Patents by Inventor André GÖRGENS

André GÖRGENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USES OF EXTRACELLULAR VESICLE COMPRISING A FUSION PROTEIN HAVING FC BINDING CAPACITY
    Publication number: 20230181757
    Abstract: The present invention pertains to engineered extracellular vesicles (EVs) for use in a variety of research, diagnostic, imaging and therapeutic applications. The EVs are engineered to enable incorporation and surface display of various proteins of interest, which may be exogenous and/or endogenous in nature. The coating of EVs is achieved through inventive protein engineering of EV polypeptides, and the present invention thus relates to methods for coating of EVs, EVs per se, as well kits, detection methods, diagnostic applications, imaging and delivery methods based on said engineered EVs.
    Type: Application
    Filed: July 21, 2017
    Publication date: June 15, 2023
    Applicants: Evox Therapeutics Ltd, Evox Therapeutics Ltd
    Inventors: André GÖRGENS, Dhanu GUPTA, Oscar WIKLANDER
  • EXTRACELLULAR VESICLE COMPRISING A FUSION PROTEIN HAVING FC BINDING CAPACITY
    Publication number: 20220098267
    Abstract: The present invention pertains to extracellular vesicle (EV) therapeutics, wherein the EVs are coated with proteins containing Fc domains (such as antibodies) for i.a. targeting and therapeutic applications. The coating of EVs is achieved through inventive protein engineering of EV polypeptides. The present invention thus relates to methods for coating of EVs, EVs per se, as well as pharmaceutical compositions and medical applications of such EVs coated with Fc containing proteins.
    Type: Application
    Filed: December 15, 2021
    Publication date: March 31, 2022
    Inventors: Oscar WIKLANDER, André GÖRGENS, Dhanu GUPTA
  • Extracellular vesicle comprising a fusion protein having Fc binding capacity
    Patent number: 11236143
    Abstract: The present invention pertains to extracellular vesicle (EV) therapeutics, wherein the EVs are coated with proteins containing Fc domains (such as antibodies) for i.a. targeting and therapeutic applications. The coating of EVs is achieved through inventive protein engineering of EV polypeptides. The present invention thus relates to methods for coating of EVs, EVs per se, as well as pharmaceutical compositions and medical applications of such EVs coated with Fc containing proteins.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: February 1, 2022
    Assignee: Evox Therapeutics Ltd
    Inventors: Oscar Wiklander, André Görgens, Dhanu Gupta
  • COMPOSITIONS FOR EXTRACELLULAR VESICLE STORAGE AND FORMULATION
    Publication number: 20210069254
    Abstract: The present invention relates to compositions and buffers for storing engineered extracellular vesicles (EVs), such as exosomes, for extended time periods with maintained stability and function. The present invention allows for both optimized long-term storage and for clinical application of the stored EVs.
    Type: Application
    Filed: February 11, 2019
    Publication date: March 11, 2021
    Inventors: André GÖRGENS, Samir EL ANDALOUSSI, Oscar WIKLANDER, Giulia CORSO
  • EXTRACELLULAR VESICLE COMPRISING A FUSION PROTEIN HAVING FC BINDING CAPACITY
    Publication number: 20200109183
    Abstract: The present invention pertains to extracellular vesicle (EV) therapeutics, wherein the EVs are coated with proteins containing Fc domains (such as antibodies) for i.a. targeting and therapeutic applications. The coating of EVs is achieved through inventive protein engineering of EV polypeptides. The present invention thus relates to methods for coating of EVs, EVs per se, as well as pharmaceutical compositions and medical applications of such EVs coated with Fc containing proteins.
    Type: Application
    Filed: July 21, 2017
    Publication date: April 9, 2020
    Applicants: Evox Therapeutics Ltd, Evox Therapeutics Ltd
    Inventors: Oscar WIKLANDER, André GÖRGENS, Dhanu GUPTA