Abstract: The present disclosure concerns a sensor for detecting a sample analyte having an oxidizable phenolic group suspected to be present in a sample. The sensor comprises a sensing electrode, a plurality of sensor analytes associated with the sensing electrode, optionally a baseline electrode, and a sample receiving region in fluid communication with the sensing electrode. The sensor analyte, before its association with the sensing electrode, is the same chemical species as the sample analyte.

Abstract: Composite nanomaterials including a carbon nanomaterial and an electrocatalyst are disclosed and shown to facilitate enhanced detection, via electro-oxidation, of phenolic analytes when applied to a sensing electrode, such as the working electrode of an electrochemical sensor. In other example embodiments, methods and devices for improved electrochemical detection of phenolic analytes are disclosed in which a sensor electrode is modified by the presence of graphene nanosheets. Such modified electrodes may be employed to provide working electrodes in electrochemical sensors for the rapid detection of cannabinoids and/or associated metabolites in saliva. In some example implementations, the nanocomposite or graphene nanosheets are functionalized with magnetic particles and provided in a suspension that is initially contacted with the sample prior to being magnetically drawn to the surface of the electrode for electrochemical processing.

Abstract: Nanozymes capped with a radical-scavenging capping agent are disclosed for use in biosensing assays with improved sensitivity. The radical-scavenging capping agent facilitates the capture and retention of one or more radicals for enhancing a catalytic reaction. In some example embodiments, the nanozyme capped by the radical-scavenging capping agent is capable of catalyzing the decomposition of hydrogen peroxide or molecular oxygen. The capped nanozymes may be incorporated with an electrode, such as the working electrode of an electrochemical sensor, for achieving enhanced catalytic activity and a lower limit of detection. In some example embodiments, the radical-scavenging capping agent is or includes thiocyanate.

Abstract: A system for delivering breathing gas to passengers includes: a face mask including a face part having a breathing cavity, a tube configured to be supplied by pressurized breathing gas, and a reservoir bag disposed between the tube and the face part. A passage connects the reservoir bag to the breathing cavity so that the system is configured to supply the breathing cavity through the reservoir bag. The reservoir bag includes a front portion and a back portion. The front portion is connected to the face mask, and the system has a stowed configuration and a deployed configuration. In the stowed configuration, the reservoir bag is maintained folded between a backing and the face part.

Abstract: Oxygen-delivery systems are described. The systems may supply emergency respiratory gas on demand to aircraft passengers. To reduce risk of blockage of tubes delivering anti-blocking gas to the face masks worn by the passengers, the systems may be designed to provide a continuous trickle flow of respiratory gas, or one or more anti-blocking pulses of gas, into a delivery tube.

Abstract: Nanozymes capped with a radical-scavenging capping agent are disclosed for use in biosensing assays with improved sensitivity. The radical-scavenging capping agent facilitates the capture and retention of one or more radicals for enhancing a catalytic reaction. In some example embodiments, the nanozyme capped by the radical-scavenging capping agent is capable of catalyzing the decomposition of hydrogen peroxide or molecular oxygen. The capped nanozymes may be incorporated with an electrode, such as the working electrode of an electrochemical sensor, for achieving enhanced catalytic activity and a lower limit of detection. In some example embodiments, the radical-scavenging capping agent is or includes thiocyanate.

Abstract: A system for delivering breathing gas to passengers on-board an aircraft, including: a source of breathing gas, at least one face mask for passengers, a reservoir associated with each face mask, a delivery valve for each face mask, the delivery valve being disposed between the source of breathing gas and the reservoir, the reservoir being disposed between the delivery valve and the face mask, a sensor associated with each reservoir and configured to sense a filling of the reservoir, and a controller configured to control the delivery valve in a continuous supply mode to provide a continuous flow of breathing gas to the reservoir and to interrupt the continuous flow of breathing gas when the filing sensed by the sensor is a filling threshold.

