Abstract: The present application relates to a compound serving as a selective PI3K? kinase inhibitor, comprising the compound shown in formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof, wherein X, R1, R2, R3, R4, R5 and R6 are as defined in the description. The present application also relates to a method for using the kinase inhibitor to inhibit PI3K? kinase activity or to treat or prevent diseases or conditions associated with tyrosine kinase activity of PI3K?, as well as a use thereof.

Abstract: A semiconductor device includes a substrate having a magnetic random access memory (MRAM) region and a logic region, a first metal interconnection on the MRAM region, a second metal interconnection on the logic region, a stop layer extending from the first metal interconnection to the second metal interconnection, and a magnetic tunneling junction (MTJ) on the first metal interconnection. Preferably, the stop layer on the first metal interconnection and the stop layer on the second metal interconnection have different thicknesses.

Abstract: A multi-environment integrative thermal management method for a fuel cell vehicle is provided. The method can ensure the accuracy and the stability of the control for a temperature of a fuel cell system of the fuel cell vehicle in a complicated and changeable environment, decrease the energy consumption of the entire vehicle, and increase the economical efficiency of the entire vehicle.

Abstract: A fiber optic ferrule sub-assembly for insertion into an outer housing of a fiber optic connector includes a ferrule assembly having a ferrule that forms an optical communication connection with another fiber optic device. A back housing includes a back post to be attached to a fiber optic cable. A spring is operatively disposed between the ferrule assembly and the back housing. A linkage connects the ferrule assembly to the back housing such that the spring is compressed and biases the ferrule away from the back housing prior to insertion of the fiber optic ferrule sub-assembly into the outer housing.

Abstract: A user equipment (UE) apparatus for wireless communication with a base station is provided. The UE includes a transceiver and a processor. The processor is configured to transmit, to the base station, via the transceiver, at least one uplink (UL) data packet in a radio resource control (RRC) inactive state based on a preconfigured UL resource (PUR) configuration, wherein the PUR configuration is defined according to a set of PUR parameters, wherein the set of PUR parameters include at least one of a control resource set (CORESET) configuration including an aggregation level and repetition types; a physical UL shared channel (PUSCH) repetition configuration including a frequency hopping pattern; or a UL narrow beam direction for frequency range 2 (FR2) or a transmission reception point (TRP) association, and wherein the set of PUR parameters is associated with new radio (NR).

Abstract: Semiconductor device structures and methods for manufacturing the same are provided. The semiconductor device structure includes a substrate, a die and a stiffener. The substrate has an upper surface. The die is disposed on the upper surface of the substrate. The stiffener is disposed on the upper surface of the substrate and surrounds the die. The stiffener has a first upper surface adjacent to the die, a second upper surface far from the die and a lateral surface extending from the first upper surface to the second upper surface. A first distance between the first upper surface of the stiffener and the upper surface of the substrate is less than a second distance between the second upper surface of the stiffener and the upper surface of the substrate.

Abstract: An optical system is provided. The optical system includes a fixed portion and a movable portion. The movable portion is movable relative to the fixed portion and includes: a first movable portion and a second movable portion. The first movable portion is configured to connect a first optical element. The second movable portion is configured to connect a second optical element and is movable relative to the first movable portion. The movable portion also includes a third optical element disposed corresponding to the first optical element and the second optical element. Light passes through the first optical element, the second optical element and the third optical element.

Abstract: The present disclosure provides methods, devices, apparatus, and storage medium for determining a target image region of a target object in a target image. The method includes: obtaining a target image comprising a target object; obtaining an original mask and an image segmentation model, the image segmentation model comprising a first unit model and a second unit model; downsampling the original mask based on a pooling layer in the first unit model to obtain a downsampled mask; extracting region convolution feature information of the target image based on a convolution pooling layer in the second unit model and the downsampled mask; updating the original mask according to the region convolution feature information; and in response to the updated original mask satisfying an error convergence condition, determining a target image region of the target object in the target image according to the updated original mask.

Abstract: Apparatuses, systems, and techniques are described to determine locations of objects using images including digital representations of those objects. In at least one embodiment, a gaze of one or more occupants of a vehicle is determined independently of a location of one or more sensors used to detect those occupants.

Abstract: Techniques for replicating data involve: acquiring a first snapshot of a data block set, the first snapshot being a snapshot before a first subset of the data block set starts to be replicated; acquiring a second snapshot of the data block set, the second snapshot being a snapshot of the data block set when replication of the first subset is completed; and determining, based on a difference between the second snapshot and the first snapshot, a second subset of the data block set, the second subset being different from the first subset. Accordingly, such techniques can improve data protection efficiency in asynchronous replication.

Abstract: An application program updating method, apparatus, system, medium and device. The application program updating method provides a method of debugging a to-be-updated program logic through a development mode of a hot-update supporting client to obtain an updated program logic, then issuing the updated program logic to a back-end, and acquiring update data from the back end through a product mode of the hot-update supporting client. This allows a front-end developer to write and update simply and quickly without an assistance of any back-end developers.

