Patents by Inventor Andre G. Routh
Andre G. Routh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7647102Abstract: A cardiac contractility modulating (CCM) device (30) includes an anti-arrhythmic therapy unit (38) for detecting a cardiac arrhythmia in a heart (2) of a patient based on processing electrical signals related to cardiac activity sensed at the heart, and for delivering anti-arrhythmic therapy to the heart. The device includes a cardiac contractility modulating (CCM) unit (40) capable of delivering cardiac contractility modulating (CCM) signals to the heart for modulating the contractility of a portion of the heart. The device may provide to the anti-arrhythmic therapy unit control signals associated with the delivery of the CCM signals to the heart. The control signals may be used to prevent interference of the CCM signals with the detecting of the cardiac arrhythmia. The device (30) includes a power source. The device may be an implantable device or a non-implantable device. The device may also include a pacing unit.Type: GrantFiled: November 18, 2005Date of Patent: January 12, 2010Assignee: Impulse Dynamics N.V.Inventors: Andre G. Routh, Edward Haluska, Nissim Darvish, David Prutchi, Ziv Belsky
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Patent number: 7027863Abstract: A multi-modal cardiotherapy device (100) includes an anti-arrhythmic unit (118) for delivering multiple types of anti-arrhythmic therapy to a heart, a cardiac contractility modulating unit (108) for delivering cardiac contractility modulating signals to the heart, and for applying anti-arrhythmic cardiac contractility modulating signal therapy to the heart, one or more sensing units (112) for sensing electrical signals related to electrical activity of the heart to provide an output signal, one or more detecting units (116) operatively connected to the sensing unit(s) (112) for detecting in the output signal cardiac events of the heart, a controller unit (106) operatively connected to the anti-arrhythmic unit (118), the cardiac contractility modulating unit (108) and the detecting unit(s) (116).Type: GrantFiled: October 25, 2000Date of Patent: April 11, 2006Assignee: Impulse Dynamics N.V.Inventors: David Prutchi, Nissim Darvish, Andre G. Routh, Edward Haluska, Ziv Belsky
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Patent number: 6993385Abstract: A cardiac contractility modulating (CCM) device includes an anti-arrhythmic therapy unit for detecting a cardiac arrhythmia in a heart of a patient based on processing electrical signals related to cardiac activity sensed at the heart, and for delivering anti-arrhythmic therapy to the heart. The device includes a cardiac contractility modulating unit capable of delivering cardiac contractility modulating signals to the heart for modulating the contractility of a portion of the heart. The device may provide to the anti-arrhythmic therapy unit control signals associated with the delivery of the CCM signals to the heart. The control signals may be used to prevent interference of the CCM signals with the detecting of the cardiac arrhythmia. The device includes a power source. The device may be an implantable device or a non-implantable device. The device may also include a pacing unit.Type: GrantFiled: October 24, 2000Date of Patent: January 31, 2006Assignee: Impulse Dynamics N.V.Inventors: Andre G. Routh, Edward Haluska, Nissim Darvish, David Prutchi, Ziv Belsky
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Patent number: 6694037Abstract: A spider-less and suspension-less speaker system, having a diaphragm constrained to move in a linear direction and supported by a frictionless or low friction support. A voice coil coupled to an audio input drives the speaker diaphragm. A position sensor determines the physical position of the diaphragm. A control circuit uses the sensed position information to modify the audio signal in such a way that the interaction of the voice coil and the magnetic field both drives the diaphragm to produce an audible output and restores the diaphragm to a neutral position in the absence of a further audio signal.Type: GrantFiled: December 10, 1999Date of Patent: February 17, 2004Inventors: Robert Steven Robinson, William B. Rottenberg, André G. Routh
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Patent number: 6597952Abstract: A method for setting the parameters of an alert time window in an excitable tissue control device operative under a plurality of different cardiac conditions of a heart of a patient. The method includes providing said excitable tissue control device with a set of data including a plurality of sets of alert time window parameters. Each set of window parameters is uniquely associated with a different set of values of a plurality of cardiac condition defining parameters identifying one of the different cardiac conditions. Each set of window parameters includes at least a set of timing parameters usable for obtaining a beginning time point and an ending time point of the alert window. The sets of window parameters are obtained by processing data collected within a data collection session from a plurality of cardiac beats of the same patient under the different cardiac conditions.Type: GrantFiled: February 12, 2001Date of Patent: July 22, 2003Assignee: Impulse Dynamics N. V.Inventors: Yuval Mika, David Prutchi, Ziv Belsky, Andre G. Routh
