Patents by Inventor Andong Liu

Andong Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240150420
    Abstract: The present disclosure relates to a nucleic acid encoding human HGF and use thereof. The nucleic acid comprises one or more open reading frames (ORFs). The ORF nucleic acid sequence is at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 97%, at least 98%, at least 99% or 100% identical to the nucleic acid sequence of SEQ ID NOs: 21-31. The present disclosure provides a nucleic acid encoding human HGF, as well as a nucleic acid construct, a vector, a cell and a drug which comprise the nucleic acid. The nucleic acid has a protein expression level superior to that of a natural sequence.
    Type: Application
    Filed: March 13, 2023
    Publication date: May 9, 2024
    Inventors: Kai Wang, Jiayan Lang, Shaoli Liu, Zihang Pan, Weijing Kong, Andong Liu
  • Publication number: 20240139116
    Abstract: A nanoparticle preparation system, a control method of the nanoparticle preparation system, an electronic device, a non-transitory computer readable medium, and a method for preparing nanoparticles using the nanoparticle preparation system are disclosed. The nanoparticle preparation system includes a mixing element, a first liquid suction device and a second liquid suction device. The mixing element includes a plurality of mixing channels; the first liquid suction device includes a plurality of first liquid suction tubes arranged in rows along a first direction and configured to input a first preparation solution into the plurality of mixing channels through first inlets of the mixing channels, respectively; and the second liquid suction device includes a plurality of second liquid suction tubes arranged in rows along a second direction and configured to input a second preparation solution into the plurality of mixing channels through second inlets of the mixing channels, respectively.
    Type: Application
    Filed: October 26, 2022
    Publication date: May 2, 2024
    Applicants: Beijing Jitai Pharmaceutical Technology Co., Ltd., Hangzhou Jitai Pharmaceutical Technology Co., Ltd.
    Inventors: Andong Liu, Liu Yang, Tian Jiang, Caida Lai, Wenshou Wang
  • Patent number: 11970601
    Abstract: A thermoplastic polyolefin composition comprises: (A) a polypropylene polymer; (B) an elastomer component; (C) an additive component; and (D) a scavenger component comprising a polyacetoacetate compound having the Formula (I) defined herein and calcium carbonate. And an article is made from the thermoplastic polyolefin composition.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: April 30, 2024
    Assignee: Dow Global Technologies LLC
    Inventors: Haiying Li, Andong Liu, Shaoguang Feng, Xiuhan Yang, Jian Zou, Ming Ming, Yonghua Gong, Xuemei Zhai
  • Publication number: 20230346702
    Abstract: The present disclosure provides a lipid nanoparticle wherein the lipid ingredient comprises a compound of formula (IV). The present disclosure also provides a method of preparing the lipid nanoparticle, a pharmaceutical composition of the lipid nanoparticle, and use of the lipid nanoparticle and pharmaceutical compositions in the delivery of nucleic acids.
    Type: Application
    Filed: January 5, 2023
    Publication date: November 2, 2023
    Inventors: Liu YANG, Le YIN, Andong LIU, Lin ZHANG, Caida LAI, Wenshou WANG
  • Publication number: 20230348361
    Abstract: Provided herein is a class of ionizable lipid compounds represented by formula (IV), or pharmaceutically acceptable salts, isotopic variants, tautomers or stereoisomers thereof. Also provided is a nanoparticle pharmaceutical composition comprising said compound, and the application of said compound and its composition in the delivery of nucleic acids.
    Type: Application
    Filed: January 5, 2023
    Publication date: November 2, 2023
    Inventors: Lin ZHANG, Liu YANG, Andong LIU, Caida LAI, Wenshou WANG
  • Patent number: 11780998
    Abstract: The present disclosure relates to a thermoplastic polyolefin composition comprising: (A) a polypropylene polymer; (B) an elastomer component; (C) an additive component; and (D) a scavenger component comprising a polyacetoacetate compound having the Formula (I) defined herein and an amino alcohol compound having the Formula (II) defined herein. The present disclosure also relates to an article made from the thermoplastic polyolefin composition.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: October 10, 2023
    Assignee: Dow Global Technologies LLC
    Inventors: Haiying Li, Shaoguang Feng, Andong Liu, Yonghua Gong, Jian Zou, Xiuhan Yang, Xuemei Zhai
  • Patent number: 11485840
