Abstract: An apparatus for microwave assisted solid phase synthesis using solid-phase resin beads mixed with a liquid solvent comprising a generally cylindrical reactor made of microwave transparent material and having a central axis, the reactor having an inlet and an outlet; a porous frit associated with the outlet of the reactor, the porous frit preventing discharge of beads and allowing discharge of the solvent from the reactor; and means for concentric rotation of the reactor around the central axis in alternating clockwise and anti-clockwise directions. A method for microwave assisted solid phase synthesis using the apparatus is also disclosed.

Abstract: An apparatus for microwave assisted solid phase synthesis using solid-phase resin beads mixed with a liquid solvent comprising a generally cylindrical reactor made of microwave transparent material and having a central axis, the reactor having an inlet and an outlet; a porous frit associated with the outlet of the reactor, the porous frit preventing discharge of beads and allowing discharge of the solvent from the reactor; and means for concentric rotation of the reactor around the central axis in alternating clockwise and anti-clockwise directions. A method for microwave assisted solid phase synthesis using the apparatus is also disclosed.

Abstract: The present invention provides an apparatus that can be used to connect a flash chromatography instrument to a fraction collector and a mass detector to perform mass-directed flash chromatography.

Abstract: Devices and methods for performing microwave-assisted chemical synthesis including heterogeneous starting materials, comprising a reaction vessel (9), a microwave source (3) for generating microwave electromagnetic radiation, means for transporting microwave electromagnetic radiation (5) to said reaction vessel (9), at least one liquid reservoir (45) containing a liquid component, means for transporting a liquid component (43) from a liquid reservoir to said reaction vessel, wherein it further comprises an automated system for dispensing solid starting material (59) into said reaction vessel.