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Patent number: 6571122Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: GrantFiled: October 15, 2001Date of Patent: May 27, 2003Assignee: Intermedics Inc.Inventors: Edward A. Schroeppel, David Prutchi, André G. Routh
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Patent number: 6571121Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: GrantFiled: October 15, 2001Date of Patent: May 27, 2003Assignee: Intermedics Inc.Inventors: Edward A. Schroeppel, David Prutchi, André G. Routh
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Patent number: 6459928Abstract: Apparatus and method for obtaining from a patient's heart data useful for on-line setting of the parameters of a detection time window in an excitable tissue control device. The method includes applying electrodes to a first cardiac site and a second cardiac site of a patient and electrically connecting the electrodes to a data collecting device. The device is then operated under a plurality of different cardiac conditions to obtain a plurality of different histogram data sets. Each histogram data set represents a cumulative time distribution histogram of cardiac depolarization events detected at the second cardiac site in a plurality of cardiac beats. Each histogram data set is defined by a plurality of histogram parameters having values indicative of the cardiac conditions common to the plurality of cardiac beats used to obtain the histogram data set.Type: GrantFiled: January 24, 2001Date of Patent: October 1, 2002Assignee: Impulse Dynamics N.V.Inventors: Yuval Mika, David Prutchi, Ziv Belsky, Andre G. Routh
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Publication number: 20020072683Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: ApplicationFiled: October 15, 2001Publication date: June 13, 2002Inventors: Edward A. Schroeppel, David Prutchi, Andre G. Routh
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Publication number: 20020068875Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: ApplicationFiled: October 15, 2001Publication date: June 6, 2002Applicant: Intermedics, Inc.Inventors: Edward A. Schroeppel, David Prutchi, Andre G. Routh
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Publication number: 20010031925Abstract: Apparatus and method for obtaining from a patient's heart data useful for on-line setting of the parameters of a detection time window in an excitable tissue control device. The method includes applying electrodes to a first cardiac site and a second cardiac site of a patient and electrically connecting the electrodes to a data collecting device. The device is then operated under a plurality of different cardiac conditions to obtain a plurality of different histogram data sets. Each histogram data set represents a cumulative time distribution histogram of cardiac depolarization events detected at the second cardiac site in a plurality of cardiac beats. Each histogram data set is defined by a plurality of histogram parameters having values indicative of the cardiac conditions common to the plurality of cardiac beats used to obtain the histogram data set.Type: ApplicationFiled: January 24, 2001Publication date: October 18, 2001Inventors: Yuval Mika, David Prutchi, Ziv Belsky, Andre G. Routh
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Patent number: 6233487Abstract: A method for setting the parameters of an alert time window in an excitable tissue control device operative under a plurality of different cardiac conditions of a heart of a patient. The method includes providing said excitable tissue control device with a set of data including a plurality of sets of alert time window parameters. Each set of window parameters is uniquely associated with a different set of values of a plurality of cardiac condition defining parameters identifying one of the different cardiac conditions. Each set of window parameters includes at least a set of timing parameters usable for obtaining a beginning time point and an ending time point of the alert window. The sets of window parameters are obtained by processing data collected within a data collection session from a plurality of cardiac beats of the same patient under the different cardiac conditions.Type: GrantFiled: June 23, 1999Date of Patent: May 15, 2001Assignee: Impulse Dynamics N.V.Inventors: Yuval Mika, David Prutchi, Ziv Belsky, Andre G. Routh
