Patents by Inventor Andras Fiser

Andras Fiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240270812
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Application
    Filed: January 5, 2024
    Publication date: August 15, 2024
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Patent number: 11435355
    Abstract: A system and a method for identifying a cognate ligand molecules for known proteins.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: September 6, 2022
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Andras Fiser, Enghui Yap
  • Publication number: 20220047729
    Abstract: Disclosed are human Programmed Cell Death-1 (PD-1) receptor mutants having selectivity for PD-L1 compared to PD-L2, methods of obtaining the mutants, and uses of the mutants for treatment and imaging.
    Type: Application
    Filed: September 18, 2019
    Publication date: February 17, 2022
    Inventors: Andras Fiser, Rojan Shrestha, Steven C. Almo, Sarah, C. Garrett
  • Publication number: 20210388052
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Application
    Filed: January 4, 2021
    Publication date: December 16, 2021
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Patent number: 10882893
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: January 5, 2021
    Assignee: Albert Einstein College of Medicine
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Publication number: 20190369097
    Abstract: A system and a method for identifying a cognate ligand molecules for known proteins.
    Type: Application
    Filed: January 4, 2017
    Publication date: December 5, 2019
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Andras Fiser, Enghui Yap
  • Publication number: 20190263886
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Application
    Filed: March 13, 2019
    Publication date: August 29, 2019
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Patent number: 10280208
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 7, 2019
    Assignee: Albert Einstein College of Medicine
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Publication number: 20170174742
    Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.
    Type: Application
    Filed: April 24, 2015
    Publication date: June 22, 2017
    Inventors: Xingxing Zang, Jordan M. Chinai, Murali Janakiram, Steven C. Almo, Andras Fiser
  • Publication number: 20120078530
    Abstract: The present invention provides a method of determining related proteins, the method comprising obtaining sequences of interest, wherein the sequences are amino acid sequences for proteins or nucleotide sequences encoding proteins; comparing segments of each sequence of interest with a database of amino acid or nucleotide sequences; generating a profile for each sequence of interest comprising a list of all sequences from the database of sequences that have segments corresponding to the segments of each sequence of interest; and comparing the database sequences appearing in the profile of each sequence of interest to the database sequences appearing in the profile of every other sequence of interest, wherein similar profiles indicate that the sequences of interest correspond to related proteins while dissimilar profiles indicate that the sequences of interest do not correspond to related proteins, wherein profiles are similar if there is at least a 30% overlap between the database sequences appearing in the pr
    Type: Application
    Filed: April 12, 2011
    Publication date: March 29, 2012
    Inventors: Steven C. Almo, Andras Fiser, Rotem Rubinstein