Patents by Inventor Andre A. Kiryanov

Andre A. Kiryanov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polo-like kinase inhibitors
    Patent number: 8318727
    Abstract: Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: November 27, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Sheldon X Cao, Victoria Feher, Takashi Ichikawa, Benjamin Jones, Stephen W. Kaldor, Andre A. Kiryanov, Yan Liu, Chrisopher McBride, Srinivasa Ready Natala, Zhe Nie, Jeffrey A. Stafford, Betty Lam
  • POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS
    Publication number: 20120129868
    Abstract: Compounds of the following formula are provided for use with PARP: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits, and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds.
    Type: Application
    Filed: July 29, 2010
    Publication date: May 24, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Jason W. Brown, Anthony R. Gangloff, Andre A. Kiryanov
  • Poly (ADP-Ribose) Polymerase (PARP) Inhibitors
    Publication number: 20120122835
    Abstract: Disclosed are compounds of the following formula: in which R1, R2, R3, R4, R5, R6, R7, X, and t are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
    Type: Application
    Filed: January 18, 2012
    Publication date: May 17, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Anthony R. Gangloff, Andrew John Jennings, Benjamin Jones, Andre A. Kiryanov
  • Renin inhibitors
    Patent number: 8138168
    Abstract: The invention relates to compounds having the formulae: wherein the variables are as defined herein. The invention further relates to methods of making and using these compounds, and pharmaceutical compositions, kits and articles of manufacture comprise the compounds.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: March 20, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Benjamin Jones, Stephen W. Kaldor, Walter Keung, Andre A. Kiryanov, Zhe Li, Jeffrey A. Stafford, John Tyhonas, Craig Behnke
  • Substituted 7,8,9,10-tetrahydro-5H-dipyrido[1,2-a:3?,2?-e]pyrazin-6(6aH)-ones
    Patent number: 8124606
    Abstract: Disclosed are compounds of the following formula: in which R1, R2, R5, R6, R7, R11, X, and m are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: February 28, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Anthony R. Gangloff, Andrew John Jennings, Benjamin Jones, Andre A. Kiryanov
  • POLO-LIKE KINASE INHIBITORS
    Publication number: 20110201818
    Abstract: Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: September 24, 2008
    Publication date: August 18, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Takashi Ichikawa, Benjamin Jones, Andre A. Kiryanov, Christopher McBride, Srinivasa Reddy Natala, Zhe Nie, Sheldon X. Cao, Betty Lam, Victoria Feher, Stephen W. Kaldor, Yan Liu, Jeffrey A Stafford
  • Poly (ADP-Ribose) Polymerase (PARP) INHIBITORS
    Publication number: 20110158989
    Abstract: Disclosed are compounds of the following formula: in which R1, R2, R3, R4, R5, R6, R7, X, and t are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 30, 2011
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Anthony R. Gangloff, Andrew John Jennings, Benjamin Jones, Andre A. Kiryanov
  • Substituted 6a,7,8,9-tetrahydropyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-ones
    Patent number: 7928105
    Abstract: Disclosed are compounds of the following formula: in which R1, R2, R5, R6, R7, R31, u, and X are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: April 19, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Anthony R. Gangloff, Andrew John Jennings, Benjamin Jones, Andre A. Kiryanov
  • POLO-LIKE KINASE INHIBITORS
    Publication number: 20110082111
    Abstract: Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: December 7, 2010
    Publication date: April 7, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Sheldon X. Cao, Victoria Feher, Takashi Ichikawa, Benjamin Jones, Stephen W. KALDOR, Andre A. KIRYANOV, Betty Lam, Yan Liu, Christopher McBride, Srinivasa Reddy Natala, Zhe Nie, Jeffrey A. Stafford
  • RENIN INHIBITORS
    Publication number: 20100210635
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with Renin that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: March 23, 2007
    Publication date: August 19, 2010
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Benjamin Jones, Andre A. Kiryanov, Stephen W. Kaldor
  • Poly (ADP-Ribose) Polymerase (PARP) Inhibitors
    Publication number: 20100190763
    Abstract: Disclosed are compounds of the following formula: in which R1, R2, R3, R4, R5, R6, R7, X, and t are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
    Type: Application
    Filed: January 21, 2010
    Publication date: July 29, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Anthony R. Gangloff, Andrew John Jennings, Benjamin Jones, Andre A. Kiryanov
  • Hydroxysteroid dehydrogenase inhibitors
    Patent number: 7759339
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with hydroxysteroid dehydrogenases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: July 20, 2010
    Assignee: Takeda San Diego, Inc.
    Inventors: Kathleen Aertgeerts, Nancy K. Brennan, Sheldon X. Cao, Edcon Chang, Andre A. Kiryanov, Yan Liu
  • POLO-LIKE KINASE INHIBITORS
    Publication number: 20100075973
    Abstract: The present invention provides PLK inhibitors of the formula wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using the compounds.
    Type: Application
    Filed: August 20, 2009
    Publication date: March 25, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Sheldon X. Cao, Takashi Ichikawa, Andre A. Kiryanov, Christopher McBride, Srinivasa Reddy Natala, Stephen W. Kaldor, Jeffrey A. Stafford
  • POLO-LIKE KINASE INHIBITORS
    Publication number: 20090291938
    Abstract: Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: November 19, 2008
    Publication date: November 26, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Sheldon X. Cao, Victoria Feher, Takashi Ichikawa, Benjamin Jones, Stephen W. Kaldor, Andre A. Kiryanov, Betty Lam, Yan Liu, Christopher McBride, Srinivasa Reddy Natala, Zhe Nie, Jeffrey A. Stafford
  • POLO-LIKE KINASE INHIBITORS
    Publication number: 20090281092
    Abstract: Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
    Type: Application
    Filed: September 24, 2008
    Publication date: November 12, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Sheldon X. Cao, Victoria Feher, Takashi Ichikawa, Benjamin Jones, Stephen W. Kaldor, Andre A. Kiryanov, Betty Lam, Yan Liu, Christopher McBride, Srinivasa Reddy Natala, Zhe Nie, Jeffrey A. Stafford
  • Hydroxysteroid dehydrogenase inhibitors
    Publication number: 20060223829
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with hydroxysteroid dehydrogenases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
    Type: Application
    Filed: March 28, 2006
    Publication date: October 5, 2006
    Inventors: Kathleen Aertgeerts, Nancy Brennan, Sheldon Cao, Edcon Chang, Andre Kiryanov, Yan Liu