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Patent number: 6223072Abstract: Apparatus and method for obtaining from a patient's heart data useful for on-line setting of the parameters of a detection time window in an excitable tissue control device. The method includes applying electrodes to a first cardiac site and a second cardiac site of a patient and electrically connecting the electrodes to a data collecting device. The device is then operated under a plurality of different cardiac conditions to obtain a plurality of different histogram data sets. Each histogram data set represents a cumulative time distribution histogram of cardiac depolarization events detected at the second cardiac site in a plurality of cardiac beats. Each histogram data set is defined by a plurality of histogram parameters having values indicative of the cardiac conditions common to the plurality of cardiac beats used to obtain the histogram data set.Type: GrantFiled: June 8, 1999Date of Patent: April 24, 2001Assignee: Impulse Dynamics N.V.Inventors: Yuval Mika, David Prutchi, Ziv Belsky, Andre G. Routh
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Patent number: 6144878Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: GrantFiled: January 5, 2000Date of Patent: November 7, 2000Assignee: Intermedics Inc.Inventors: Edward A. Schroeppel, David Prutchi, Andre G. Routh
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Patent number: 6096064Abstract: An endocardial apparatus for pacing four chambers of a heart, comprising: a power source housed in an implantable can, first, second and third leads having proximal and distal ends, each lead being electrically connected to the power source at its proximal end and extending into a vein proximal the heart, the first lead connecting at its distal end to an electrode that is in electrical contact with the right atrium of the heart, the second lead connecting at its distal end to an electrode that is in electrical contact with the right ventricle of the heart, the third lead connecting at a point proximal its distal end to a first electrode that is in electrical contact with the inside of the coronary sinus and oriented so as to stimulate the left atrium of the heart and connecting at its distal end to a second electrode that is in electrical contact with the inside of the great cardiac vein and oriented so as to stimulate the left ventricle of the heart.Type: GrantFiled: September 19, 1997Date of Patent: August 1, 2000Assignee: Intermedics Inc.Inventor: Andre G. Routh
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Patent number: 6035233Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: GrantFiled: January 9, 1998Date of Patent: March 7, 2000Assignee: Intermedics Inc.Inventors: Edward A. Schroeppel, David Prutchi, Andre G. Routh
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Patent number: 5749900Abstract: A method and apparatus for evaluating heart rate variability of the heart of a person in order to forecast a cardiac event. A cardiac stimulator receives heart beat signals from the heart and determines a measurement of heart rate variability based on statistical data derived from the heart beat signals and sensing data derived from a sensor. This measurement of heart rate variability is compared with previously stored heart rate variability zones defining normal and abnormal heart rate variability. These zones are modifiable after the occurrence of a cardiac event. Once a cardiac event is detected, a pathway is computed which extends from a generally normal heart rate variability condition to an abnormal heart rate variability condition. Subsequent measurements of heart rate variability are compared with this pathway. Selective therapy regimes are initiated depending on the measurement of heart rate variability.Type: GrantFiled: December 11, 1995Date of Patent: May 12, 1998Assignee: Sulzer Intermedics Inc.Inventors: Edward A. Schroeppel, David Prutchi, Andre G. Routh
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Patent number: 5086772Abstract: An arrhythmia control method and device are disclosed which monitor the cardiac state of a patient, utilize an arrhythmia recognition algorithm to detect and distinguish among bradycardia, sinus rhythm, supraventricular tachycardia and ventricular fibrillation, and deliver therapy in the form of electrical energy to cardiac tissue to revert selected arrhythmias and restore normal sinus rhythm. In its preferred form the device is an implantable combined dual chamber pacing and cardioverting device that is adapted to be electrically connected to the atrium and ventricle for sensing the atrial and ventricular waveforms and deliverying shock therapy thereto as required. The arrhythmia recognition algorithm utilizes the sensed atrial and ventricular waveform data for, among other things, distinguishing between ventricular tachycardia and supraventricular tachycardia.Type: GrantFiled: July 30, 1990Date of Patent: February 11, 1992Assignee: Telectronics Pacing Systems, Inc.Inventors: Donald J. Larnard, Andre G. Routh