Abstract: The present disclosure relates to a fibre reinforced polymer (FRP) tube, the tube comprising a plurality of concentric layers of an FRP material forming a shell of the tube. At least one blind threaded longitudinal bolt hole is provided from a transverse end surface of the shell. The bolt hole extends in at least three of the plurality of layers, a middle layer encompassing a plane passing through a center of the bolt hole, an inner layer encompassing a plane of an innermost extent of the bolt hole, and an outer layer encompassing a plane of an outermost extent of the bolt hole. The fibre filament of each of the inner and outer layers has been wound at a first angle to the longitudinal axis and the fibre filament of the middle layer has been wound at a second angle to the longitudinal axis.

Abstract: Shatter protection for a high voltage apparatus with a ceramic insulator includes at least one electrically insulating tube including a plurality of holes going through an envelope surface. The electrically insulating tube has a diameter such that there is a minimum distance between the tube and the ceramic insulator when arranged concentrically. A method for producing a shatter protection includes winding a first helix shape of the electrically insulating fiber composite material at a first pitch such that there is a first gap between the winding turns, and winding a second helix shape of the electrically insulating fiber composite material onto the first helix shape in the opposite direction and at a second pitch, such that there is a second gap between the winding turns. Thereby forming a first electrically insulating tube with holes formed by the first and second gap between the winding turns.

Abstract: Pallet (1) comprised of at least one loading plane (2), on which goods or the like are placed during use of the pallet, and at least one pallet foot (3) or several pallet feet (3). The loading plane (2) is comprised of at least one first material layer (10) of corrugated fiberboard and at least one second material layer (11) of corrugated fiberboard and at least one third material layer (14) of corrugated fiberboard which are joined together by gluing. The adjacent material layers' corrugated mediums are twisted in relation to one another. The loading plane (2) is further comprised of at least one surrounding covering that encloses or essentially encloses the material layers and that the enclosing covering is comprised of at least one first shroud (8) and at least one second shroud (9) of water repellent or water resistant material. In alternative embodiments, the pallet is comprised of at least one pallet collar (4).

Abstract: The present disclosure relates to a fibre reinforced polymer (FRP) tube, the tube comprising a plurality of concentric layers of an FRP material forming a shell of the tube. At least one blind threaded longitudinal bolt hole is provided from a transverse end surface of the shell. The bolt hole extends in at least three of the plurality of layers, a middle layer encompassing a plane passing through a center of the bolt hole, an inner layer encompassing a plane of an innermost extent of the bolt hole, and an outer layer encompassing a plane of an outermost extent of the bolt hole. The fibre filament of each of the inner and outer layers has been wound at a first angle to the longitudinal axis and the fibre filament of the middle layer has been wound at a second angle to the longitudinal axis.

Abstract: Shatter protection for a high voltage apparatus with a ceramic insulator includes at least one electrically insulating tube including a plurality of holes going through an envelope surface. The electrically insulating tube has a diameter such that there is a minimum distance between the tube and the ceramic insulator when arranged concentrically. A method for producing a shatter protection includes winding a first helix shape of the electrically insulating fiber composite material at a first pitch such that there is a first gap between the winding turns, and winding a second helix shape of the electrically insulating fiber composite material onto the first helix shape in the opposite direction and at a second pitch, such that there is a second gap between the winding turns. Thereby forming a first electrically insulating tube with holes formed by the first and second gap between the winding turns.

Abstract: A packaging unit for hygiene articles, the unit being formed from a sheet of material having a longitudinal direction and a transverse direction. The sheet has an inner surface and an outer surface. The inner surface includes an edge portion being provided with a resealable adhesive for closure of the packaging unit. Furthermore, the sheet has at least one transversely extending folding axis dividing said sheet into a first region and a second region. The sheet is provided with at least one sync mark for indication of a positioning of the sheet of material during manufacturing of the packaging unit, the sync mark being provided on the outer surface. A blank and a method for forming the packaging unit are also provided.

Abstract: An insulator for separating two objects with different electrical potential, the insulator including an insulating body enclosing a first volume for housing a gas, the body being provided with an opening, and a sealing arrangement arranged to seal the opening in the body and including a first gas-tight sealing element for sealing the opening and provided with a first closable opening, and a second gas-tight sealing element for sealing the opening, and arranged inside the first sealing element so that the first and second sealing elements define a second volume significantly smaller than the first volume. The second sealing element is provided with a second closable opening which in cooperation with the first closable opening enable control of the gas pressure in the first volume. Methods for leakage detection of the insulator are also disclosed.

