Abstract: Embodiments of the present disclosure include an aseptic joint assembly for use in minimally invasive surgical imaging systems implementing a positioning arm. According to some aspects, the aseptic joint assembly includes at least one adaptor having a locking mechanism used to removably attach the adaptor onto an end of the positioning arm of the surgical visualization positioning system and directly or indirectly support at least one or both a display and an imaging device of the visualization system. In some embodiments, controlled rotation about one or more axis can be provided for moving the imaging device via an end effector and in relation to a surgical site. According to additional aspects, a surgical drape can be bonded to at least a portion of an adaptor and is configured to cover at least a portion a length of the positioning arm of the surgical visualization system.