Patents by Inventor André SCHIEFNER

André SCHIEFNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH AFFINITY ANTICALINS DIRECTED AGAINST HUMAN CD98hc
    Publication number: 20220153790
    Abstract: The present invention relates to a cluster of differentiation 98 heavy chain (CD98hc)-specific binding protein, wherein the CD98hc-specific binding protein is a lipocalin 2 (Lcn2)-derived binding protein and binds to CD98hc with a KD of 200 nM or lower.
    Type: Application
    Filed: March 18, 2020
    Publication date: May 19, 2022
    Inventors: Arne SKERRA, Friedrich-Christian DEUSCHLE, André SCHIEFNER, Volker MORATH
  • Recombinant bacterial lipocalin Blc and uses thereof
    Patent number: 9630998
    Abstract: The present inventors have solved the crystal structure of an Escherichia coli bacterial lipocalin polypeptide, which depicts a monomeric protein. Previous crystal structures have been reported, but these appear to he inaccurate, as they predicted, e.g., a dimeric protein. The crystal structure of a bacterial lipocalin provided by the present invention leads to numerous uses. For example, the present invention provides for the design, construction and use of recombinant libraries of diversified bacterial lipocalins resulting from a bacterial lipocalin polypeptide “backbone”.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: April 25, 2017
    Assignee: Technische Universitaet Muenchen
    Inventors: Arne Skerra, Andre Schiefner
  • RECOMBINANT BACTERIAL LIPOCALIN BLC AND USES THEREOF
    Publication number: 20150191512
    Abstract: The present inventors have solved the crystal structure of an Escherichia coli bacterial lipocalin polypeptide, which depicts a monomeric protein. Previous crystal structures have been reported, but these appear to he inaccurate, as they predicted, e.g., a dimeric protein. The crystal structure of a bacterial lipocalin provided by the present invention leads to numerous uses. For example, the present invention provides for the design, construction and use of recombinant libraries of diversified bacterial lipocalins resulting from a bacterial lipocalin polypeptide “backbone”.
    Type: Application
    Filed: February 12, 2015
    Publication date: July 9, 2015
    Applicant: Technische Universitaet Muenchen
    Inventors: Arne SKERRA, Andre Schiefner
  • Recombinant bacterial lipocalin blc and uses thereof
    Patent number: 8987415
    Abstract: The present inventors have solved the crystal structure of an Escherichia coli bacterial lipocalin polypeptide, which depicts a monomeric protein. Previous crystal structures have been reported, but these appear to be inaccurate, as they predicted, e.g., a dimeric protein. The crystal structure of a bacterial lipocalin provided by the present invention leads to numerous uses. For example, the present invention provides for the design, construction and use of recombinant libraries of diversified bacterial lipocalins resulting from a bacterial lipocalin polypeptide “backbone”.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: March 24, 2015
    Assignee: Technische Universitaet Muenchen
    Inventors: Arne Skerra, Andre Schiefner
  • RECOMBINANT BACTERIAL LIPOCALIN BLC AND USES THEREOF
    Publication number: 20130331550
    Abstract: The present inventors have solved the crystal structure of an Escherichia coli bacterial lipocalin polypeptide, which depicts a monomeric protein. Previous crystal structures have been reported, but these appear to be inaccurate, as they predicted, e.g., a dimeric protein. The crystal structure of a bacterial lipocalin provided by the present invention leads to numerous uses. For example, the present invention provides for the design, construction and use of recombinant libraries of diversified bacterial lipocalins resulting from a bacterial lipocalin polypeptide “backbone”.
    Type: Application
    Filed: September 7, 2011
    Publication date: December 12, 2013
    Inventors: Arne Skerra, Andre Schiefner