Listeria bacteria that modulate interferon-? production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
    Type: Application
    Filed: November 21, 2007
    Publication date: November 11, 2010
    Inventors: Daniel A. Portnoy, Anat A. Herskovits, Gregory Crimmins