    Abstract: The present invention provides polymer blends that can be used in a multilayer structure and to multilayer structures comprising one or more layers formed from such blends. In one aspect, a polymer blend comprises (a) a copolymer comprising ethylene and at least one of acrylic acid and methacrylic acid having an acid content of 2 to 21 weight percent based on the weight of the copolymer, wherein the amount of copolymer (a) comprises 20-80 weight percent of the blend based on the total weight of the blend, and (b) a copolymer comprising ethylene and at least one of methyl acrylate and ethyl acrylate having an acrylate content of 5 to 30 weight percent based on the weight of the copolymer, wherein the amount of copolymer (b) comprises 10 to 50 weight percent of the blend based on the total weight of the blend, wherein the amount of copolymer (a) and copolymer (b) is at least 70 weight percent of the blend based on the total weight of the blend.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: November 1, 2022
    Assignee: Dow Global Technologies LLC
    Inventors: Andong Liu, Guihong Liao, Jianping Pan, Peng Gao, Hongyu Chen, Yi Zhang
  • Patent number: 11338563
    Abstract: Provided is a coextruded multilayer film. The coextruded multilayer film has at least two layers, including a sealant layer and a second layer in contact with the sealant layer. The sealant layer contains (A) a first ethylene-based polymer having a density from 0.865 g/cc to 0.930 g/cc and a melt index from 0.5 g/10 min to 25 g/10 min; (B) an unsaturated primary fatty acid amide having a melting point of 100° C. or less; and (C) a diprotic fatty acid having a melting point greater than 100° C. and a decomposition temperature greater than 200° C. The second layer contains a second ethylene-based polymer. Also provided is a laminate containing said sealant layer.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: May 24, 2022
    Assignee: Dow Global Technologies LLC
    Inventors: Fengyi Su, Andong Liu, Hongyu Chen, Jianping Pan, Xiao Bing Yun, Thomas Allgeuer, Erqiang Chen, Tipeng Zhao, Guihong Liao
  • Patent number: 11332602
    Abstract: The disclosure relates to a tie resin formulation with excellent adhesion to polyethylene terephthalate (PET). The resin includes (A) an ethylene acrylate copolymer formed from ethylene and alkyl acrylate, where the ethylene acrylate copolymer has an acrylate content of 10 to 30 weight percent and an ethylene content of 90 to 70 weight percent based on the total weight of the ethylene acrylate copolymer and the acrylate content and (B) a transesterification catalyst; where the resin includes: 30 to 99.999 weight percent of the ethylene acrylate copolymer based on the total weight of the resin; 0.001 to 10 weight percent of the transesterification catalyst based on the total weight of the resin; and (C) 0 to 69.999 of a non-polar polyolefin based on the total weight of the resin.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: May 17, 2022
    Assignee: Dow Global Technologies LLC
    Inventors: Andong Liu, Yunlong Guo, Yong Zheng, Hongyu Chen, Brian Walther, Yi Zhang
  • Publication number: 20220025164
    Abstract: A thermoplastic polyolefin composition comprises: (A) a polypropylene polymer; (B) an elastomer component; (C) an additive component; and (D) a scavenger component comprising a polyacetoacetate compound having the Formula (I) defined herein and an inorganic porous material. The present disclosure also relates to an article made from the thermoplastic polyolefin composition.
    Type: Application
    Filed: November 29, 2018
    Publication date: January 27, 2022
    Inventors: Haiying Li, Shaoguang Feng, Andong Liu, Xiuhan Yang, Jian Zou, Ming Ming, Yonghua Gong, Xuemei Zhai
  • Publication number: 20220010111
    Abstract: The present disclosure relates to a thermoplastic polyolefin composition comprising: (A) a polypropylene polymer; (B) an elastomer component; (C) an additive component; and (D) a scavenger component comprising a polyacetoacetate compound having the Formula (I) defined herein and an amino alcohol compound having the Formula (II) defined herein. The present disclosure also relates to an article made from the thermoplastic polyolefin composition.
    Type: Application
    Filed: November 29, 2018
    Publication date: January 13, 2022
    Inventors: Haiying Li, Shaoguang Feng, Andong Liu, Yonghua Gong, Jian Zou, Xiuhan Yang, Xuemei Zhai
  • Publication number: 20220010112
    Abstract: A thermoplastic polyolefin composition comprises: (A) a polypropylene polymer; (B) an elastomer component; (C) an additive component; and (D) a scavenger component comprising a polyacetoacetate compound having the Formula (I) defined herein and calcium carbonate. And an article is made from the thermoplastic polyolefin composition.
    Type: Application
    Filed: November 29, 2018
    Publication date: January 13, 2022
    Inventors: Haiying Li, Andong Liu, Shaoguang Feng, Xiuhan Yang, Jian Zou, Ming Ming, Yonghua Gong, Xuemei Zhai
  • Publication number: 20220002527
    Abstract: Provided is a thermoplastic polyolefin composition that comprises (A) a polypropylene polymer, (B) an elastomer component, (C) an additive component and (D) a scavenger component. Said scavenger component comprises a polyacetoacetate compound that has the Formula (I) defined herein and a metal oxide. Provided also is an article made from said thermoplastic polyolefin composition.
