Patents by Inventor Anders Grubb

Anders Grubb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9169289
    Abstract: Compounds of formula R1-A-NH—CH(R2)—CO—R3 are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: October 27, 2015
    Assignee: STRONGBONE AB
    Inventors: Anders Grubb, Franciszek Kasprzykowski, Ulf Lerner, Beata Zolnowska, Regina Kasprzykowska
  • Publication number: 20140243274
    Abstract: Compounds of formula R1-A-NH—CH(R2)—CO—R3 are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.
    Type: Application
    Filed: April 21, 2014
    Publication date: August 28, 2014
    Applicant: Strongbone AB
    Inventors: Anders GRUBB, Franciszek KASPRZYKOWSKI, Ulf LERNER, Beata ZOLNOWSKA, Regina KASPRZYKOWSKA
  • Patent number: 8748370
    Abstract: Novel compounds which may be for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation, bone resorption, or loosening of a prosthetic device.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: June 10, 2014
    Assignee: Strongbone AB
    Inventors: Anders Grubb, Franciszek Kasprzykowski, Ulf Lerner, Beata Zolnowska, Regina Kasprzykowska
  • Patent number: 8268576
    Abstract: A method for diagnosing autism in a subject is performed by determining the presence and concentration of specific peptides in the body fluid. The peptides have the amino acid sequences SKITHRIHWESASLL (SEQ ID NO: 1), SSKITHRIHWESASLL (SEQ ID NO: 2), and SSKITHRIHWESASLLR (SEQ ID NO: 3) with the molecular masses 1779 +/?1 Da, 1865 +/?1 Da and 2022 +/?1 Da, respectively.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: September 18, 2012
    Assignee: Autism Biodiagnostic Ltd
    Inventors: Anders Grubb, Naghi Momeni
  • Publication number: 20120149038
    Abstract: A method for diagnosing autism in a subject is performed by determining the presence and concentration of specific peptides in the body fluid. The peptides have the amino acid sequences SKITHRIHWESASLL, SSKITHRIHWESASLL, and SSKITHRIHWESASLLR with the molecular masses 1779+/?1 Da, 1865+/?1 Da and 2022+/?1 Da, respectively.
    Type: Application
    Filed: June 22, 2011
    Publication date: June 14, 2012
    Inventors: Anders GRUBB, Naghi MOMENI
  • Publication number: 20120108515
    Abstract: Novel compounds which may be for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation, bone resorption, or loosening of a prosthetic device.
    Type: Application
    Filed: June 17, 2010
    Publication date: May 3, 2012
    Applicant: NEOBIOTICS AB
    Inventors: Anders Grubb, Franciszek Kasprzykowski, Ulf Lerner, Beata Zolnowska, Regina Kasprzykowska
  • Patent number: 8097582
    Abstract: A compound having the general formula (I) R1—NH—CH[(CH2)n—NH—C(NH)—NH2]-CO—R2-A-R4; a pharmaceutical composition comprising the compound and use of the compound for the manufacturing of a medicament for the treatment of a disease such as a microbial disease and/or proliferation/stimulation of eukaryotic cells is described.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: January 17, 2012
    Assignee: Neobiotics AB
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalén, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Publication number: 20100247648
    Abstract: The invention relates to compositions comprising a compound based on the general formula (I) R1-Arg-R2—NH—CH(R3)—CH2—NH—R4??(I) The composition may be used to eliminate and/or reduce microorganisms such as bacteria, viruses, fungi and protozoa.
    Type: Application
    Filed: March 8, 2010
    Publication date: September 30, 2010
    Applicant: Neobiotics AB
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalén, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Patent number: 7691805
    Abstract: The invention relates to compositions comprising a compound based on the general formula (I) R1-Arg-R2—NH—CH(R3)—CH2—NH—R4 ??(I) and a carrier, diluent or an excipient.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: April 6, 2010
    Assignee: Neobiotics AB
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalén, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Publication number: 20090118198
    Abstract: The invention relates to a compound having the general formula (I) R1—NH—CH[(CH2)n—NH—C(NH)—NH2]-CO—R2-A-R4; a pharmaceutical composition comprising said compound and use of said compound for the manufacturing of a medicament for the treatment of a disease such as a microbial disease and/or proliferation/stimulation of eukaryotic cells.
    Type: Application
    Filed: May 4, 2007
    Publication date: May 7, 2009
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalen, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Publication number: 20080255055
    Abstract: The invention relates to compositions comprising a compound based on the general formula (I) R1-Arg-R2—NH—CH(R3)—CH2—NH—R4 (I) The composition may be used to eliminate and/or reduce microorganisms such as bacteria, viruses, fungi and protozoa.
    Type: Application
    Filed: November 10, 2005
    Publication date: October 16, 2008
    Applicant: NEOBIOTICS AB
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalen, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Publication number: 20060116327
    Abstract: The invention relates to compositions comprising a compound based on the general formula (I) R1-Arg-R2—NH—CH(R3)—CH2—NH—R4 ??(I) The composition may be used to eliminate and/or reduce microorganisms such as bacteria, viruses, fungi and protozoa.
    Type: Application
    Filed: November 10, 2005
    Publication date: June 1, 2006
    Applicant: Neobiotics AB
    Inventors: Anders Grubb, Aftab Jasir, Claes Schalen, Franciszek Kasprzykowski, Regina Kasprzykowska
  • Patent number: 5432264
    Abstract: A recombinant cystatin C polypeptide or a derivative thereof, such as 3-des-hydroxy-cystatin C, is produced biosynthetically by fermentation of a microorganism into which plasmids containing a DNA-sequence coding for said polypeptide have been introduced. Preparations containing recombinant cystatin C, preferably 3-des-hydroxy-cystatin C, have a higher cystein proteinase inhibitor activity than native cystatin C, isolated from human fluids. Such preparations are useful in therapeutic treatments of patients suffering from different diseases, for example herbes simplex.
    Type: Grant
    Filed: August 13, 1992
    Date of Patent: July 11, 1995
    Assignee: Novo Nordisk A/S
    Inventors: Anders Grubb, Ake Lundwall, Magnus Abrahamson, Henrik Dalboge
  • Patent number: 5037957
    Abstract: New compounds which are cysteine proteinase inhibitors of the formulaB - A - CwhereinB=Pro-Arg-Leu-Val-Gly-, Arg-Leu-Val-Gly-, Leu-Val-Gly-, or Val-Gly-, or zero; the N-terminal amino acid optionally having a protective group,A=a reactive group capable of specifically reacting with free-SH groups,C=-Gly-Pro-Met-Asp-Ala; -Gly-Pro-Met-Asp; -Gly-Pro-Met; or -Gly-Pro, or zero;with the proviso that B and C are not both zero.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: August 6, 1991
    Inventors: Anders Grubb, Magnus Abrahamson, Jerzy Trojnar