Abstract: A display screen and an electronic device are disclosed. The display screen has a first display region and a second display region. The display screen includes an anode layer, a pixel defining layer disposed on the anode layer, a number of isolation pillars disposed on the pixel defining layer, and a driving layer group. The pixel defining layer and the isolation pillars form a sub-pixel isolation structure, and the isolation pillars, the pixel defining layer, the driving layer group, and the anode layer are disposed in the first display region and the second display region. The second display region has a vacant region corresponding to a region forming the isolation pillar and without the isolation pillar formed therein, and the pixel defining layer is provided with an opening under the vacant region.

Abstract: The present invention relates to a salt of a compound of formula (I) and uses thereof in medicine. Specifically, it relates to maleate of compound of formula (I) and pharmaceutically compositions thereof. Furthermore, the invention relates to the uses of maleate herein and pharmaceutically compositions thereof disclosed herein in the manufacture of a medicament, especially in the manufacture of a medicament for preventing, managing, treating or lessening hepatitis C virus (HCV) infection.

Abstract: A compound has a structure of Formula (I) below, wherein E represents a 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide functional group or a diphenylphosphine oxide functional group. Moreover, a method of making the compound of Formula (I), a resin composition including the compound of Formula (I) and a resin additive and an article made from the resin composition are described. The article includes a prepreg, a resin film, a laminate or a printed circuit board, wherein one or more properties including copper foil peeling strength, Z-axis ratio of thermal expansion, glass transition temperature, flame retardancy, thermal resistance after moisture absorption, dielectric constant, and dissipation factor may be improved.

Abstract: A human behavior recognition method, a device, and a storage medium are provided, which are related to the field of artificial intelligence, specifically to computer vision and deep learning technologies, and applicable to smart city scenarios. The method includes: obtaining attribute information of a target object and N pieces of candidate behavior-related information of a target human from a target image, wherein N is an integer greater than or equal to 1; determining target behavior-related information based on comparison results between the N pieces of candidate behavior-related information and the attribute information of the target object; and determining a behavior recognition result of the target human based on the target behavior-related information.

Abstract: A screen comprises the following layers sequentially stacked from an incident side of projected light rays: a micro-lens layer, a transparent matrix layer, a total internal reflection layer, and a light-absorbing layer. The light-absorbing layer absorbs light passing through the micro-lens layer, the transparent matrix layer, and the total internal reflection layer. The micro-lens layer comprises a plurality of micro-lens units. The total internal reflection layer comprises a plurality of microstructure units. The microstructure unit has a lower first flat surface and an upper second flat surface. The first flat surface intersects the second flat surface. The plurality of microstructure units forms a serrated structure. The micro-lens units and the microstructure units are at least partially arranged in an alternating manner. The projected light rays converged toward the first flat surface exit after being totally internally reflected by the first flat surface and the second flat surface sequentially.

Abstract: Methods and systems for enhancing cell populations such as chondrocytes for tissue engineering applications, e.g., for production of neocartilage. The methods and systems of the present invention feature the introduction of a hypotonic buffer to the cells during the cell isolation process, which results in neotissue (e.g., neocartilage) constructs that are significantly more mechanically robust as compared to those not treated with hypotonic buffer. The methods and systems may further comprise introducing cytochalasin D to cells purified with a hypotonic buffer, which can further bolster the mechanical properties and matrix deposition of the cells. The methods and systems result in neocartilage engineered from chondrocytes, for example, from fetal aged tissue, having compressive properties on par with native adult articular cartilage.

Abstract: A video processing method, an electronic device and a storage medium are provided, and relate to the field of artificial intelligence, and particularly relates to the fields of deep learning, model training, knowledge mapping, video processing and the like. The method includes: acquiring a plurality of first video frames, and performing fine-grained splitting on the plurality of first video frames to obtain a plurality of second video frames; performing feature encoding on the plurality of second video frames according to multi-mode information related to the plurality of second video frames, to obtain feature fusion information for characterizing fusion of the multi-mode information; and performing similarity matching on the plurality of second video frames according to the feature fusion information, and obtaining a target video according to a result of the similarity matching.

Abstract: A method for metallizing plastic by pre-plating for electroplating, forming a metal bonding layer and a metal transition layer using electro arc ion plating or magnetron sputtering in series, and then forming a metal conductive layer on the metal transition layer using the electro arc ion plating. At least forming the metal conductive layer comprises: disposing a magnetic filter device between a metal target and a vacuum chamber in which the plastic workpiece is placed, so that positively charged metal ions generated by the metal target are deflected by the magnetic filter device and then enter the vacuum chamber to be deposited on the surface of the plastic workpiece.

Abstract: A method of coating a high-pressure fluid vessel comprises filling a high-pressure fluid vessel with a coating solution, draining the coating solution, and drying a remainder of the coating solution in the high-pressure fluid vessel. The coating solution may include a thermoplastic elastomer that is hard with a low glass transition temperature and a high melting temperature. Drying the remainder of the coating solution may form a food grade coating within the high-pressure fluid vessel.