    Type: Application
    Filed: November 29, 2018
    Publication date: January 6, 2022
    Inventors: Haiying Li, Shaoguang Feng, Andong Liu, Yonghua Gong, Jian Zou, Xiuhan Yang, Takahiko Ohmura
  • Patent number: 11090852
    Abstract: The coextruded multilayer film has at least two layers, including a sealant layer and a second layer in contact with the sealant layer. The sealant layer contains (A) a first ethylene-based polymer having a density from 0.865 g/cc to 0.930 g/cc and a melt index from 0.5 g/10 min to 25 g/10 min; (B) an unsaturated primary fatty acid amide having a melting point of 100° C. or less; and (C) a saturated primary fatty acid amide having a melting point greater than 100° C. The unsaturated primary fatty acid amide and the saturated primary fatty acid amide have a weight ratio of from 3:1 to 1:6. The second layer contains a second ethylene-based polymer. The present disclosure also provides a laminate containing said sealant layer.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: August 17, 2021
    Assignee: Dow Global Technologies LLC
    Inventors: Fengyi Su, Andong Liu, Hongyu Chen, Jianping Pan, Xiao Bing Yun, Thomas Allgeuer, Erqiang Chen, Tipeng Zhao, Guihong Liao
  • Publication number: 20210187812
    Abstract: The coextruded multilayer film has at least two layers, including a sealant layer and a second layer in contact with the sealant layer. The sealant layer contains (A) a first ethylene-based polymer having a density from 0.865 g/cc to 0.930 g/cc and a melt index from 0.5 g/10 min to 25 g/10 min; (B) an unsaturated primary fatty acid amide having a melting point of 100° C. or less; and (C) a saturated primary fatty acid amide having a melting point greater than 100° C. The unsaturated primary fatty acid amide and the saturated primary fatty acid amide have a weight ratio of from 3:1 to 1:6. The second layer contains a second ethylene-based polymer. The present disclosure also provides a laminate containing said sealant layer.
    Type: Application
    Filed: June 9, 2017
    Publication date: June 24, 2021
    Inventors: Fengyi Su, Andong Liu, Hongyu Chen, Jianping Pan, Xiao Bing Yun, Thomas Allgeuer, Erqiang Chen, Tipeng Zhao, Guihong Liao
  • Patent number: 11017958
    Abstract: Disclosed are methods for fabricating supercapacitors (SCs) via vapor printing, specifically oxidative chemical vapor deposition (oCVD). Also disclosed are methods of using the supercapacitors, in particular for energy storage devices and photovoltaics.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: May 25, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Andong Liu, Karen K. Gleason, Peter Kovacik
  • Publication number: 20210115243
    Abstract: The disclosure relates to a tie resin formulation for use as a tie layer in a multilayer structure. The resin includes a first polyolefin grafted with an ethylenically unsaturated carboxylic acid, an ethylenically unsaturated acid derivative or a combination thereof, and having a density of 0.857 to 0.885 g/cm3, and 0.001 to 0.20 weight percent (wt. %) of a catalyst comprising at least one Lewis acid, where the resin includes the catalyst and up to 99.999 wt. % of the first polyolefin, where the wt. % is based on a total weight of the resin.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 22, 2021
    Applicant: Dow Global Technologies LLC
    Inventors: Yong Zheng, Santosh S. Bawiskar, Brian W. Walther, Michael B. Biscoglio, Andong Liu
  • Publication number: 20210108054
    Abstract: Provided is a polymer blend that can be used in films, packages, and fibers. In one aspect, a polymer blend comprises an ethylene-based polymer, and one or more compounds of formula (I), wherein n is 6 to 24.
    Type: Application
    Filed: March 15, 2018
    Publication date: April 15, 2021
    Inventors: Andong Liu, Fengyi Su, Hongyu Chen, Jianping Pan, Xiaobing Yun, Thomas Allgeuer, Di Xu, Yuguo Ma
  • Publication number: 20210078315
    Abstract: Provided is a coextruded multilayer film. The coextruded multilayer film has at least two layers, including a sealant layer and a second layer in contact with the sealant layer. The sealant layer contains (A) a first ethylene-based polymer having a density from 0.865 g/cc to 0.930 g/cc and a melt index from 0.5 g/10 min to 25 g/10 min; (B) an unsaturated primary fatty acid amide having a melting point of 100° C. or less; and (C) a diprotic fatty acid having a melting point greater than 100° C. and a decomposition temperature greater than 200° C. The second layer contains a second ethylene-based polymer. Also provided is a laminate containing said sealant layer.
    Type: Application
    Filed: June 9, 2017
    Publication date: March 18, 2021
    Inventors: Fengyi Su, Andong Liu, Hongyu Chen, Jianping Pan, Xiao Bing Yun, Thomas Allgeuer, Erqiang Chen, Tipeng Zhao, Guihong Liao
  • Publication number: 20210009795
    Abstract: The disclosure relates to a tie resin formulation with excellent adhesion to polyethylene terephthalate (PET). The resin includes (A) an ethylene acrylate copolymer formed from ethylene and alkyl acrylate, where the ethylene acrylate copolymer has an acrylate content of 10 to 30 weight percent and an ethylene content of 90 to 70 weight percent based on the total weight of the ethylene acrylate copolymer and the acrylate content and (B) a transesterification catalyst; where the resin includes: 30 to 99.999 weight percent of the ethylene acrylate copolymer based on the total weight of the resin; 0.001 to 10 weight percent of the transesterification catalyst based on the total weight of the resin; and (C) 0 to 69.999 of a non-polar polyolefin based on the total weight of the resin.
    Type: Application
    Filed: March 29, 2018
    Publication date: January 14, 2021
    Applicant: Dow Global Technologies LLC
    Inventors: Andong Liu, Yunlong Guo, Yong Zheng, Hongyu Chen, Brian Walther, Yi Zhang