Patents by Inventor André Niestroj

André Niestroj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the treatment of neurological disorders
    Patent number: 7667044
    Abstract: The present invention relates to novel inhibitors of prolyl endopeptidase of formula 1 W—KCONH—X—CON—Y—CO—Z??(1) wherein K, W, X, Y and Z are specified in the description. The compounds are useful for the treatment of diseases such as mild cognitive impairment (MCI), Alzheimer's disease, Down Syndrome, Parkinson disease and Chorea Huntington.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: February 23, 2010
    Assignee: Probiodrug AG
    Inventors: André Niestroj, Ulrich Heiser, Ingo Schulz, Jens-Ulrich Rahfeld, Joachim Baer, Hans-Ulrich Demuth
  • Irreversible cysteine protease inhibitors of legumain
    Patent number: 7279550
    Abstract: Presented are compounds represented by the following general formulas (I) and (II), for inhibiting cysteine protease legumain for modulating associated disease states in subjects
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: October 9, 2007
    Assignee: Probiodrug AG
    Inventors: André Niestroj, Ulrich Heiser, Bernd Gerhartz, Matthias Hoffmann, Hans-Ulrich Demuth