Patents by Inventor Anders Dybdal Nielsen

Anders Dybdal Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LOW VISCOSITY COMPOSITIONS COMPRISING A PEGYLATED GLA-DOMAIN CONTAINING PROTEIN
    Publication number: 20160151464
    Abstract: The present invention relates to a method for lowering the viscosity of compositions comprising Vitamin K-dependent proteins.
    Type: Application
    Filed: February 4, 2016
    Publication date: June 2, 2016
    Inventors: Anders Dybdal Nielsen, Tina Oestergaard
  • High concentration factor VII polypeptide formulations comprising an aromatic preservative and an antioxidant
    Patent number: 9186323
    Abstract: The present invention relates to pharmaceutical compositions comprising: (i) at least 10 mg/mL of a Factor VII polypeptide; (ii) a buffering agent suitable for keeping pH in the range of from about 5.0 to about 9.0; (iii) at least one aromatic preservative in a concentration of at least 0.1 mg/mL; and (iv) at least one antioxidant in a concentration of at least 0.1 mg/mL; the composition optionally comprising further components, with the proviso that such further components are not Factor VII polypeptide stabilizing agents selected from (a) metal-containing agents, wherein said metal is selected from the group consisting of first transition series metals of oxidation state +II, except zinc; and (b) stabilizing agents comprising a —C(?N—Z1-R1)-NH—Z2-R2 motif.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: November 17, 2015
    Assignee: Novo Nordisk Healthcare AG
    Inventors: Christian Rischel, Michael Bech Jensen, Anders Dybdal Nielsen
  • LOW VISCOSITY COMPOSITIONS COMPRISING A PEGYLATED GLA-DOMAIN CONTAINING PROTEIN
    Publication number: 20110112029
    Abstract: The present invention relates to a method for lowering the viscosity of compositions comprising Vitamin K-dependent proteins.
    Type: Application
    Filed: May 22, 2009
    Publication date: May 12, 2011
    Applicant: Novo Nordisk Health Care AG
    Inventors: Anders Dybdal Nielsen, Tina Østergaard
  • High Concentration Factor VII Polypeptide Formulations Comprising an Aromatic Preservative and an Antioxidant
    Publication number: 20100294677
    Abstract: The present invention relates to pharmaceutical compositions comprising at least 10 mg/mL of a Factor VII polypeptide (i); a buffering agent (ii) suitable for keeping pH in the range of from about 5.0 to about 9.0; at least one aromatic preservative (iii) in a concentration of at least 0.1 mg/mL; and at least one antioxidant (iv) in a concentration of at least 0.1 mg/mL; the composition optionally comprising further components, with the proviso that none of such further components are Factor VII polypeptide stabilizing agents selected from (a) metal-containing agents, wherein said metal is selected from the group consisting of first transition series metals of oxidation state +II, except zinc; and (b) stabilising agent comprising a —C(?N—Z1-R1)-NH—Z2-R2 motif.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 25, 2010
    Applicant: Novo Nordisk Health Care AG
    Inventors: Christian Rischel, Michael Bech Jensen, Anders Dybdal Nielsen