Abstract: An insulator for separating two objects with different electrical potential, the insulator including an insulating body enclosing a first volume for housing a gas, the body being provided with an opening, and a sealing arrangement arranged to seal the opening in the body and including a first gas-tight sealing element for sealing the opening and provided with a first closable opening, and a second gas-tight sealing element for sealing the opening, and arranged inside the first sealing element so that the first and second sealing elements define a second volume significantly smaller than the first volume. The second sealing element is provided with a second closable opening which in cooperation with the first closable opening enable control of the gas pressure in the first volume. Methods for leakage detection of the insulator are also disclosed.

Abstract: The present invention is related to a modified hydroxypolymer conjugates preferably a guanidine-dextran conjugate having a tumor cell killing activity. The modified hydroxypolymer conjugate is used as medicine, particularly for manufacturing a medicine or tumor killing composition for treating tumors. A method for producing said hydroxypolymer conjugate and a method for killing cancer cells and treating tumors is also disclosed. The invention is also related to a method for killing tumor cells and treating tumors by administering an effective amount of the modified hydroxypolymer conjugate.

Abstract: The present invention is related to a modified hydroxypolymer conjugate, preferably a dextran-guanidine-biphosphonate conjugate for treating not only skeletal tumors i.e. bone metastasis, particularly bone metastasis related to hormone refractory prostate cancer HRPC and breast cancer, but also osteoporosis. A method for producing and using said hydroxypolymer conjugate is also disclosed.

Abstract: An actuating system 300 is provided for actuating a plurality of pipettes 1 comprising a bellows portion 13. The actuating system comprises means 360 for receiving the plurality of pipettes and an actuator 320. The receiving means 360 and the actuator 160 are reciprocable relative to one another to compress or decompress the bellows portions of pipettes received in the receiving means in use. The receiving means 360 comprises a plurality of pipette receiving parts in the form of clips 140 each configured to receive a respective pipette having a bellows piece 5 and a dispensing piece 3, wherein each pipette receiving part 140 is arranged to cooperate with the dispensing piece 3 of a respective pipette to mount the pipette to the actuating system. The actuating system further comprises locating means in the form of a guide plate 160 to help maintain alignment of the pipette in use, the locating means cooperating with the bellows piece 5 of each pipette.

Abstract: The present invention is related to a modified hydroxypolymer conjugates preferably a guanidine-dextran conjugate having a tumor cell killing activity. The modified hydroxypolymer conjugate is used as medicine, particularly for manufacturing a medicine or tumor killing composition for treating tumors. A method for producing said hydroxypolymer conjugate and a method for killing cancer cells and treating tumors is also disclosed. The invention is also related to a method for killing tumor cells and treating tumors by administering an effective amount of the modified hydroxypolymer conjugate.

Abstract: The present invention relates to a method of disrupting a conjugate comprising a biotin compound and a biotin-binding compound, said method comprising the step of contacting said conjugate with an effective amount of a substantially aqueous solution under conditions such that the conjugate is disrupted, preferably reversibly disrupted, thereby forming a biotin compound and a biotin-binding compound. In particular, the invention relates to a method of reversibly releasing a biotinylated moiety from a streptavidin (or avidin) coated support. Uses of the methods in techniques of detection, identification, determination, purification, separation and/or isolation of target proteins or nucleic acid molecules are also encompassed by the present invention.

Abstract: The general idea according to the invention is to introduce a special purpose register file (34) adapted for holding memory address calculation information received from memory (50, 70) and to provide one or more dedicated interfaces (73, 74) for allowing efficient transfer of memory address calculation information in relation to the special-purpose register file. The special-purpose register file (34) is preferably connected to at least one functional processor unit (42), which is operable for determining a memory address based on memory address calculation information received from the special-purpose register file (34). Once the memory address has been determined, the corresponding memory access can be effectuated.

Abstract: The present invention relates to a method of disrupting a conjugate comprising a biotin compound and a biotin-binding compound, said method comprising the step of contacting said conjugate with an effective amount of a substantially aqueous solution under conditions such that the conjugate is disrupted, preferably reversibly disrupted, thereby forming a biotin compound and a biotin-binding compound. In particular, the invention relates to a method of reversibly releasing a biotinylated moiety from a streptavidin (or avidin) coated support. Uses of the methods in techniques of detection, identification, determination, purification, separation and/or isolation of target proteins or nucleic acid molecules are also encompassed by the present invention.

Abstract: A compound for local, i.e. intratumoral or intracavitary administration, for targeting tumors comprising dextran, the charge of which has been modified through covalent binding of charged groups, such as charged amino acids. The compound further comprises a functional group for treating or imaging the tumor.

Abstract: Polysaccharide-somatostatin analogs of the formula: wherein the somatostatin analog is directly or indirectly coupled from a terminal N-amino group of the somatostatin analog to a polysaccharide, and the polysaccharide-somatostatin analog is provided with an effective negative charge. The compounds are useful in diagnosing and treating cancers.