Patents by Inventor Andras Berta

Andras Berta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS AND KIT FOR MEASURING THE CONDITION OF THE FIBRINOLITIC SYSTEM
    Publication number: 20100068745
    Abstract: The invention relates to an assay and a kit for the determination of the status of the fibrinolytic system. In particular the invention relates to a method for the determination of the status of the fibrinolytic system from tear fluid samples.
    Type: Application
    Filed: May 29, 2009
    Publication date: March 18, 2010
    Inventors: Andras Berta, Adrienne Csutak, Tamas Sperka, Jozsef Tozser
  • Plasminogen activator to prevent corneal and subepithelial haze after laser vision correction surgery
    Patent number: 7179461
    Abstract: The present invention is directed to a method to prevent or reduce postoperative corneal subepithelial haze after excimer laser photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK) surgery. According to the method, a therapeutically effective amount of one or more plasminogen activators, most preferably urokinase (uPA), is administered topically to the surface of the affected eye at levels between 0.1 and 2,500 IU/ml, about eight to twelve times on the day of surgery, and four to eight times per day for about the next six to twelve days thereafter. The most preferred therapeutic amount is from about 0.1–1 IU uPA/ml, and also 1–10 IU/ml. Plasminogen activators that can be used in the inventions include urokinase, prourokinase, streptokinase and mutants thereof. The invention also covers topical ophthalmic compositions that include one or more plasminogen activators, most preferably uPA, to prevent or reduce postoperative corneal subepithelial haze.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: February 20, 2007
    Assignee: The Johns Hopkins University
    Inventors: David M. Silver, Adrienne Csutak, Andras Berta, Jozsef Tozser
  • Plasminogen activator to prevent corneal and subepithelial haze after laser vision correction surgery
    Publication number: 20040001821
    Abstract: The present invention is directed to a method to prevent or reduce postoperative corneal subepithelial haze after excimer laser photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK) surgery. According to the method, a therapeutically effective amount of one or more plasminogen activators, most preferably urokinase (uPA), is administered topically to the surface of the affected eye at levels between 0.1 and 2,500 IU/ml, about eight to twelve times on the day of surgery, and four to eight times per day for about the next six to twelve days thereafter. The most preferred therapeutic amount is from about 0.1-1 IU uPA/ml, and also 1-10 IU/ml. Plasminogen activators that can be used in the inventions include urokinase, prourokinase, tissue plasminogen activator, streptokinase and mutants thereof. The invention also covers topical ophthalmic compositions that include one or more plasminogen activators, most preferably uPA, to prevent or reduce postoperative corneal subepithelial haze.
    Type: Application
    Filed: April 9, 2003
    Publication date: January 1, 2004
    Inventors: David M. Silver, Adrienne Csutak, Andras Berta, Jozsef Tozser