Patents by Inventor Andre C. DUMETZ

Andre C. DUMETZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20230046182
    Abstract: The present invention relates to a method of purifying a recombinant polypeptide from Host Cell Proteins (HCP), the method comprising: (a) applying a solution comprising the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer comprising caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support.
    Type: Application
    Filed: November 1, 2022
    Publication date: February 16, 2023
    Inventors: Andre C. DUMETZ, Kent E. GOKLEN, Nicholas E. LEVY, Jessica Rachel, Andrew S. THOMSON, Kenneth G. YANCEY
  • Methods for purifying antibodies
    Patent number: 11530238
    Abstract: The present invention relates to a method of purifying a recombinant polypeptide from Host Cell Proteins (HCP), the method comprising: (a) applying a solution comprising the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer comprising caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: December 20, 2022
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Andre C. Dumetz, Kent E. Goklen, Nicholas E. Levy, Jessica Rachel Molek, Andrew S. Thomson, Kenneth G. Yancey
  • METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20210284686
    Abstract: The present invention relates to a method of purifying a recombinant polypeptide from Host Cell Proteins (HCP), the method comprising: (a) applying a solution comprising the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer comprising caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support.
    Type: Application
    Filed: September 6, 2017
    Publication date: September 16, 2021
    Inventors: Andre C. DUMETZ, Kent E GOKLEN, Nicolas E LEVY, Jessica Rachel MOLEK, Andrew S. THOMSON, Kenneth G. YANCY
  • METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20210054023
    Abstract: A method of purifying a recombinant polypeptide from Host Cell Proteins (HCP) is provided. The method includes: (a) applying a solution containing the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer containing caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support, wherein the recombinant polypeptide is an anti-ICOS antibody or antigen binding fragment thereof.
    Type: Application
    Filed: March 6, 2019
    Publication date: February 25, 2021
    Inventors: Andre C. DUMETZ, Ken E. GOKLEN, Nicholas E. LEVY, Jessica R. MOLEK, Andrew S. THOMSON, Kenneth G. YANCEY