Abstract: A discharge device (1) comprising a housing (200), a container insert (300) rotatably arranged therein and a piston. A lateral cutout (205) is formed in one housing wall (204), and a lateral container opening (303) is formed in one container wall (304). In order to prevent the compound from being compressed as the compound is discharged, the lateral container opening extends continuously as far as the distal container end (302) without a region of the container wall adjoining the lateral container opening in the distal direction along the longitudinal axis. In order to make it easier to put in the compound, the wall thickness of the housing wall decreases continuously toward the lateral cutout (205). In order to prevent clogging of the piston, the cross section of the container insert widens continuously in the distal direction.

Abstract: A system for delivering breathing gas to passengers on-board an aircraft, comprising: a source of breathing gas, at least one face mask for passengers, a reservoir associated with each face mask, a delivery valve for each face mask, the delivery valve being disposed between the source of breathing gas and the reservoir, the reservoir being disposed between the delivery valve and the face mask, a sensor associated with each reservoir and configured to sense a filling of the reservoir, and a controller configured to control the delivery valve in a continuous supply mode to provide a continuous flow of breathing gas to the reservoir and to interrupt the continuous flow of breathing gas when the filing sensed by the sensor is a filling threshold.

Abstract: Oxygen-delivery systems are described. The systems may supply emergency respiratory gas on demand to aircraft passengers. To reduce risk of blockage of tubes delivering anti-blocking gas to the face masks worn by the passengers, the systems may be designed to provide a continuous trickle flow of respiratory gas, or one or more anti-blocking pulses of gas, into a delivery tube.

Abstract: This invention relates to a discharge device of the dispenser gun type, which is suitable in particular for discharging semi-solid materials such as e.g. bone replacement materials. The discharge device comprises an adapter (400) which is removably attached to a main body (110) of the discharge device. A fastening structure for attachment of a container (300) is formed on the adapter substantially along a proximal direction (C) contrary to the feed direction (A). As a result various types of containers can be fastened to the machine without the need to change the mechanism of the device. The container can be provided on both ends with identical external threads and can be closed by closure caps in order to enable intuitive handling. In order to improve access to points which are difficult to reach, the container may be in the form of a curved pipe or may be formed flexibly. The piston rod (200) of the discharge device is then also formed flexibly.

Abstract: A discharge device (1) comprising a housing (200), a container insert (300) rotatably arranged therein and a piston. A lateral cutout (205) is formed in one housing wall (204), and a lateral container opening (303) is formed in one container wall (304). In order to prevent the compound from being compressed as the compound is discharged, the lateral container opening extends continuously as far as the distal container end (302) without a region of the container wall adjoining the lateral container opening in the distal direction along the longitudinal axis. In order to make it easier to put in the compound, the wall thickness of the housing wall decreases continuously toward the lateral cutout (205). In order to prevent clogging of the piston, the cross section of the container insert widens continuously in the distal direction.

Abstract: This invention relates to a discharge device of the dispenser gun type, which is suitable in particular for discharging semi-solid materials such as e.g. bone replacement materials. The discharge device comprises an adapter (400) which is removably attached to a main body (110) of the discharge device. A fastening structure for attachment of a container (300) is formed on the adapter substantially along a proximal direction (C) contrary to the feed direction (A). As a result various types of containers can be fastened to the machine without the need to change the mechanism of the device. The container can be provided on both ends with identical external threads and can be closed by closure caps in order to enable intuitive handling. In order to improve access to points which are difficult to reach, the container may be in the form of a curved pipe or may be formed flexibly. The piston rod (200) of the discharge device is then also formed flexibly.

