Abstract: The present invention relates to a vaccine composed of at least one immune stimulant and radiofrequency waves using capacitive coupling and to a method, especially an in-situ and in vivo vaccination method for treatment of primary cancer and its metastases even in disseminated cell-states, which cannot be detected by presently available imaging methods or for prevention of relapse of the cancer disease, and especially for enabling and supporting the patient's own immune system to recognize and kill the cancer cells and to build up a memory to prevent relapse of a cancer disease.

Abstract: The present invention relates to a radiofrequency (RF) hyperthermia device for personalized treatment and diagnosis using capacitive coupling and without dipole antenna comprising a radiofrequency source, an amplifier, a sensor and a modulation signal input/generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal input/generator using the phase information generated by homeostasis of the target to generate a modulated source signal, the modulated source signal is amplified by the amplifier and directed to a target, and the sensor detects the phase information generated by homeostasis of the target to provide a feedback signal, wherein the feedback signal modulates the source signal to generate a personalized modulated signal. This radiofrequency (RF) hyperthermia device is designed for personalized treatment and diagnosis of a target such as a patient or a malignant or tumorous area within a patient.

Abstract: The present disclosure relates to a portable radiofrequency (RF) hyperthermia device having flexible applicator treatment electrodes for electric field capacitive coupled energy transfer, the device being useful for increasing the delivery of a systemically delivered drug at a localized target site. The portable RF device is suitable for use by a patient in their own home and the flexible applicator is a flexible, porous, light and easy to manipulate treatment electrode. The inventive device requires no specialist operator to ensure correct usage.

Abstract: The present invention is related to a radiofrequency electrode (RF electrode) for the use in hyperthermia that can be fitted to the shape of a target to be treated (e.g. a patient) and that is also able to reversibly retain the shape it has been fitted to. Thereby, a reliable and close contact between the target to be treated (e.g. a patient) and the inventive RF electrode is established that enables an efficient and safe energy transfer to the target to be treated during a hyperthermia treatment of various medical conditions or for cosmetic purposes.

Abstract: The present invention relates to a flexible electric field capacitive coupled energy transfer means formed from a conductive metal coated flexible material or flexible metallic net. The improved energy transfer means is flexible, porous, light and easy to manipulate treatment electrode and is used in non-invasive electrical field hyperthermia.

Abstract: The present invention relates to a radiofrequency (RF) hyperthermia device for capacitive coupling comprising a radiofrequency source, an amplifier, a sensor, a feedback amplifier and a modulation signal generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal generator, amplified by the amplifier and directed to a target, the sensor receives a feed back signal from the target that is directed to the feed back amplifier, wherein the feedback signal is amplified by the feedback amplifier and modulates the source signal to generate a target modified signal. This radiofrequency (RF) hyperthermia device is designed for increasing the selectivity of the hyperthermia treatment.

Abstract: The present invention relates to a vaccine composed of at least one immune stimulant and radiofrequency waves using capacitive coupling and to a method, especially an in-situ and in vivo vaccination method for treatment of primary cancer and its metastases even in disseminated cell-states, which cannot be detected by presently available imaging methods or for prevention of relapse of the cancer disease, and especially for enabling and supporting the patient's own immune system to recognize and kill the cancer cells and to build up a memory to prevent relapse of a cancer disease.

Abstract: The present invention relates to a radiofrequency (RF) hyperthermia device for personalized treatment and diagnosis using capacitive coupling and without dipole antenna comprising a radiofrequency source, an amplifier, a sensor and a modulation signal input/generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal input/generator using the phase information generated by homeostasis of the target to generate a modulated source signal, the modulated source signal is amplified by the amplifier and directed to a target, and the sensor detects the phase information generated by homeostasis of the target to provide a feedback signal, wherein the feedback signal modulates the source signal to generate a personalized modulated signal. This radiofrequency (RF) hyperthermia device is designed for personalized treatment and diagnosis of a target such as a patient or a malignant or tumorous area within a patient.

