Patents by Inventor Andre DUMETZ

Andre DUMETZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PURIFYING RECOMBINANT POLYPEPTIDES
    Publication number: 20210054051
    Abstract: A method of purifying a recombinant polypeptide from a Host Cell Protein (HCP), wherein the amino acid sequence of the recombinant polypeptide comprises a cathepsin L cleavage site is provided. The method includes: (a) applying a solution containing the recombinant polypeptide and HCP to a superantigen chromatography solid support, (b) washing the superantigen chromatography solid support with a wash buffer containing caprylate and arginine; and (c) eluting the recombinant polypeptide from the superantigen chromatography solid support. A method of purifying an anti-OX40 antigen binding polypeptide from a Host Cell Protein (HCP) is also provided.
    Type: Application
    Filed: March 6, 2019
    Publication date: February 25, 2021
    Inventors: Andre DUMETZ, Kent E. GOKLEN, Nicholas E. LEVY, Jessica Rachel MOLEK, Andrew S. THOMSON, Kenneth G. YANCEY