Patents by Inventor Anders Matthew Knight

Anders Matthew Knight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED URIDINE PHOSPHORYLASE VARIANT ENZYMES
    Publication number: 20240132858
    Abstract: The present invention provides engineered uridine phosphorylase (UP) enzymes, polypeptides having UP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing UP enzymes are also provided. The present invention further provides compositions comprising the UP enzymes and methods of using the engineered UP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
    Type: Application
    Filed: January 3, 2024
    Publication date: April 25, 2024
    Inventors: Jonathan Vroom, Jessica Anna Hurtak, Anders Matthew Knight
  • Engineered uridine phosphorylase variant enzymes
    Patent number: 11898174
    Abstract: The present invention provides engineered uridine phosphorylase (UP) enzymes, polypeptides having UP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing UP enzymes are also provided. The present invention further provides compositions comprising the UP enzymes and methods of using the engineered UP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: February 13, 2024
    Assignee: Codexis, Inc.
    Inventors: Jonathan Vroom, Jessica Anna Hurtak, Anders Matthew Knight
  • ENGINEERED TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE VARIANTS
    Publication number: 20230183663
    Abstract: The present invention provides engineered terminal deoxynucleotidyl transferase (TdT) polypeptides useful in template-independent polynucleotide synthesis using a nucleoside triphosphate-3?-O-removable blocking group (NTP-3?-O-RBG), as well as compositions, methods of utilizing these engineered polypeptides, and polynucleotides encoding the engineered terminal deoxynucleotidyl transferases.
    Type: Application
    Filed: October 13, 2022
    Publication date: June 15, 2023
    Inventors: Charlene Ching, Stephanie Marie Forget, Anders Matthew Knight, Mikayla Jianghongxia Krawczyk, Niusha Mahmoodi, Melissa Ann Mayo, Mathew G. Miller, Jonathan Vroom
  • ENGINEERED URIDINE PHOSPHORYLASE VARIANT ENZYMES
    Publication number: 20220195400
    Abstract: The present invention provides engineered uridine phosphorylase (UP) enzymes, polypeptides having UP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing UP enzymes are also provided. The present invention further provides compositions comprising the UP enzymes and methods of using the engineered UP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 23, 2022
    Inventors: Jonathan Vroom, Jessica Anna Hurtak, Anders Matthew Knight