Patents by Inventor Andre A. Pavia

Andre A. Pavia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphiphilic fluorine derivatives with telomeric structures; preparation procedure and biomedical applications
    Patent number: 6359006
    Abstract: New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: wherein RF is a fluorinated radical, X is a linear or branched alkylene, R1 is H or CH3, R2 is a radical having at least one OH group, R3 is a radical derived from an amino acid or a peptide, 1≦n≦50 and 0≦m≦200 with 0.2≦n/n+m≦1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: March 19, 2002
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif
  • AMPHIPHILIC FLUORINE DERIVATIVES WITH TELOMERIC STRUCTURES; PREPARATION PROCEDURE AND BIOMEDICAL APPLICATIONS
    Publication number: 20020019442
    Abstract: New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: 1
    Type: Application
    Filed: June 28, 1999
    Publication date: February 14, 2002
    Inventors: ANDRE A. PAVIA, BERNARD PUCCI, JEAN G. RIESS, LEILA ZARIF
  • Amphiphilic fluorine derivatives with telomeric structures
    Patent number: 5703126
    Abstract: Fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1.These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 30, 1997
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif
  • Amphiphilic compounds derived from amino acids or peptides, their methods of synthesis and their application as drug delivery systems
    Patent number: 5650393
    Abstract: Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 22, 1997
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif, Camille Guedj
  • Amphiphilic compounds derived from amino acids or peptides, their methods of synthesis and their application as drug delivery systems
    Patent number: 5637564
    Abstract: Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 10, 1997
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif, Camille Guedj
  • Amphiphilic fluorine derivatives with telomeric structures
    Patent number: 5527962
    Abstract: New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1.These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
    Type: Grant
    Filed: May 5, 1994
    Date of Patent: June 18, 1996
    Assignee: Alliance Pharmaceutical Corp.
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif
  • Amphiphilic compounds derived from amino acids or peptides, their methods of synthesis and their application as drug delivery systems
    Patent number: 5446023
    Abstract: Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: August 29, 1995
    Assignee: Alliance Pharmaceutical Corporation
    Inventors: Andre A. Pavia, Bernard Pucci, Jean G. Riess, Leila Zarif, Camille Guedj