Abstract: Disclosed herein is a process for preparing a coffee extract, comprising the steps of: providing a mixture of roasted coffee beans and water, milling the mixture of roast coffee beans and water in a pressurised chamber, and separating the milled mixture in a liquid coffee extract and spent coffee grounds. The coffee extract maintains many of the flavour components of the roasted beans.

Abstract: Disclosed herein is a process for production of an instant coffee product in a high yield, comprising the steps of extracting roast and ground coffee beans with water having a temperature of 80° C. or less, to produce a first extract and spent coffee grounds, adding water to the spent coffee grounds to produce an aqueous suspension, hydrolysing the aqueous suspension using a hydrolysing enzyme to produce a second extract and spent remains, adding the first extract to the second extract, optionally after concentration and/or drying of the second extract, to obtain a combined extract, and drying the combined extract to obtain an instant coffee product. The high yield is obtained due to the reduction of enzyme inhibiting substances.

Abstract: Disclosed herein is a process for production of an instant coffee product in a high yield, comprising the steps of extracting roast and ground coffee beans with water having a temperature of 80° C. or less, to produce a first extract and spent coffee grounds, adding water to the spent coffee grounds to produce an aqueous suspension, hydrolysing the aqueous suspension using a hydrolysing enzyme to produce a second extract and spent remains, adding the first extract to the second extract, optionally after concentration and/or drying of the second extract, to obtain a combined extract, and drying the combined extract to obtain an instant coffee product. The high yield is obtained due to the reduction of enzyme inhibiting substances.

Abstract: Disclosed herein is a process for preparing a coffee extract, comprising the steps of: providing a mixture of roasted coffee beans and water, milling the mixture of roast coffee beans and water in a pressurised chamber, and separating the milled mixture in a liquid coffee extract and spent coffee grounds. The coffee extract maintains many of the flavour components of the roasted beans.

Abstract: The present invention relates to a screw implant (1) for insertion into a bore hole (50) arranged in bone tissue, said implant having a cancellous portion (3), and a cortical portion (2) having an axial length such that, when installed in the bore hole (50), the engagement of said cortical portion (2) with the bone tissue will generally be confined to the cortical bone tissue layer (52). Said cortical portion (2) presents an outer surface which is threaded for accomplishing said engagement, and has an outer design such that, when being screwed into said bore hole under action of a screwing torque, said cortical portion (2) acts so as to increase the compression of the cortical bone tissue only, in essentially radial directions of the implant, resulting in a distinct increase of the screwing torque needed for screwing the implant (1). Said increase is usable as an indication that the implant (1) is in place or nearly in place in the bore hole.

Abstract: The present invention relates to Acetyl Coenzyme A Carboxylase (ACC) inhibitors according to formula (I), or an enantiomer thereof, or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5, E, L, Z and n are as defined herein, to processes for preparing such compounds, to pharmaceutical compositions containing them, to the use of such inhibitors and to methods for their therapeutic use, particularly in the treatments of obesity and diabetes mellitus.

Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S,3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as processes for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.

Abstract: Intermediates used in the preparation of compounds of formula I, or a stereoisomer thereof, or a pharmaceutically acceptable form of either selected from the group consisting of a salt, a solvate and a combination thereof, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S,3R)-(3-amino-2-hydroxybutyl)phosphinic acid.

Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S, 3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as processes for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.

Abstract: The present invention relates to a screw implant (1) for insertion into a bore hole (50) arranged in bone tissue, said implant having a cancellous portion (3), and a cortical portion (2) having an axial length such that, when installed in the bore hole (50), the engagement of said cortical portion (2) with the bone tissue will generally be confined to the cortical bone tissue layer (52). Said cortical portion (2) presents an outer surface which is threaded for accomplishing said engagement, and has an outer design such that, when being screwed into said bore hole under action of a screwing torque, said cortical portion (2) acts so as to increase the compression of the cortical bone tissue only, in essentially radial directions of the implant, resulting in a distinct increase of the screwing torque needed for screwing the implant (1). Said increase is usable as an indication that the implant (1) is in place or nearly in place in the bore hole.

Abstract: Dental implant component (1; 1′) for a dental prosthesis or a core part of a dental prosthesis to be fabricated on comprising a base section (3; 3′) having a proximal end (2; 2′) for engagement with a support end of a support component and a distal end (7; 7′); and an elongate post section (5; 5′) which projects distally from the distal end of the base section and has a transverse dimension which is substantially less than the transverse dimension of the base section. In a first aspect of the invention the dental implant component is made at least in part from a material which is adapted to burn-out during lost-wax casting whereby a dental prosthesis or core part of a dental prosthesis fabricated on the dental implant component by lost wax casting includes at most only a part of the dental implant component. In a second aspect of the invention the elongate post section is positioned offset on the distal end of the base section.

Abstract: A method of treating a patient having a toothless site (10) in a jaw comprising the steps of providing a fixture (1) for anchorage in the bone (5) of the jaw at the toothless site having a coronal end (9); anchoring the fixture in the bone such that the coronal end is submerged beneath the coronal margin (8) of the gingival layer (7) at the toothless site; providing an abutment (31a; 31b; 31c) which is securable in an operational position to the fixture through an opening (12) provided through the gingival layer to the fixture, the abutment having a transgingival structure (37) which comprises an apical section (41) which tapers outwardly from an apical end of the transgingival structure which in the operational position of the abutment is co-planar with the coronal end of the fixture to a position at which the transgingival structure has a maximum transverse dimension and a coronal section (43) contiguous with the apical section which tapers inwardly from the maximum transverse dimension to a coronal end of

Abstract: A set of dental implant components for use in fabricating a dental prosthesis (25) comprising a support component (19) for inclusion in a model of a jaw having a support end (17) and a socket (21); a sleeve cylinder (15) on which the dental prosthesis or a core part of the dental prosthesis is to be fabricated, the sleeve cylinder having a distal end adapted to engage with the support end of the support component, a proximal end and a channel extending from a distal opening in the distal end to a proximal opening in the proximal end; and an access passage-forming post (1) having a distal section (9) which presents a distal end (11) of the post and a proximal section (7) which presents a proximal end (3) of the post, the post being adapted to be disposed in an operational position when the distal end of the sleeve cylinder engages with the support end of the support component in which the distal section (9) of the post is releasably secured in the socket in the support component through the proximal opening of

Abstract: The present invention provides a reaction system for a Fischer-Tropsch synthesis which has high mass transfer characteristics at the catalyst. The reactor comprises a monolithic catalyst comprising a solid body defining discrete and continuous channels extending from one end of the body to the other. The walls of the channels contain a conventional Fischer-Tropsch catalyst; conventional promoters may also be included. The body preferably may also comprises channels for conducting coolants which are arranged traversely to the reaction channels.

Abstract: The present invention relates to a device for determining the correct lengths of standardized components of a dental implant system in situ in the oral cavity. The device comprises an elongate gauge body being provided with circumferential dark bands located at predetermined distances from each other and having predetermined widths, the areas between said darker bands having a pronouncedly lighter color, each boundary line between lighter and darker bands corresponding to one specific, standardized component.

Abstract: The present invention relates to a device for determining the correct lengths of standardized components of a dental implant system in situ in the oral cavity. The device comprises an elongate gauge body being provided with circumferential dark bands located at predetermined distances from each other and having predetermined widths, the areas between said darker bands having a pronouncedly lighter color, each boundary line between lighter and darker bands corresponding to one specific, standardized component.