Abstract: A long twist drill includes a shank and a drill body having a drill tip (16). The twist drill has a length L and an outer diameter D, and has a cemented carbide or high speed steel substrate and a coating of at least one layer. The quota L/D is at least 16. The twist drill has two cutting segments at the tip and two flutes chip. The twist drill is provided with holes for fluid opening in the tip. The twist drill has an axial web thinning angle GAA, which is 40 to 50°. The twist drill further has a web that back tapers such that a web diameter gets smaller in a direction away from the tip towards the shank within an axial distance.

Abstract: A long twist drill includes a shank and a drill body having a drill tip (16). The twist drill has a length L and an outer diameter D, and has a cemented carbide or high speed steel substrate and a coating of at least one layer. The quota L/D is at least 16. The twist drill has two cutting segments at the tip and two flutes chip. The twist drill is provided with holes for fluid opening in the tip. The twist drill has an axial web thinning angle GAA, which is 40 to 50°. The twist drill further has a web that back tapers such that a web diameter gets smaller in a direction away from the tip towards the shank within an axial distance.

Abstract: A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; and at least one pharmaceutical excipient; said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.

Abstract: A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; and at least one pharmaceutical excipient; said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.

Abstract: A method for milking animals in a milking station (9) including a milking machine (14) for milking said animals, and a first feeding device (21) for feeding said animals intermittently or continuously with feed, is disclosed, the method comprising the steps of allowing a milking animal to enter the milking station (9); feeding the milking animal in the milking station intermittently or continuously with feed by means of the first feeding device (21); and milking the milking animal in the milking station (9) by means of the milking machine (14). According to the present invention, the feeding of the milking animal is terminated at a non-final stage of the milking in order to secure that the milking animal has terminated to consume the feed when the milking is finished.

Abstract: The present invention relates to a tool as well as a blank for manufacturing of the tool. The tool is made of solid cemented carbide and includes a shank for mounting in a rotatable spindle and chip flutes. Lines of intersection between the chip flutes and clearance surfaces form cutting edges at a cutting end of the tool. The flush channels extend through the entire tool in order to transfer flushing medium to the cutting end of the tool. The flush channels have varying pitch.

Abstract: A compound of formula (I) wherein R is methyl, ethyl, n-propyl, iso-propyl, n-butyl or allyl; R? is hydrogen, C1-C4 alkyl, C1-C3 alkoxy; halogen, trifluoromethyl or OCHxFy, R? is hydrogen, fluoro or chloro, that R? being fluoro or chloro only when R? is fluoro or chloro; R3 is hydrogen or C1-C5 alkyl R4 is hydrogen, CH2OCOC(CH3)3, pharmaceutically acceptable inorganic or organic cations, or COR4? wherein R4? is C1-C5 alkyl, phenyl, benzyl or phenethyl; R7 is methyl or ethyl; one of A and B is sulphur and the other is C—R2; when A is S, R2 is selected from hydrogen and methyl, with the proviso that R2 is methyl only when R3 is not hydrogen; and when B is S, R2 is hydrogen; and any tautomer thereof. A pharmaceutical composition comprising a compound of formula (I), a method of treating malignant tumours or diseases resulting from autoimmunity or pathologic inflammation.

Abstract: A stable solid pharmaceutical composition consisting essentially of an effective amount of a salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; and at least one pharmaceutical excipient; said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.

Abstract: The invention relates to a device and a method for allowing performance of several separate treatments of a teat of an animal. The device comprises a cup-shaped body (1) having a surface (2) defining an inner space (3), which is arranged to receive a teat of the animal. The device comprises also first means arranged to provide a first treatment by supplying a first medium (4) to the teat via at least a first passage having a plurality of openings (10, 18) to the inner space (3) and at least one additional means arranged to provide an additional treatment by supplying an additional medium (13, 26, 28) to the teat, via at least an additional passage having a plurality of openings (10, 18) to the inner space (3). Thereby, the device provides at least two different treatments of the teats at different occasions.

Abstract: A method and system for controlling the cooling of small milk quantities in a cooling tank (2) having a bottom wall portion (12) with a milk cooling surface (12′) within the tank being part of a cooling circuit an agitator (19) within the tank for stirring the milk therein. The gist of the invention is a) providing an element for measuring the milk quantity in the tank, and a temperature transducer (11) for monitoring the milk temperature in the tank, b) providing, in the cooling circuit, an evaporator (4) connected to the bottom wall portion of the tank, a compressor (5), and a condenser (7), c) controlling the temperature of the refrigerant in the evaporator by regulating the vaporizing pressure, so that the temperature of the milk cooling surface (12′) is always higher than 0° C. when the compressor (5) is running, d) monitoring the milk quantity in the tank, and, when sufficient/insufficient for the agitator to work properly.