Abstract: An applicator for spraying at least two components in the interior of the body of a patient uses a compressed gas, the applicator being suitable in particular for laparoscopic applications. The applicator has a connecting piece for connection of the applicator to two reservoirs for the components and for delivery of a compressed gas. A multi-lumen tube extends from the connecting piece to a spray head. A flexible wire is fixed in a first lumen which extends off-center. The applicator has at least one adapter having two tube connectors which are introduced into two further lumina. These two further lumina likewise extend off-center and are offset in the circumferential direction from the lumen which receives the wire. A further lumen can extend centrally and can receive a second wire. Identical adapters can be provided at both ends of the multi-lumen tube.

Abstract: This invention relates to a discharge device of the dispenser gun type, which is suitable in particular for discharging semi-solid materials such as e.g. bone replacement materials. The discharge device comprises an adapter (400) which is removably attached to a main body (110) of the discharge device. A fastening structure for attachment of a container (300) is formed on the adapter substantially along a proximal direction (C) contrary to the feed direction (A). As a result various types of containers can be fastened to the machine without the need to change the mechanism of the device. The container can be provided on both ends with identical external threads and can be closed by closure caps in order to enable intuitive handling. In order to improve access to points which are difficult to reach, the container may be in the form of a curved pipe or may be formed flexibly. The piston rod (200) of the discharge device is then also formed flexibly.

Abstract: The invention relates to a device for removing a fluid from at least one container (300), from a vial for example, said container being closed by a closure (320) that can be punctured. The device comprises a base body (271) with a container receiving portion (272) and a hollow needle-like puncturing organ (277) in order to puncture the closure (320) of the container (300) in a removal position of the container (300). The aim of the invention is to enable mounting the container on the device without unintentionally puncturing the closure. This is achieved in that detent structures (274, 275) are provided which retain the container (300) on the device in a removal position and in a mounting position which is different from said removal position. Such a device can be used in particular to fill an applicator (280) with one or more fluid reservoirs from one or more vitals.

Abstract: A mixing device which can be connected to a discharge unit and is provided to mix one or more substances together as they are discharged from the discharge unit. The mixing device has a base element with a circumferential side wall and an insert which can be inserted into the base element in such a manner that at least one circumferential zone of said insert lies against the side wall of the base element in a sealing manner. A mixing structure with mixing channels is formed on the insert, through which mixing structure the substances can be discharged from the discharge unit.

Abstract: Proposed are a medical spray head (300) for spraying one or more fluid substances with the use of a compressed gas, a spray device equipped therewith, and a method for using the same. In order to avoid too high a gas pressure, the spray head comprises a pressure relief valve (310) which guides the compressed gas out of the spray head if the gas pressure exceeds a threshold pressure. As a result, the risk of gas embolisms occurring during the use of such a spray head for medical purposes is reduced.

Abstract: The invention relates to a discharge device (1) comprising a tank housing (3) having at least one outlet (4) at one end and having a drive means at the opposite end. A connector (6) can be placed over the outlet (4) on the discharge device. The connector comprises a releasable mounting device that can be released by manual pressure on two opposite side surfaces of the connector. One guide surface (9) is provided on each of the two opposite side surfaces, each being oriented diagonally to the longitudinal axis (L) of the discharge device (1) and spaced in the direction of the discharge device. The connector is placed over the outlet on the discharge device in a mounting position. The guide surfaces (9) are moved radially toward each other in a released position by pressure (F) on the side surfaces.

Abstract: A mixing and discharging device (1) has a syringe-like container (10), in which a plunger can be moved. A press-out spindle (30) having an external thread (31) interacts with a counterpart (40) by means of a thread engagement. The counterpart comprises one or more thread segments, which can be deflected outward in order to release the thread engagement. A securing element (5) can be slid onto the counterpart (40) in a distal direction in order to prevent a release of the thread engagement. A mixing rod (61) extends through the plunger (20). An operating element (70) is connected to the proximal end of the mixing rod by means of a releasable form closure or force closure. A locking element (80) can be moved between a locking position and a release position. In the locking position, the locking clement prevents a release of the form closure or force closure. Insulating ribs (13) minimise the input of heat into the interior of the container due to touching.