Patents by Inventor Andrés FINZI

Andrés FINZI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS BASED ON HIV GP120 MUTANTS
    Publication number: 20220380414
    Abstract: Compositions and methods based on the use of mutated HIV-1 gp120 polypeptides having amino acid substitutions at positions 61, 105, 108, 375, 474, 475 and 476 are described. These mutated HIV-1 gp120 polypeptides, which make the HIV env protein more amenable to adopt specific conformations when contacted with gp120 ligands, may be useful as vaccines or tools to identify and characterize agents modulating HIV infection.
    Type: Application
    Filed: September 23, 2020
    Publication date: December 1, 2022
    Inventors: Andrés FINZI, Jérémie PRÉVOST, Marzena PAZGIER, Amos B. SMITH, III
  • SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY
    Publication number: 20220363639
    Abstract: Compounds and methods of treating HIV-1 in a human infected with HIV-1 or preventing HIV-1 infection in a human susceptible to infection with HIV-1 are provided. The compounds are of formula (I), (II), and (IA), wherein R1-R7, X, X?, Y, Y?, Z, and n are defined herein, and the methods comprises administering therapeutically effective amounts of these compounds to the human.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 17, 2022
    Inventors: Melissa Carey GRENIER, Amos B. SMITH, III, Andres FINZI, Shilei DING, Jean-Philippe CHAPLEAU