Patents by Inventor Andras Dietz

Andras Dietz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing 1-[/2S/-methyl -3-mercapto-propionyl]-pyrrolidine-/2S/-carboxylic acid
    Patent number: 5276207
    Abstract: The invention relates to a novel process for preparing 1-[/2S/-methyl-3-mercaptopropionyl]-pyrrolidine-/2S/-carboxylic acid of the formula I ##STR1## in which 1-[/2S/-methyl-3-thiocyanatopropionyl]-pyrrolidine-/2S/-carboxylic acid of the formula II ##STR2## is dissolved in an aqueous mineral acid, the solution obtained is diluted with water and the 1-[/2S/-methyl-3-carbamoylthiopropionyl]-pyrrolidine-/2S/-carboxylic acid of the formula III ##STR3## that forms is hydrolized with an aqueous solution of a base.
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: January 4, 1994
    Assignee: Egis Gyogyszergyar Rt.
    Inventors: Geza Schneider, Gabor Blasko, Agnes Kovacs nee Palotai, Gabriella rmos nee Lassu, Ilma Dinnyes nee Nagy, Ivan Beck, Elemer Jakfalvi, Andras Dietz
  • Process for preparing 1-(2S)-3-mercapto-methyl-1-oxopropyl)-L-proline
    Patent number: 5202443
    Abstract: The invention relates to a novel process for preparing 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-L-proline (captopril) of formula (I). ##STR1## which comprises hydrogenolysing 1-[(2S)-2-methyl-1-oxo-3-rhodanidopropyl]-L-proline of formula (II) ##STR2## in an inert solvent, in the presence of a catalyst, at a temperature of 50.degree. to 120.degree. C. under a pressure of 10.sup.5 to 10.sup.7 Pa.The above compound of formula (II) is new and can be prepared by acylating L-proline with a reactive acylating derivative of (2S)-2-methyl-3-rhodanido-propionic acid of formula (III).
    Type: Grant
    Filed: September 20, 1991
    Date of Patent: April 13, 1993
    Assignee: EGIS Gyogyszergyar
    Inventors: Geza Schneider, Gabor Blasko, Agnes Kovacs nee Palotai, Gabriella rmos nee Lassu, Judit Kun, Ilma Dinnyes nee Nagy, Ivan Beck, Elemer Jakflavi, Andras Dietz
  • Pharmaceutical compositions
    Patent number: 4883798
    Abstract: The compounds of the general Formula I ##STR1## (wherein R.sup.1 and R.sup.2 may be the same or different and each stands for hydrogen, hydroxy, C.sub.1-6 alkoxy, C.sub.1-6 alkoxy-C.sub.1-6 alkoxy, C.sub.2-6 alkenyloxy or phenyl-(C.sub.1-3 alkoxy), or R.sup.1 and R.sup.2 together form C.sub.1-2 alkylenedioxy; with the proviso that at least one of symbols R.sup.1 and R.sup.2 is other than hydrogen and with the further proviso that R.sup.1 and R.sup.2 can not represent 3,4-dimethoxy substitution) andtheir pharmaceutically acceptable acid addition salts exhibit useful analgesic, antipyretic, anti-inflammatory, anti-anginal and antioxidant effect.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: November 28, 1989
    Assignee: EGIS Gyogyszergyar
    Inventors: Lujza Petocz, Istvan Simonyi, Ivan Beck, Gabor Gigler, Marton Fekete, Eniko Szirt nee Kiszelly, Attila Mandi, Frigyes Gorgenyi, Andras Dietz, Elemer Jakfalvi, Katalin Zukovics nee Sumeg, Klara Gado, Maria Hegedus
  • Pharmaceutical composition
    Patent number: 4873249
    Abstract: The invention relates to pharmaceutical compositions having analgesic and/or anti-inflammatory effect comprising as active ingredient 2,4-diamino-5-(3,4-dimethoxy-benzyl)-pyrimidine or a pharmaceutically acceptable acid addition salt thereof.The pharmaceutical compositions of the present invention exhibit the desired analgesic and anti-inflammatory effect without causing undesired ulcerogenic side-effects.
    Type: Grant
    Filed: February 20, 1987
    Date of Patent: October 10, 1989
    Assignee: EGIS Gyogyszergyar
    Inventors: Lujza Petocz, Istvan Simonyi, Ivan Beck, Gabor Gigler, Marton Fekete, Eniko Kiszelly, Attila Mandi, Frigyes Gorgenyi, Andras Dietz, Katalin Sumeg nee Zukovics, Elemer Jakfalvi