Abstract: A system for controlling the cooling of small milk quantities in a cooling tank (4). An agitation pipe (2) extended through a regular milk outlet (26) in a first end wall (6) of the tank is provided, having a nozzle end (32) for introducing incoming/re-circulated milk onto a milk cooling surface (14) at a predetermined position (dp). The position (dp) being situated (1) between a first end wall (6) and a central part of the tank (4) and laterally displaced (b) relative to the perpendicular central axis of the tank. The nozzle end (32) is directed towards a second end wall (8) of the tank (4). Agitation is performed by the agitation pipe (2) upon demand or when the milk quantity is insufficient for a regular agitator element (27) to work properly.

Abstract: The present invention refers to an apparatus (11) and a method for milk filtration and filter regeneration. The apparatus comprises a filter vessel (13); a loose filter material (37) housed within the vessel for filtering out contaminants in the milk; and a grid (31) arranged in front of the milk flow outlet to prevent the loose filter material from leaving the vessel. The vessel includes inner walls (15, 17); a milk inlet (21); a milk outlet (23); a cleaning fluid inlet (23) arranged substantially vertically at the lowermost portion of the vessel, through which a cleaning fluid jet can be injected, and a cleaning fluid outlet (21) arranged at the upper portion of the vessel. The lower portions (17) of the inner walls of the vessel form an angle (&agr;) with respect to the horizontal plane, the angle being larger than the angle of repose for the filter material in the cleaning fluid.

Abstract: A method and system for controlling the cooling of small milk quantities in a cooling tank (2) having a bottom wall portion (12) with a milk cooling surface (12′) within the tank being part of a cooling circuit, an agitator means (19) within the tank for stirring the milk therein. The gist of the invention is: a) providing a means (10) for measuring the milk quantity in the tank, and a temperature transducer (11) for monitoring the milk temperature in the tank, b) providing, in the cooling circuit, an evaporator (4) connected to the bottom wall portion of the tank, a compressor (5), and a condenser (7), c) controlling the temperature of the refrigerant in the evaporator by regulating the vaporizing pressure, so that the temperature of the milk cooling surface (12′) is always higher than 0° C., whereas the refrigerant temperature in the evaporator (4) is below O° C.

Abstract: An apparatus for automatically milking an animal, comprising at least one teatcup having a teat entrance end (17a), and a movable arm (6, 40) for moving the teatcup toward a teat of an animal to be milked and attaching it thereto. The teat entrance end of the teatcup is arranged, while being moved by the movable arm (6, 40) toward the teat, to be held in relation to the movable arm (6, 40) at a level which is different from that of the teat entrance end (17a) of a further teatcup, when held in relation to the movable arm.

Abstract: A method for milking and after-treating an animal by using an automatic milking system comprising means for locating the teats of the animal, means for milking the animal and means for performing an after-treatment of the animal. The method comprises an additional step of locating at least one teat of the animal a second time, the additional step being performed prior to the step of performing an after-treatment operation.

Abstract: A method for stimulation of transcription factor AP (activator protein)-1 by administering a compound of the formula (I) wherein R is selected from methyl, ethyl, n-propyl, iso-propyl, c-propyl, n-butyl, sec.-butyl, iso-butyl, tert.-butyl, c-butyl, n-pentyl, sec.-pentyl, iso-pentyl, tert.-pentyl, neo-pentyl, c-pentyl, c-hexyl and c-heptyl; RNa and RNb are the same or different and selected from hydrogen, methyl and ethyl; R2, R3, R5 and R6 are independently selected from hydrogen, methyl, methoxy, thiomethyl, hydroxy, fluoro, chloro, bromo, trifluoromethyl, phenyl and benzyl; n is 1, 2 or 3; R′ and R″ are the same or different and selected from methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec.-butyl, and iso-butyl or R′ and R″ together form a saturated heterocyclic ring of 5-7 atoms; and pharmaceutically acceptable salts, hydrates and solvates thereof, to a mammal in need thereof.

Abstract: Compounds of formula (I) 1

Abstract: The invention is related to compounds of general formula (I) 1

Abstract: A method for stimulation of transcription factor AP (activator protein)-1 by administering a compound of the formula (I) 1

Abstract: The invention is related to compounds of general formula (I) wherein R is methyl, ethyl, n-propyl, iso-propyl, n-butyl or allyl; R' is methyl, methoxy, fluoro, chloro, bromo, trifluoromethyl, or OCH.sub.x F.sub.y, whereinx=0-2, y=1-3 with the proviso that x+y=3, R" is hydrogen, fluoro or chloro; with the proviso that R" is fluoro or chloro only when R' is fluoro or chloro; R.sub.4 is hydrogen or pharmaceutically acceptable inorganic or organic cations;R.sub.5 is ethyl, n-propyl, iso-propyl, methoxy, ethoxy, chloro, bromo, trifluoromethyl, OCH.sub.x F.sub.y, or OCH.sub.2 CH.sub.x F.sub.y wherein x=0-2, y=1-3 with the proviso that x+y=3;R.sub.6 is hydrogen; or R.sub.5 and R.sub.6 taken together are methylenedioxy; and any tautomer thereof.The invention also relates to pharmaceutical compositions containing a compound of the general formula (I) together with a pharmaceutically acceptable carrier.