Patents by Inventor Andre Dodin

Andre Dodin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4898815
    Abstract: The invention provides a synthetic peptide which reproduces at least 5 of the 11 amino acids common to the .gamma. chain of sub-unit A of cholera toxin and the .gamma. chain of LT toxin of Escherichia coli. It is preferably constituted by a pentadecapeptide which corresponds to the following formula (I): ##STR1## The process of synthesis is by the step by step construction of the peptide chain starting from the C terminal end of said chain, by the successive fixing of the amino acids which constitute the latter. A novel medicament for the treatment of cholera and infectious gastro-enterites comprises said synthetic peptide as active constituent. A diagnosis agent for cholera and/or infectious gastro-enterites comprises a sequence of nucleotides corresponding to the 5 minimum amino acids of the synthetic peptide.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: February 6, 1990
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Odile Siffert, Georgette Le Thuillier, Patrice Allard
  • Patent number: 4751053
    Abstract: A magnetic device is provided for removing magnetic gel balls or the like from a liquid to be analyzed, biological or not, and transferring them to an immunoenzymatic quantitative analysis medium, which device is of the type comprising a ferromagnetic material rod, an oblong case made from a non-magnetic material partially enveloping the rod and a circuit for electromagnetically energizing the rod. The device further comprises structure for fixing and centering the rod by clamping.
    Type: Grant
    Filed: October 22, 1985
    Date of Patent: June 14, 1988
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Bernard Muller
  • Patent number: 4686281
    Abstract: The invention provides a synthetic peptide comprising at least 5 of the 11 amino acids common to the .gamma.chain of sub-unit A of the cholera toxin and the .gamma.chain of the LT toxin of Escherichia coli. The peptide is preferably constituted by a pentadecapeptide which corresponds to the following formula (I): ##STR1## The process of synthesis is by the step by step construction of the peptide chain starting form the C terminal end of said chain, by the successive fixing of the amino acids which constitute the peptide. A novel medicament for the treatment of cholera and infectious gastro-enterites is also disclosed which comprises said synthetic peptide as an active constituent. A diagnosis agent for cholera and/or infectious gastroenterites comprises a sequence of at least the 5 amino acids of the synthetic peptide.
    Type: Grant
    Filed: August 24, 1984
    Date of Patent: August 11, 1987
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Odile Siffert, Georgette Le Thuillier, Patrice Allard
  • Patent number: 4677055
    Abstract: A process for the immunobacteriological detection of pathogenic germs possessing specific antigenic determinants, and a kit for carrying out the process, with the aid of a magnetic gel to which are coupled anti-specific antigenic determinant antibodies, characterized by the following steps:(a) a biological medium supposedly contaminated by a pathogenic germ possessing a specific antigenic determinant is brought into contact with particles of the magnetic gel,(b) the particles of magnetic gel are then removed by magnetic means and(c) are inoculated onto a nutrient agar medium,(d) the agar medium is incubated to develop culture colonies of the pathogenic germs;(e) areas containing serum containing antibodies specific to the pathogenic germ to be detected are formed in the agar,(f) the germs are lysed by means of lysing agents,(g) the lysate is incubated with the serum for a time enabling the serological antibody-antigen reaction to take place by immunodiffusion on the agar, and(h) the quantity of germs containe
    Type: Grant
    Filed: December 7, 1983
    Date of Patent: June 30, 1987
    Assignee: Institut Pasteur
    Inventors: Andre Dodin, Eustrate Avrameas, Bruno Goud, Michel Guillou, Renee Nicolas