Abstract: A variable optical attenuator (VOA) may include an input collimator with an input fiber connected on one side and an output collimator with an output fiber connected on one side, where the collimators are on a same surface of a VOA enclosure. A retroreflector may receive a light beam from the input collimator and reflect the light beam to the output collimator. The VOA may include an attenuation element positioned between the input collimator and the retroreflector and/or another attenuation element positioned between the retroreflector and the output collimator to provide variable attenuation to the light beam. The attenuation elements may be moved to set an attenuation level by one or more adjustment elements such as a miniature motor. The attenuation element may include a gradient index (GRIN) element, a polarizer, a neutral density filter, or a wavelength tunable filter.

Abstract: The present invention relates to an electromechanical battery comprising a single pole-pair Halbach array of permanent magnets incorporated into an annular flywheel, which together comprise a rotor assembly, a means for levitating the rotor assembly using a “double-lift” attractive magnetic levitator under active control, and a means for actively stabilizing the spinning rotor assembly by interaction with the fringe fields of the Halbach array.

Abstract: The present invention relates to an electromechanical battery comprising a single pole-pair Halbach array of permanent magnets incorporated into an annular flywheel, which together comprise a rotor assembly, a means for levitating the rotor assembly using a “double-lift” attractive magnetic levitator under active control, and a means for actively stabilizing the spinning rotor assembly by interaction with the fringe fields of the Halbach array.

Abstract: A LED light fixture includes an LED assembly that emits light when energized through an electrical path. An inner optic is positioned to receive the light. The inner optic comprises a lens that emits the light from the inner optic with a wide beam angle. A reflector is positioned to receive the light emitted from the inner optic. An inner reflector is positioned to asymmetrically reflect the light from the inner optic relative to the reflector.

Abstract: Microdevices are disclosed to efficiently, accurately, and rapidly isolate and enumerate rare cells, such as circulating tumor cells, from liquids such as whole blood. The system employs multiple parallel meandering channels having a width on the order of 1-2 cell diameters. The microdevices can be produced at low-cost, may readily be automated, and in many instances may be used without pre-processing of the sample. They may be used to isolate and enumerate rare cells, including for example the detection and diagnosis of cancers, cancer staging, or evaluating the effectiveness of a therapeutic intervention, or detecting pathogenic bacteria. The device may optionally be used to nondestructively capture and later to release target cells.

Abstract: Microdevices are disclosed to efficiently, accurately, and rapidly isolate and enumerate rare cells, such as circulating tumor cells, from liquids such as whole blood. The system employs multiple parallel meandering channels having a width on the order of 1-2 cell diameters. The microdevices can be produced at low-cost, may readily be automated, and in many instances may be used without pre-processing of the sample. They may be used to isolate and enumerate rare cells, including for example the detection and diagnosis of cancers, cancer staging, or evaluating the effectiveness of a therapeutic intervention, or detecting pathogenic bacteria. The device may optionally be used to nondestructively capture and later to release target cells.

Abstract: Systems and methods are provided herein for multi-pass duplicate identification using sorted neighborhoods. Data comprising a plurality of data records is received. Neighborhood records are generated by merging the plurality of data records with reference records stored in a remote data store. A resource identification field is assigned to each reference record. A pair distance, for each pair of neighborhood records having different resource identification fields, is determined by calculating a standard deviation of distances between each attribute of the pair scaled by a filled pairs quote value. Possible duplicate records are identified by evaluating each pair distance against a threshold, each possible duplicate having grouped attributes. Final duplicate records are identified by matching each group to a key.

Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.

Abstract: A LED light fixture includes an LED assembly that emits light when energized through an electrical path. An inner optic is positioned to receive the light. The inner optic comprises a lens that emits the light from the inner optic with a wide beam angle. A reflector is positioned to receive the light emitted from the inner optic. An inner reflector is positioned to asymmetrically reflect the light from the inner optic relative to the reflector.

Abstract: Microdevices are disclosed to efficiently, accurately, and rapidly isolate and enumerate rare cells, such as circulating tumor cells, from liquids such as whole blood, The system employs multiple parallel meandering channels having a width on the order of 1-2 cell diameters. The microdevices can be produced at low-cost, may readily be automated, and in many instances may be used without pre-processing of the sample. They may he used to isolate and enumerate rare cells, including for example the detection and diagnosis of cancers, cancer staging, or evaluating the effectiveness of a therapeutic intervention, or detecting pathogenic bacteria, The device may optionally he used to nondestructively capture and later to release target cells.

Abstract: Systems and methods are provided herein for multi-pass duplicate identification using sorted neighborhoods. Data comprising a plurality of data records is received. Neighborhood records are generated by merging the plurality of data records with reference records stored in a remote data store. A resource identification field is assigned to each reference record. A pair distance, for each pair of neighborhood records having different resource identification fields, is determined by calculating a standard deviation of distances between each attribute of the pair scaled by a filled pairs quote value. Possible duplicate records are identified by evaluating each pair distance against a threshold, each possible duplicate having grouped attributes. Final duplicate records are identified by matching each group to a key.

Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.

Abstract: A synthetic skin tissue is served by at least one synthetic blood vessel and includes a physiologically representative population of cells including fibroblasts and keratinocytes, wherein some keratinocytes are in a differentiated state.

Abstract: Synthetic human blood vessels can be constructed using human brain derived endothelial cells and incorporated into a tissue model that contains astrocytes and other neurons and microglia. Multi-cell type microvessels incorporate cell types such as astrocytes and pericytes in order to construct a highly representative blood-brain barrier in vitro model with a functional lumen containing brain-derived microvascular endothelial cells and a polymer wall containing human astrocytes and/or pericytes.

Abstract: A method of direct-write manufacturing (3D printing) includes a simple to manufacture printhead configured to create sheathed flow. The method is operable at room temperature and suitable for use with sensitive materials.

Abstract: A perfusable, microtube-based flow system for microdevice models of human tissues and organs includes a microfluidic chip with a network of microtubes passing through at least one common chamber space suitable to hold cells of an appropriate organ and/or a biocompatible support matrix. The microtube model network can be used to create model tissues and organs for study and research.

Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.

Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.

Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.

Abstract: Various embodiments of systems and methods for representing data fields of a data table are described herein. In one aspect, the method includes determining at least one data field of a data table. Data related to the determined at least one data field is read. A graphical representation of the data related to the determined at least one data field is generated. The generated graphical representation is displayed along with the data table. A user selection of a subset of data displayed on the graphical representation is received. A subset of the data table is displayed based upon the selected subset of data.