Abstract: The present invention relates to a radiofrequency (RF) hyperthermia device for capacitive coupling comprising a radiofrequency source, an amplifier, a sensor, a feedback amplifier and a modulation signal generator, wherein the radiofrequency source produces a source signal which is modulated by the modulation signal generator, amplified by the amplifier and directed to a target, the sensor receives a feed back signal from the target that is directed to the feed back amplifier, wherein the feedback signal is amplified by the feedback amplifier and modulates the source signal to generate a target modified signal. This radiofrequency (RF) hyperthermia device is designed for increasing the selectivity of the hyperthermia treatment.

Abstract: The present disclosure relates to a portable radiofrequency (RF) hyperthermia device having flexible applicator treatment electrodes for electric field capacitive coupled energy transfer, the device being useful for increasing the delivery of a systemically delivered drug at a localised target site. The portable RF device is suitable for use by a patient in their own home and the flexible applicator is a flexible, porous, light and easy to manipulate treatment electrode. The inventive device requires no specialist operator to ensure correct usage.

Abstract: The present invention relates to a flexible electric field capacitive coupled energy transfer means formed from a conductive metal coated flexible material or flexible metallic net. The improved energy transfer means is flexible, porous, light and easy to manipulate treatment electrode and is used in non-invasive electrical field hyperthermia.

Abstract: A drain installation apparatus for installing a drain assembly in a drain hole of a plumbing fixture. The drain installation apparatus includes a bridging member for bridging over the drain hole. A support member extends toward the drain hole when the bridging member is positioned over the drain hole. A holding member engages a top of the drain assembly. A handle member is mounted on the support member for being gripped by a hand of a user to rotate the support member. An attachment member is mounted on the bridging member for releasably mounting on an inner surface of the plumbing fixture adjacent to the drain hole. A cup member engages an upper fastener of the drain assembly. A lower handle member is mounted on the cup member for gripping by the hand of the user to produce rotation of the cup member. An engaging member engages a lower fastener of the drain assembly.

Abstract: A pharmaceutical composition that is suitable for inhalation is disclosed, thus ensuring an effective treatment of the lungs. For this purpose, an aerosol composition is believed to be suited. The aerosol preparation comprises a stabilized suspension of sodium cromoglycate from which the active substance is favorably absorbed in the lungs after inhalation. In the aerosol preparation, 1 to 4% by mass of sodium cromoglycate is suspended in a mixture of propellants comprising 0.3 to 2.0% by mass of a dispersing agent consisting of oleyl oleate.

Abstract: A pseudo double circuit battery and associated circuit for incorporating the battery into conventional vehicle starting and charging systems. The battery is made up of a series of conventional cells and includes at least one cell which has an additional positive or negative terminal to form an auxiliary circuit terminal. During a starting or cranking phase of operation, the main circuit of the battery is isolated from the auxiliary circuit and is connected to energize the heavy load circuits of the automobile. The auxiliary terminal is connected so as to provide stable power to light load circuits, for example the ignition circuit. During running of the automobile the main and auxiliary terminals are connected.

Abstract: A process is disclosed for the preparation of compounds of the Formula IR--X--R.sup.1 (I)wherein X is thio, dithio or carbonyl and R and R.sup.1 are defined hereinbelow which comprises reducing a compound of the Formula IIR--A (II)wherein A is chlorosulfonyl or a group of the Formula ##STR1## with a sulfur compound comprising sulfur which is of the (+)4 oxidation degree and is converted into the (+)6 oxidation degree during the process or with a sulfur compound which is decomposed in acidic medium to a compound of the latter oxidation degree in the presence of a catalytic amount but not more than 0.5 mole--related to 1 mole of the starting material of the Formula II--of elemental iodine or a compound capable of delivering hydrogen iodide in acidic medium or a compound which can be reduced to hydrogen iodide in acidic medium with the sulfur compound used.